Oligonucleotide⁻Palladacycle Conjugates as Splice-Correcting Agents
Hande, Madhuri, Saher, Osama, Lundin, Karin E, Smith, C I Edvard, Zain, Rula, Lönnberg, Tuomas
Published in Molecules (Basel, Switzerland) (26.03.2019)
Published in Molecules (Basel, Switzerland) (26.03.2019)
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Journal Article
LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures
Pabon-Martinez, Y Vladimir, Xu, You, Villa, Alessandra, Lundin, Karin E, Geny, Sylvain, Nguyen, Chi-Hung, Pedersen, Erik B, Jørgensen, Per T, Wengel, Jesper, Nilsson, Lennart, Smith, C I Edvard, Zain, Rula
Published in Scientific reports (08.09.2017)
Published in Scientific reports (08.09.2017)
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Journal Article
The ability of locked nucleic acid oligonucleotides to pre-structure the double helix: A molecular simulation and binding study
Xu, You, Gissberg, Olof, Pabon-Martinez, Y Vladimir, Wengel, Jesper, Lundin, Karin E, Smith, C I Edvard, Zain, Rula, Nilsson, Lennart, Villa, Alessandra
Published in PloS one (12.02.2019)
Published in PloS one (12.02.2019)
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Journal Article
CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression
Zaghloul, Eman M, Gissberg, Olof, Moreno, Pedro M D, Siggens, Lee, Hällbrink, Mattias, Jørgensen, Anna S, Ekwall, Karl, Zain, Rula, Wengel, Jesper, Lundin, Karin E, Smith, C I Edvard
Published in Nucleic acids research (19.05.2017)
Published in Nucleic acids research (19.05.2017)
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Journal Article
Oligonucleotide Binding to Non-B-DNA in MYC
Umek, Tea, Sollander, Karin, Bergquist, Helen, Wengel, Jesper, Lundin, Karin E, Smith, C I Edvard, Zain, Rula
Published in Molecules (Basel, Switzerland) (12.03.2019)
Published in Molecules (Basel, Switzerland) (12.03.2019)
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Journal Article
Biological Activity and Biotechnological Aspects of Locked Nucleic Acids
Lundin, Karin E., Højland, Torben, Hansen, Bo R., Persson, Robert, Bramsen, Jesper B., Kjems, Jørgen, Koch, Troels, Wengel, Jesper, Smith, C.I. Edvard
Published in Advances in Genetics (2013)
Published in Advances in Genetics (2013)
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Book Chapter
Journal Article
Lipophilic Peptide Dendrimers for Delivery of Splice-Switching Oligonucleotides
Daralnakhla, Haneen, Saher, Osama, Zamolo, Susanna, Bazaz, Safa, P Bost, Jeremy, Heitz, Marc, Lundin, Karin E, El Andaloussi, Samir, Darbre, Tamis, Reymond, Jean-Louis, Zain, Rula, Smith, C I Edvard
Published in Pharmaceutics (01.01.2021)
Published in Pharmaceutics (01.01.2021)
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Journal Article
Eleven percent intact PGM3 in a severely immunodeficient patient with a novel splice-site mutation, a case report
Lundin, Karin E, Wang, Qing, Hamasy, Abdulrahman, Marits, Per, Uzunel, Mehmet, Wirta, Valtteri, Wikström, Ann-Charlotte, Fasth, Anders, Ekwall, Olov, Smith, C I Edvard
Published in BMC pediatrics (29.08.2018)
Published in BMC pediatrics (29.08.2018)
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Journal Article
RNA therapeutics inactivate PCSK9 by inducing a unique intracellular retention form
Rocha, Cristina S.J, Wiklander, Oscar P.B, Larsson, Lilian, Moreno, Pedro M.D, Parini, Paolo, Lundin, Karin E, Smith, C.I. Edvard
Published in Journal of molecular and cellular cardiology (01.05.2015)
Published in Journal of molecular and cellular cardiology (01.05.2015)
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Journal Article
Four Novel Splice-Switch Reporter Cell Lines: Distinct Impact of Oligonucleotide Chemistry and Delivery Vector on Biological Activity
Rocha, Cristina S.J., Lundin, Karin E., Behlke, Mark A., Zain, Rula, EL Andaloussi, Samir, Smith, C.I. Edvard
Published in Nucleic acid therapeutics (01.12.2016)
Published in Nucleic acid therapeutics (01.12.2016)
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Journal Article
Biological Activity and Biotechnological Aspects of Peptide Nucleic Acid
Lundin, Karin E., Good, Liam, Strömberg, Roger, Gräslund, Astrid, Smith, C. I. Edvard
Published in Advances in Genetics (2006)
Published in Advances in Genetics (2006)
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Book Chapter
Journal Article
Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression
