Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms
Spangler, Jamie B., Tomala, Jakub, Luca, Vincent C., Jude, Kevin M., Dong, Shen, Ring, Aaron M., Votavova, Petra, Pepper, Marion, Kovar, Marek, Garcia, K. Christopher
Published in Immunity (Cambridge, Mass.) (19.05.2015)
Published in Immunity (Cambridge, Mass.) (19.05.2015)
Get full text
Journal Article
Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity
Luca, Vincent C., Kim, Byoung Choul, Ge, Chenghao, Kakuda, Shinako, Wu, Di, Roein-Peikar, Mehdi, Haltiwanger, Robert S., Zhu, Cheng, Ha, Taekjip, Garcia, K. Christopher
Published in Science (American Association for the Advancement of Science) (24.03.2017)
Published in Science (American Association for the Advancement of Science) (24.03.2017)
Get full text
Journal Article
The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
de Mingo Pulido, Álvaro, Hänggi, Kay, Celias, Daiana P., Gardner, Alycia, Li, Jie, Batista-Bittencourt, Bruna, Mohamed, Eslam, Trillo-Tinoco, Jimena, Osunmakinde, Olabisi, Peña, Reymi, Onimus, Alexis, Kaisho, Tsuneyasu, Kaufmann, Johanna, McEachern, Kristen, Soliman, Hatem, Luca, Vincent C., Rodriguez, Paulo C., Yu, Xiaoqing, Ruffell, Brian
Published in Immunity (Cambridge, Mass.) (08.06.2021)
Published in Immunity (Cambridge, Mass.) (08.06.2021)
Get full text
Journal Article
Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal
Yan, Kelley S., Janda, Claudia Y., Chang, Junlei, Zheng, Grace X. Y., Larkin, Kathryn A., Luca, Vincent C., Chia, Luis A., Mah, Amanda T., Han, Arnold, Terry, Jessica M., Ootani, Akifumi, Roelf, Kelly, Lee, Mark, Yuan, Jenny, Li, Xiao, Bolen, Christopher R., Wilhelmy, Julie, Davies, Paige S., Ueno, Hiroo, von Furstenberg, Richard J., Belgrader, Phillip, Ziraldo, Solongo B., Ordonez, Heather, Henning, Susan J., Wong, Melissa H., Snyder, Michael P., Weissman, Irving L., Hsueh, Aaron J., Mikkelsen, Tarjei S., Garcia, K. Christopher, Kuo, Calvin J.
Published in Nature (London) (11.05.2017)
Published in Nature (London) (11.05.2017)
Get full text
Journal Article
Structural basis of GPBAR activation and bile acid recognition
Yang, Fan, Mao, Chunyou, Guo, Lulu, Lin, Jingyu, Ming, Qianqian, Xiao, Peng, Wu, Xiang, Shen, Qingya, Guo, Shimeng, Shen, Dan-Dan, Lu, Ruirui, Zhang, Linqi, Huang, Shenming, Ping, Yuqi, Zhang, Chenlu, Ma, Cheng, Zhang, Kai, Liang, Xiaoying, Shen, Yuemao, Nan, Fajun, Yi, Fan, Luca, Vincent C., Zhou, Jiuyao, Jiang, Changtao, Sun, Jin-Peng, Xie, Xin, Yu, Xiao, Zhang, Yan
Published in Nature (London) (19.11.2020)
Published in Nature (London) (19.11.2020)
Get full text
Journal Article
Crystal Structure of the Japanese Encephalitis Virus Envelope Protein
LUCA, Vincent C, ABIMANSOUR, Jad, NELSON, Christopher A, FREMONT, Daved H
Published in Journal of Virology (01.02.2012)
Published in Journal of Virology (01.02.2012)
Get full text
Journal Article
Structure of the planar cell polarity cadherins Fat4 and Dachsous1
Medina, Elliot, Easa, Yathreb, Lester, Daniel K., Lau, Eric K., Sprinzak, David, Luca, Vincent C.
