CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
Almqvist, Helena, Axelsson, Hanna, Jafari, Rozbeh, Dan, Chen, Mateus, André, Haraldsson, Martin, Larsson, Andreas, Molina, Daniel Martinez, Artursson, Per, Lundbäck, Thomas, Nordlund, Pär
Published in Nature communications (24.03.2016)
Published in Nature communications (24.03.2016)
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Journal Article
JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation
Lu, Ben, Antoine, Daniel J., Kwan, Kevin, Lundbäck, Peter, Wähämaa, Heidi, Schierbeck, Hanna, Robinson, Melissa, Van Zoelen, Marieke A. D., Yang, Huan, Li, Jianhua, Erlandsson-Harris, Helena, Chavan, Sangeeta S., Wang, Haichao, Andersson, Ulf, Tracey, Kevin J.
Published in Proceedings of the National Academy of Sciences - PNAS (25.02.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (25.02.2014)
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Journal Article
Novel role of PKR in inflammasome activation and HMGB1 release
Lu, Ben, Nakamura, Takahisa, Inouye, Karen, Li, Jianhua, Tang, Yiting, Lundbäck, Peter, Valdes-Ferrer, Sergio I., Olofsson, Peder S., Kalb, Thomas, Roth, Jesse, Zou, Yongrui, Erlandsson-Harris, Helena, Yang, Huan, Ting, Jenny P.-Y., Wang, Haichao, Andersson, Ulf, Antoine, Daniel J., Chavan, Sangeeta S., Hotamisligil, Gökhan S., Tracey, Kevin J.
Published in Nature (London) (30.08.2012)
Published in Nature (London) (30.08.2012)
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Journal Article
Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis
Agalave, Nilesh M., Larsson, Max, Abdelmoaty, Sally, Su, Jie, Baharpoor, Azar, Lundbäck, Peter, Palmblad, Karin, Andersson, Ulf, Harris, Helena, Svensson, Camilla I.
Published in Pain (Amsterdam) (01.09.2014)
Published in Pain (Amsterdam) (01.09.2014)
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Journal Article
MD-2 is required for disulfide HMGB1-dependent TLR4 signaling
Yang, Huan, Wang, Haichao, Ju, Zhongliang, Ragab, Ahmed A, Lundbäck, Peter, Long, Wei, Valdes-Ferrer, Sergio I, He, Mingzhu, Pribis, John P, Li, Jianhua, Lu, Ben, Gero, Domokos, Szabo, Csaba, Antoine, Daniel J, Harris, Helena E, Golenbock, Doug T, Meng, Jianmin, Roth, Jesse, Chavan, Sangeeta S, Andersson, Ulf, Billiar, Timothy R, Tracey, Kevin J, Al-Abed, Yousef
Published in The Journal of experimental medicine (12.01.2015)
Published in The Journal of experimental medicine (12.01.2015)
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Journal Article
CETSA beyond Soluble Targets: a Broad Application to Multipass Transmembrane Proteins
Kawatkar, Aarti, Schefter, Michelle, Hermansson, Nils-Olov, Snijder, Arjan, Dekker, Niek, Brown, Dean G, Lundbäck, Thomas, Zhang, Andrew X, Castaldi, M. Paola
Published in ACS chemical biology (20.09.2019)
Published in ACS chemical biology (20.09.2019)
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Journal Article
Redox modifications of cysteine residues regulate the cytokine activity of HMGB1
Yang, Huan, Lundbäck, Peter, Ottosson, Lars, Erlandsson-Harris, Helena, Venereau, Emilie, Bianchi, Marco E, Al-Abed, Yousef, Andersson, Ulf, Tracey, Kevin J
Published in Molecular medicine (Cambridge, Mass.) (07.06.2021)
Published in Molecular medicine (Cambridge, Mass.) (07.06.2021)
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Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery
Mateus, André, Gordon, Laurie J., Wayne, Gareth J., Almqvist, Helena, Axelsson, Hanna, Seashore-Ludlow, Brinton, Treyer, Andrea, Matsson, Pär, Lundbäck, Thomas, West, Andy, Hann, Michael M., Artursson, Per
Published in Proceedings of the National Academy of Sciences - PNAS (25.07.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (25.07.2017)
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Journal Article
Shared genetic loci for body fat storage and adipocyte lipolysis in humans
Kulyté, Agné, Lundbäck, Veroniqa, Arner, Peter, Strawbridge, Rona J., Dahlman, Ingrid
Published in Scientific reports (07.03.2022)
Published in Scientific reports (07.03.2022)
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Journal Article
Sex- and cell-dependent contribution of peripheral high mobility group box 1 and TLR4 in arthritis-induced pain
Rudjito, Resti, Agalave, Nilesh M, Farinotti, Alex Bersellini, Lundbäck, Peter, Szabo-Pardi, Thomas A, Price, Theodore J, Harris, Helena Erlandsson, Burton, Michael D, Svensson, Camilla I
Published in Pain (Amsterdam) (01.02.2021)
Published in Pain (Amsterdam) (01.02.2021)
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Journal Article
Increase in pollen sensitization in Swedish adults and protective effect of keeping animals in childhood
Bjerg, A., Ekerljung, L., Eriksson, J., Näslund, J., Sjölander, S., Rönmark, E., Dahl, Å., Holmberg, K., Wennergren, G., Torén, K., Borres, M. P., Lötvall, J., Lundbäck, B.
Published in Clinical and experimental allergy (01.10.2016)
Published in Clinical and experimental allergy (01.10.2016)
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Inhibition of Insulin-Regulated Aminopeptidase by Imidazo [1,5-α]pyridines-Synthesis and Evaluation
Engen, Karin, Lundbäck, Thomas, Yadav, Anubha, Puthiyaparambath, Sharathna, Rosenström, Ulrika, Gising, Johan, Jenmalm-Jensen, Annika, Hallberg, Mathias, Larhed, Mats
Published in International journal of molecular sciences (21.02.2024)
Published in International journal of molecular sciences (21.02.2024)
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Journal Article
Chronic snus use in healthy males alters endothelial function and increases arterial stiffness
Antoniewicz, Lukasz, Kabele, Mikael, Nilsson, Ulf, Pourazar, Jamshid, Rankin, Gregory, Bosson, Jenny A, Lundbäck, Magnus
Published in PloS one (03.06.2022)
Published in PloS one (03.06.2022)
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A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug‐induced liver injury and postinjury inflammation in mice
Lundbäck, Peter, Lea, Jonathan D., Sowinska, Agnieszka, Ottosson, Lars, Fürst, Camilla Melin, Steen, Johanna, Aulin, Cecilia, Clarke, Joanna I., Kipar, Anja, Klevenvall, Lena, Yang, Huan, Palmblad, Karin, Park, B. Kevin, Tracey, Kevin J., Blom, Anna M., Andersson, Ulf, Antoine, Daniel J., Erlandsson Harris, Helena
Published in Hepatology (Baltimore, Md.) (01.11.2016)
Published in Hepatology (Baltimore, Md.) (01.11.2016)
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Journal Article
Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis
Brunner, Katharina, Maric, Selma, Reshma, Rudraraju Srilakshmi, Almqvist, Helena, Seashore-Ludlow, Brinton, Gustavsson, Anna-Lena, Poyraz, Ömer, Yogeeswari, Perumal, Lundbäck, Thomas, Vallin, Michaela, Sriram, Dharmarajan, Schnell, Robert, Schneider, Gunter
Published in Journal of medicinal chemistry (28.07.2016)
Published in Journal of medicinal chemistry (28.07.2016)
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