Notch signaling in T cells is essential for allergic airway inflammation, but expression of the Notch ligands Jagged 1 and Jagged 2 on dendritic cells is dispensable
Tindemans, Irma, MSc, Lukkes, Melanie, BSc, de Bruijn, Marjolein J.W., BSc, Li, Bobby W.S., MSc, van Nimwegen, Menno, BSc, Amsen, Derk, PhD, KleinJan, Alex, PhD, Hendriks, Rudi W., PhD
Published in Journal of allergy and clinical immunology (01.10.2017)
Published in Journal of allergy and clinical immunology (01.10.2017)
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Journal Article
Group 2 Innate Lymphoid Cells Exhibit a Dynamic Phenotype in Allergic Airway Inflammation
Li, Bobby W S, Stadhouders, Ralph, de Bruijn, Marjolein J W, Lukkes, Melanie, Beerens, Dior M J M, Brem, Maarten D, KleinJan, Alex, Bergen, Ingrid, Vroman, Heleen, Kool, Mirjam, van IJcken, Wilfred F J, Rao, Tata Nageswara, Fehling, Hans Jörg, Hendriks, Rudi W
Published in Frontiers in immunology (01.12.2017)
Published in Frontiers in immunology (01.12.2017)
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Dendritic cell vaccination and CD40-agonist combination therapy licenses T cell-dependent antitumor immunity in a pancreatic carcinoma murine model
Lau, Sai Ping, van Montfoort, Nadine, Kinderman, Priscilla, Lukkes, Melanie, Klaase, Larissa, van Nimwegen, Menno, van Gulijk, Mandy, Dumas, Jasper, Mustafa, Dana A M, Lievense, Sanne L A, Groeneveldt, Christianne, Stadhouders, Ralph, Li, Yunlei, Stubbs, Andrew, Marijt, Koen A, Vroman, Heleen, van der Burg, Sjoerd H, Aerts, Joachim, van Hall, Thorbald, Dammeijer, Floris, van Eijck, Casper H J
Published in Journal for immunotherapy of cancer (01.07.2020)
Published in Journal for immunotherapy of cancer (01.07.2020)
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Journal Article
Immune monitoring in mesothelioma patients identifies novel immune-modulatory functions of gemcitabine associating with clinical response
Dammeijer, Floris, De Gooijer, Cornedine J., van Gulijk, Mandy, Lukkes, Melanie, Klaase, Larissa, Lievense, Lysanne A., Waasdorp, Cynthia, Jebbink, Merel, Bootsma, Gerben P., Stigt, Jos A., Biesma, Bonne, Kaijen-Lambers, Margaretha E.H., Mankor, Joanne, Vroman, Heleen, Cornelissen, Robin, Baas, Paul, Van der Noort, Vincent, Burgers, Jacobus A., Aerts, Joachim G.
Published in EBioMedicine (01.02.2021)
Published in EBioMedicine (01.02.2021)
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Immune Responses after Heavy Alcohol Consumption: Cytokine Concentrations in Hangover-Sensitive and Hangover-Resistant Drinkers
van de Loo, Aurora Jae, Raasveld, S Jorinde, Hogewoning, Anna, Zeeuw, Raymond de, Bosma, Else R, Bouwmeester, Noor H, Lukkes, Melanie, Knipping, Karen, Mackus, Marlou, Kraneveld, Aletta D, Brookhuis, Karel A, Garssen, Johan, Scholey, Andrew, Verster, Joris C
Published in Healthcare (Basel) (01.04.2021)
Published in Healthcare (Basel) (01.04.2021)
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Journal Article
The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes
Dammeijer, Floris, van Gulijk, Mandy, Mulder, Evalyn E., Lukkes, Melanie, Klaase, Larissa, van den Bosch, Thierry, van Nimwegen, Menno, Lau, Sai Ping, Latupeirissa, Kitty, Schetters, Sjoerd, van Kooyk, Yvette, Boon, Louis, Moyaart, Antien, Mueller, Yvonne M., Katsikis, Peter D., Eggermont, Alexander M., Vroman, Heleen, Stadhouders, Ralph, Hendriks, Rudi W., Thüsen, Jan von der, Grünhagen, Dirk J., Verhoef, Cornelis, van Hall, Thorbald, Aerts, Joachim G.
Published in Cancer cell (09.11.2020)
Published in Cancer cell (09.11.2020)
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Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease
Corneth, Odilia B. J., Verstappen, Gwenny M. P., Paulissen, Sandra M. J., de Bruijn, Marjolein J. W., Rip, Jasper, Lukkes, Melanie, van Hamburg, Jan Piet, Lubberts, Erik, Bootsma, Hendrika, Kroese, Frans G. M., Hendriks, Rudi W.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2017)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2017)
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Journal Article
T cells and ILC2s are major effector cells in influenza‐induced exacerbation of allergic airway inflammation in mice
Li, Bobby W. S., de Bruijn, Marjolein J. W., Lukkes, Melanie, Nimwegen, Menno, Bergen, Ingrid M., KleinJan, Alex, GeurtsvanKessel, Corine H., Andeweg, Arno, Rimmelzwaan, Guus F., Hendriks, Rudi W.
Published in European journal of immunology (01.01.2019)
Published in European journal of immunology (01.01.2019)
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Journal Article
T cells are necessary for ILC2 activation in house dust mite‐induced allergic airway inflammation in mice
Li, Bobby W. S., Bruijn, Marjolein J. W., Tindemans, Irma, Lukkes, Melanie, KleinJan, Alex, Hoogsteden, Henk C., Hendriks, Rudi W.
