Pyruvate formate-lyase activating enzyme: The catalytically active 5'-deoxyadenosyl radical caught in the act of H-atom abstraction
Lundahl, Maike N, Yang, Hao, Broderick, William E, Hoffman, Brian M, Broderick, Joan B
Published in Proceedings of the National Academy of Sciences - PNAS (21.11.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (21.11.2023)
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ENDOR Spectroscopy Reveals the “Free” 5′-Deoxyadenosyl Radical in a Radical SAM Enzyme Active Site Actually is Chaperoned by Close Interaction with the Methionine-Bound [4Fe–4S]2+ Cluster
Yang, Hao, Ho, Madeline B., Lundahl, Maike N., Mosquera, Martín A., Broderick, William E., Broderick, Joan B., Hoffman, Brian M.
Published in Journal of the American Chemical Society (14.02.2024)
Published in Journal of the American Chemical Society (14.02.2024)
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Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage
Moody, James D., Hill, Sarah, Lundahl, Maike N., Saxton, Aubrianna J., Galambas, Amanda, Broderick, William E., Lawrence, C. Martin, Broderick, Joan B.
Published in The Journal of biological chemistry (01.06.2023)
Published in The Journal of biological chemistry (01.06.2023)
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Exploring the influence of H-bonding and ligand constraints on thiolate ligated non-heme iron mediated dioxygen activation
Lundahl, Maike N., Greiner, Maria B., Piquette, Marc C., Gannon, Paige M., Kaminsky, Werner, Kovacs, Julie A.
Published in Chemical science (Cambridge) (14.08.2024)
Published in Chemical science (Cambridge) (14.08.2024)
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Mechanism of Radical S‑Adenosyl- l-methionine Adenosylation: Radical Intermediates and the Catalytic Competence of the 5′-Deoxyadenosyl Radical
Lundahl, Maike N, Sarksian, Raymond, Yang, Hao, Jodts, Richard J, Pagnier, Adrien, Smith, Donald F, Mosquera, Martín A, van der Donk, Wilfred A, Hoffman, Brian M, Broderick, William E, Broderick, Joan B
Published in Journal of the American Chemical Society (23.03.2022)
Published in Journal of the American Chemical Society (23.03.2022)
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Journal Article
ENDOR Spectroscopy Reveals the "Free" 5'-Deoxyadenosyl Radical in a Radical SAM Enzyme Active Site Actually is Chaperoned by Close Interaction with the Methionine-Bound 4Fe-4S2+ Cluster
Yang, Hao, Ho, Madeline B, Lundahl, Maike N, Mosquera, Martín A, Broderick, William E, Broderick, Joan B, Hoffman, Brian M
Published in Journal of the American Chemical Society (14.02.2024)
Published in Journal of the American Chemical Society (14.02.2024)
Get full text
Journal Article