Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control
Amiram, Miriam, Luginbuhl, Kelli M., Li, Xinghai, Feinglos, Mark N., Chilkoti, Ashutosh
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (19.02.2013)
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One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer
Luginbuhl, Kelli M., Schaal, Jeffrey L., Umstead, Bret, Mastria, Eric M., Li, Xinghai, Banskota, Samagya, Arnold, Susan, Feinglos, Mark, D’Alessio, David, Chilkoti, Ashutosh
Published in Nature biomedical engineering (05.06.2017)
Published in Nature biomedical engineering (05.06.2017)
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Controlled release of biologics for the treatment of type 2 diabetes
Gilroy, Caslin A., Luginbuhl, Kelli M., Chilkoti, Ashutosh
Published in Journal of controlled release (28.10.2016)
Published in Journal of controlled release (28.10.2016)
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Genetically encoded lipid–polypeptide hybrid biomaterials that exhibit temperature-triggered hierarchical self-assembly
Mozhdehi, Davoud, Luginbuhl, Kelli M., Simon, Joseph R., Dzuricky, Michael, Berger, Rüdiger, Varol, H. Samet, Huang, Fred C., Buehne, Kristen L., Mayne, Nicholas R., Weitzhandler, Isaac, Bonn, Mischa, Parekh, Sapun H., Chilkoti, Ashutosh
Published in Nature chemistry (01.05.2018)
Published in Nature chemistry (01.05.2018)
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Recombinant Synthesis of Hybrid Lipid–Peptide Polymer Fusions that Self‐Assemble and Encapsulate Hydrophobic Drugs
Luginbuhl, Kelli M., Mozhdehi, Davoud, Dzuricky, Michael, Yousefpour, Parisa, Huang, Fred C., Mayne, Nicholas R., Buehne, Kristen L., Chilkoti, Ashutosh
Published in Angewandte Chemie International Edition (06.11.2017)
Published in Angewandte Chemie International Edition (06.11.2017)
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Journal Article
Genetically Encoded Cholesterol-Modified Polypeptides
Mozhdehi, Davoud, Luginbuhl, Kelli M, Dzuricky, Michael, Costa, Simone A, Xiong, Sinan, Huang, Fred C, Lewis, Mae M, Zelenetz, Stephanie R, Colby, Christian D, Chilkoti, Ashutosh
Published in Journal of the American Chemical Society (16.01.2019)
Published in Journal of the American Chemical Society (16.01.2019)
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Ultrasensitive point-of-care immunoassay for secreted glycoprotein detects Ebola infection earlier than PCR
Fontes, Cassio M, Lipes, Barbara D, Liu, Jason, Agans, Krystle N, Yan, Aiwei, Shi, Patricia, Cruz, Daniela F, Kelly, Garrett, Luginbuhl, Kelli M, Joh, Daniel Y, Foster, Stephanie L, Heggestad, Jacob, Hucknall, Angus, Mikkelsen, Maiken H, Pieper, Carl F, Horstmeyer, Roarke W, Geisbert, Thomas W, Gunn, Michael D, Chilkoti, Ashutosh
Published in Science translational medicine (07.04.2021)
Published in Science translational medicine (07.04.2021)
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A brush-polymer/exendin-4 conjugate reduces blood glucose levels for up to five days and eliminates poly(ethylene glycol) antigenicity
Qi, Yizhi, Simakova, Antonina, Ganson, Nancy J., Li, Xinghai, Luginbuhl, Kelli M., Ozer, Imran, Liu, Wenge, Hershfield, Michael S., Matyjaszewski, Krzysztof, Chilkoti, Ashutosh
Published in Nature biomedical engineering (01.01.2017)
Published in Nature biomedical engineering (01.01.2017)
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Journal Article
Recombinant Synthesis of Hybrid Lipid–Peptide Polymer Fusions that Self‐Assemble and Encapsulate Hydrophobic Drugs
Luginbuhl, Kelli M., Mozhdehi, Davoud, Dzuricky, Michael, Yousefpour, Parisa, Huang, Fred C., Mayne, Nicholas R., Buehne, Kristen L., Chilkoti, Ashutosh
Published in Angewandte Chemie (06.11.2017)
Published in Angewandte Chemie (06.11.2017)
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Journal Article
A brush-polymer conjugate of exendin-4 reduces blood glucose for up to five days and eliminates poly(ethylene glycol) antigenicity
Qi, Yizhi, Simakova, Antonina, Ganson, Nancy J, Li, Xinghai, Luginbuhl, Kelli M, Özer, Imran, Liu, Wenge, Hershfield, Michael S, Matyjaszewski, Krzysztof, Chilkoti, Ashutosh
Published in Nature biomedical engineering (2016)
Published in Nature biomedical engineering (2016)
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