Published in European journal of immunology (01.06.2016)
Published in European journal of immunology (01.06.2016)
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Journal Article
Type II conventional dendritic cells of asthmatic patients with frequent exacerbations have an altered phenotype and frequency
Vroman, Heleen, Tindemans, Irma, Lukkes, Melanie, van Nimwegen, Menno, de Boer, Geertje M., Tramper-Stranders, Gerdien A., Braunstahl, Gert-Jan, Hendriks, Rudi W., Kool, Mirjam
Published in The European respiratory journal (01.06.2020)
Published in The European respiratory journal (01.06.2020)
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Journal Article
Notch signaling licenses allergic airway inflammation by promoting Th2 cell lymph node egress
Tindemans, Irma, van Schoonhoven, Anne, KleinJan, Alex, de Bruijn, Marjolein Jw, Lukkes, Melanie, van Nimwegen, Menno, van den Branden, Anouk, Bergen, Ingrid M, Corneth, Odilia Bj, van IJcken, Wilfred Fj, Stadhouders, Ralph, Hendriks, Rudi W
Published in The Journal of clinical investigation (01.07.2020)
Published in The Journal of clinical investigation (01.07.2020)
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Journal Article
Increased surface expression of NOTCH on memory T cells in peripheral blood from patients with asthma
Tindemans, Irma, Vroman, Heleen, Lukkes, Melanie, van Nimwegen, Menno, de Bruijn, Marjolein J.W., Li, Bobby W.S., Kleinjan, Alex, de Boer, Geertje M., Tramper-Stranders, Gerdien A., Kool, Mirjam, Braunstahl, Gert-Jan, Hendriks, Rudi W.
Published in Journal of allergy and clinical immunology (01.02.2019)
Published in Journal of allergy and clinical immunology (01.02.2019)
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Journal Article
The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma
KleinJan, Alex, Tindemans, Irma, Montgomery, Jeffrey E., Lukkes, Melanie, de Bruijn, Marjolein J.W., van Nimwegen, Menno, Bergen, Ingrid, Moellering, Raymond E., Hoogsteden, Henk C., Boon, Louis, Amsen, Derk, Hendriks, R.W.
Published in Journal of allergy and clinical immunology (01.07.2018)
Published in Journal of allergy and clinical immunology (01.07.2018)
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Journal Article
Type II conventional DCs of asthmatic patients with frequent exacerbations have an altered phenotype and frequency
Vroman, Heleen, Tindemans, Irma, Lukkes, Melanie, van Nimwegen, Menno, de Boer, Geertje M, Tramper-Stranders, Gerdien A, Braunstahl, Gert-Jan, Hendriks, Rudi W, Kool, Mirjam
Published in The European respiratory journal (01.05.2020)
Published in The European respiratory journal (01.05.2020)
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Journal Article
Tnfaip3 expression in pulmonary conventional type 1 Langerin‐expressing dendritic cells regulates T helper 2‐mediated airway inflammation in mice
Vroman, Heleen, Uden, Denise, Bergen, Ingrid M., Hulst, Jennifer A. C., Lukkes, Melanie, Loo, Geert, Clausen, Björn E., Boon, Louis, Lambrecht, Bart N., Hammad, Hamida, Hendriks, Rudi W., Kool, Mirjam
Published in Allergy (Copenhagen) (01.10.2020)
Published in Allergy (Copenhagen) (01.10.2020)
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Journal Article
Effect of targeting CD40 for DC vaccination in pancreatic adenocarcinoma
Lau, Sai Ping, van Montfoort, Nadine, Kinderman, Priscilla, Lukkes, Melanie, Dumas, Jasper, van Nimwegen, Menno, Mustafa, Dana, Vroman, Heleen, van Hall, Thorbald, van der Burg, Sjoerd H., Aerts, Joachim G.J.V., Dammeijer, Floris, van Eijck, Casper H.J.
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Journal Article
02.45Enhanced bruton's tyrosine kinase activity in peripheral blood b lymphocytes of autoimmune disease patients
Corneth, Odilia BJ, Verstappen, Gwenny MP, Paulissen, Sandra MJ, de Bruijn, Marjolein JW, Rip, Jasper, Lukkes, Melanie, van Hamburg, Jan Piet, Lubberts, Erik, Bootsma, Hendrika, Kroese, Frans GM, Hendriks, Rudi W
Published in Annals of the rheumatic diseases (01.03.2017)
Published in Annals of the rheumatic diseases (01.03.2017)
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Journal Article
A pathophysiological role of PDE3 in allergic airway inflammation
Beute, Jan, Lukkes, Melanie, Koekoek, Ewout P, Nastiti, Hedwika, Ganesh, Keerthana, de Bruijn, Marjolein Jw, Hockman, Steve, van Nimwegen, Menno, Braunstahl, Gert-Jan, Boon, Louis, Lambrecht, Bart N, Manganiello, Vince C, Hendriks, Rudi W, KleinJan, Alex
Published in JCI insight (25.01.2018)
Published in JCI insight (25.01.2018)
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Journal Article
02.45 Enhanced bruton’s tyrosine kinase activity in peripheral blood b lymphocytes of autoimmune disease patients
Corneth, Odilia B.J., Verstappen, Gwenny M.P., Paulissen, Sandra M.J., de Bruijn, Marjolein J.W., Rip, Jasper, Lukkes, Melanie, van Hamburg, Jan Piet, Lubberts, Erik, Bootsma, Hendrika, Kroese, Frans G.M., Hendriks, Rudi W.
Published in Annals of the rheumatic diseases (01.03.2017)
Published in Annals of the rheumatic diseases (01.03.2017)
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