Stenler, Sofia, Wiklander, Oscar PB, Badal-Tejedor, Maria, Turunen, Janne, Nordin, Joel Z, Hallengärd, David, Wahren, Britta, Andaloussi, Samir EL, Rutland, Mark W, Smith, CI Edvard, Lundin, Karin E, Blomberg, Pontus
Published in Molecular therapy. Nucleic acids (01.01.2014)
Published in Molecular therapy. Nucleic acids (01.01.2014)
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Journal Article
Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides: In Silico and in Vitro Studies
Hartono, Yossa Dwi, Pabon-Martinez, Y. Vladimir, Uyar, Arzu, Wengel, Jesper, Lundin, Karin E, Zain, Rula, Smith, C. I. Edvard, Nilsson, Lennart, Villa, Alessandra
Published in ACS omega (31.05.2017)
Published in ACS omega (31.05.2017)
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Journal Article
Zorro locked nucleic acid induces sequence-specific gene silencing
Ge, Rongbin, Heinonen, Juhana E, Svahn, Mathias G, Mohamed, Abdalla J, Lundin, Karin E, Smith, C.I. Edvard
Published in The FASEB journal (01.06.2007)
Published in The FASEB journal (01.06.2007)
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Journal Article
Repeatable, Inducible Micro-RNA-Based Technology Tightly Controls Liver Transgene Expression
Oprea, Iulian I, Viola, Joana R, Moreno, Pedro M D, Simonson, Oscar E, Rodin, Sergey, Teller, Nathalie, Tryggvason, Karl, Lundin, Karin E, Girnita, Leonard, Smith, Carl Inge Edvard
Published in Molecular therapy. Nucleic acids (01.07.2014)
Published in Molecular therapy. Nucleic acids (01.07.2014)
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Journal Article
Hypomorphic homozygous mutations in phosphoglucomutase 3 ( PGM3 ) impair immunity and increase serum IgE levels
Sassi, Atfa, PhD, Lazaroski, Sandra, PhD, Wu, Gang, MSc, Haslam, Stuart M., PhD, Fliegauf, Manfred, PhD, Mellouli, Fethi, MD, Patiroglu, Turkan, MD, Unal, Ekrem, MD, Ozdemir, Mehmet Akif, MD, Jouhadi, Zineb, MD, Khadir, Khadija, MD, Ben-Khemis, Leila, MSc, Ben-Ali, Meriem, PhD, Ben-Mustapha, Imen, MD, Borchani, Lamia, PhD, Pfeifer, Dietmar, PhD, Jakob, Thilo, MD, Khemiri, Monia, MD, Asplund, A. Charlotta, BSc, Gustafsson, Manuela O., MSc, Lundin, Karin E., PhD, Falk-Sörqvist, Elin, MSc, Moens, Lotte N., PhD, Gungor, Hatice Eke, MD, Engelhardt, Karin R., PhD, Dziadzio, Magdalena, MD, PhD, Stauss, Hans, MD, PhD, Fleckenstein, Bernhard, MD, Meier, Rebecca, BSc, Prayitno, Khairunnadiya, MSc, Maul-Pavicic, Andrea, PhD, Schaffer, Sandra, Rakhmanov, Mirzokhid, PhD, Henneke, Philipp, MD, Kraus, Helene, MSc, Eibel, Hermann, PhD, Kölsch, Uwe, MD, Nadifi, Sellama, PhD, Nilsson, Mats, PhD, Bejaoui, Mohamed, MD, Schäffer, Alejandro A., PhD, Smith, C.I. Edvard, MD, PhD, Dell, Anne, PhD, Barbouche, Mohamed-Ridha, MD, PhD, Grimbacher, Bodo, MD
Published in Journal of allergy and clinical immunology (01.05.2014)
Published in Journal of allergy and clinical immunology (01.05.2014)
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Journal Article
Chemical Development of Therapeutic Oligonucleotides
Lundin, Karin E, Gissberg, Olof, Smith, C I Edvard, Zain, Rula
Published in Methods in molecular biology (Clifton, N.J.) (2019)
Published in Methods in molecular biology (Clifton, N.J.) (2019)
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Journal Article
Novel peptide-dendrimer/lipid/oligonucleotide ternary complexes for efficient cellular uptake and improved splice-switching activity
Saher, Osama, Rocha, Cristina S.J., Zaghloul, Eman M., Wiklander, Oscar P.B., Zamolo, Susanna, Heitz, Marc, Ezzat, Kariem, Gupta, Dhanu, Reymond, Jean-Louis, Zain, Rula, Hollfelder, Florian, Darbre, Tamis, Lundin, Karin E., EL Andaloussi, Samir, Smith, C.I. Edvard
Published in European journal of pharmaceutics and biopharmaceutics (01.11.2018)
Published in European journal of pharmaceutics and biopharmaceutics (01.11.2018)
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Journal Article
2′-O-(N-(Aminoethyl)carbamoyl)methyl Modification Allows for Lower Phosphorothioate Content in Splice-Switching Oligonucleotides with Retained Activity
Honcharenko, Dmytro, Rocha, Cristina S J, Lundin, Karin E, Maity, Jyotirmoy, Milton, Stefan, Tedebark, Ulf, Murtola, Merita, Honcharenko, Malgorzata, Slaitas, Andis, Smith, C I Edvard, Zain, Rula, Strömberg, Roger
Published in Nucleic acid therapeutics (01.06.2022)
Published in Nucleic acid therapeutics (01.06.2022)
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