5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part 1: Structure–activity relationship studies of 5-alkylamino pyrazoles and discovery of a potent, selective, and orally active analog
Sakya, Subas M., Lundy DeMello, Kristin M., Minich, Martha L., Rast, Bryson, Shavnya, Andrei, Rafka, Robert J., Koss, David A., Cheng, Hengmiao, Li, Jin, Jaynes, Burton H., Ziegler, Carl B., Mann, Donald W., Petras, Carol F., Seibel, Scott B., Silvia, Annette M., George, David M., Lund, Lisa A., Denis, Suzanne St, Hickman, Anne, Haven, Michelle L., Lynch, Michael P.
Published in Bioorganic & medicinal chemistry letters (15.01.2006)
Published in Bioorganic & medicinal chemistry letters (15.01.2006)
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Quantitative Structure−Activity Relationships among Macrolide Antibacterial Agents: In Vitro and in Vivo Potency against Pasteurella multocida
McFarland, James W, Berger, Cynthia M, Froshauer, Susan A, Hayashi, Shigeru F, Hecker, Scott J, Jaynes, Burton H, Jefson, Martin R, Kamicker, Barbara J, Lipinski, Christopher A, Lundy, Kristin M, Reese, Catherine P, Vu, Chi B
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Published in Journal of medicinal chemistry (25.04.1997)
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In Vitro Microbiological Characterization of a Novel Azalide, Two Triamilides and an Azalide Ketal against Bovine and Porcine Respiratory Pathogens
NORCIA, LAURA J. L., SILVIA, ANNETTE M., SANTORO, SHERYL L., RETSEMA, JIM, LETAVIC, MICHAEL A., BRONK, BRIAN S., LUNDY, KRISTIN M., YANG, BINGWEI, EVANS, NIGEL A., HAYASHI, SHIGERU F.
Published in Journal of antibiotics (2004)
Published in Journal of antibiotics (2004)
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Synthesis and SAR of heteroaryl-phenyl-substituted pyrazole derivatives as highly selective and potent canine COX-2 inhibitors
Cheng, Hengmiao, Lundy DeMello, Kristin M., Li, Jin, Sakya, Subas M., Ando, Kazuo, Kawamura, K., Kato, Tomoki, Rafka, Robert J., Jaynes, Burton H., Ziegler, Carl B., Stevens, Rod, Lund, Lisa A., Mann, Donald W., Kilroy, Carolyn, Haven, Michelle L., Nimz, Erik L., Dutra, Jason K., Li, Chao, Minich, Martha L., Kolosko, Nicole L., Petras, Carol, Silvia, Annette M., Seibel, Scott B.
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
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Azalide 3,6-Ketals: antibacterial activity and structure–Activity relationships of aryl and hetero aryl substituted analogues
Sakya, Subas M, Bertinato, Peter, Pratt, Bryan, Suarez-Contreras, Melani, Lundy, Kristin M, Minich, Martha L, Cheng, Hengmiao, Ziegler, Carl B, Kamicker, Barbara J, Hayashi, Shigeru F, Santoro, Sheryl L, George, David M, Bertsche, Camilla D
Published in Bioorganic & medicinal chemistry letters (07.04.2003)
Published in Bioorganic & medicinal chemistry letters (07.04.2003)
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Synthesis and SAR of azalide 3,6-ketal aromatic derivatives as potent gram-positive and gram-negative antibacterial agents
Cheng, Hengmiao, Dirlam, John P., Ziegler, Carl B., Lundy, Kristin M., Hayashi, Shigeru F., Kamicker, Barbara J., Dutra, Jason K., Daniel, Kirsten L., Santoro, Sheryl L., George, David M., Bertsche, Camilla D., Sakya, Subas M., Suarez-Contreras, Melani
Published in Bioorganic & medicinal chemistry letters (02.09.2002)
Published in Bioorganic & medicinal chemistry letters (02.09.2002)
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5-Heteroatom-substituted pyrazoles as canine COX-2 inhibitors: Part 2. Structure–activity relationship studies of 5-alkylethers and 5-thioethers
Sakya, Subas M., Cheng, Hengmiao, Lundy DeMello, Kristin M., Shavnya, Andrei, Minich, Martha L., Rast, Bryson, Dutra, Jason, Li, Chao, Rafka, Robert J., Koss, David A., Li, Jin, Jaynes, Burton H., Ziegler, Carl B., Mann, Donald W., Petras, Carol F., Seibel, Scott B., Silvia, Annette M., George, David M., Hickman, Anne, Haven, Michelle L., Lynch, Michael P.
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Repromicin Derivatives with Potent Antibacterial Activity against Pasteurella multocida
McFarland, James W, Hecker, Scott J, Jaynes, Burton H, Jefson, Martin R, Lundy, Kristin M, Vu, Chi B, Glazer, Edward A, Froshauer, Susan A, Hayashi, Shigeru F, Kamicker, Barbara J, Reese, Catherine P, Olson, Julie A
Published in Journal of medicinal chemistry (14.03.1997)
Published in Journal of medicinal chemistry (14.03.1997)
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Polar substituent effects in the bicyclo[2.2.2]octane ring system: polarography of 4-substituted bicyclo[2.2.2]oct-1-yl iodides
Adcock, William, Kok, Gaik B, Iyer, V. Sankar, Peters, Dennis G, Lundy, Kristin M, Kitching, William
Published in Journal of organic chemistry (01.02.1986)
Published in Journal of organic chemistry (01.02.1986)
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Discovery of a potent, selective and orally active canine COX-2 inhibitor, 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine
Li, Jin, DeMello, Kristin M.Lundy, Cheng, Henry, Sakya, Subas M., Bronk, Brian S., Rafka, Robert J., Jaynes, Burton H., Ziegler, Carl B., Kilroy, Carolyn, Mann, Donald W., Nimz, Eric L., Lynch, Michael P., Haven, Michelle L., Kolosko, Nicole L., Minich, Martha L., Li, Chao, Dutra, Jason K., Rast, Bryson, Crosson, Rhonda M., Morton, Barry J., Kirk, Glen W., Callaghan, Kathleen M., Koss, David A., Shavnya, Andrei, Lund, Lisa A., Seibel, Scott B., Petras, Carol F., Silvia, Annette
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
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