Published in Nature communications (16.02.2023)
Published in Nature communications (16.02.2023)
Get full text
Journal Article
Notch1 Phase Separation Coupled Percolation facilitates target gene expression and enhancer looping
Foran, Gregory, Hallam, Ryan Douglas, Megaly, Marvel, Turgambayeva, Anel, Antfolk, Daniel, Li, Yifeng, Luca, Vincent C., Necakov, Aleksandar
Published in Scientific reports (19.09.2024)
Published in Scientific reports (19.09.2024)
Get full text
Journal Article
Inhibition of Delta-induced Notch signaling using fucose analogs
Schneider, Michael, Kumar, Vivek, Nordstrøm, Lars Ulrik, Feng, Lei, Takeuchi, Hideyuki, Hao, Huilin, Luca, Vincent C, Garcia, K Christopher, Stanley, Pamela, Wu, Peng, Haltiwanger, Robert S
Published in Nature chemical biology (01.01.2018)
Published in Nature chemical biology (01.01.2018)
Get full text
Journal Article
Structural basis for mouse LAG3 interactions with the MHC class II molecule I-Ab
Ming, Qianqian, Antfolk, Daniel, Price, David A., Manturova, Anna, Medina, Elliot, Singh, Srishti, Mason, Charlotte, Tran, Timothy H., Smalley, Keiran S. M., Leung, Daisy W., Luca, Vincent C.
Published in Nature communications (29.08.2024)
Published in Nature communications (29.08.2024)
Get full text
Journal Article
Affinity-matured DLL4 ligands as broad-spectrum modulators of Notch signaling
Gonzalez-Perez, David, Das, Satyajit, Antfolk, Daniel, Ahsan, Hadia S., Medina, Elliot, Dundes, Carolyn E., Jokhai, Rayyan T., Egan, Emily D., Blacklow, Stephen C., Loh, Kyle M., Rodriguez, Paulo C., Luca, Vincent C.
Published in Nature chemical biology (01.01.2023)
Published in Nature chemical biology (01.01.2023)
Get full text
Journal Article
Soluble and multivalent Jag1 DNA origami nanopatterns activate Notch without pulling force
Smyrlaki, Ioanna, Fördős, Ferenc, Rocamonde-Lago, Iris, Wang, Yang, Shen, Boxuan, Lentini, Antonio, Luca, Vincent C., Reinius, Björn, Teixeira, Ana I., Högberg, Björn
Published in Nature communications (18.01.2024)
Published in Nature communications (18.01.2024)
Get full text
Journal Article
Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling
Luca, Vincent C, Miao, Yi, Li, Xingnan, Hollander, Michael J, Kuo, Calvin J, Garcia, K Christopher
Published in PloS one (08.01.2020)
Published in PloS one (08.01.2020)
Get full text
Journal Article
Neutralizing Monoclonal Antibodies against Hepatitis C Virus E2 Protein Bind Discontinuous Epitopes and Inhibit Infection at a Postattachment Step
SABO, Michelle C, LUCA, Vincent C, FREMONT, Daved H, DIAMOND, Michael S, PRENTOE, Jannick, HOPCRAFT, Sharon E, BLIGHT, Keril J, YI, Minkyung, LEMON, Stanley M, BALL, Jonathan K, BUKH, Jens, EVANS, Matthew J
Published in Journal of Virology (01.07.2011)
Published in Journal of Virology (01.07.2011)
Get full text
Journal Article
Structure of the St. Louis Encephalitis Virus Postfusion Envelope Trimer
Luca, Vincent C, Nelson, Christopher A, Fremont, Daved H
Published in Journal of Virology (01.01.2013)
Published in Journal of Virology (01.01.2013)
Get full text
Journal Article
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer
Lim, Jing Shan, Ibaseta, Alvaro, Fischer, Marcus M., Cancilla, Belinda, O’Young, Gilbert, Cristea, Sandra, Luca, Vincent C., Yang, Dian, Jahchan, Nadine S., Hamard, Cécile, Antoine, Martine, Wislez, Marie, Kong, Christina, Cain, Jennifer, Liu, Yu-Wang, Kapoun, Ann M., Garcia, K. Christopher, Hoey, Timothy, Murriel, Christopher L., Sage, Julien
Published in Nature (London) (18.05.2017)
Published in Nature (London) (18.05.2017)
Get full text
Journal Article
LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition
Ming, Qianqian, Celias, Daiana P., Wu, Chao, Cole, Aidan R., Singh, Srishti, Mason, Charlotte, Dong, Shen, Tran, Timothy H., Amarasinghe, Gaya K., Ruffell, Brian, Luca, Vincent C.
Published in Nature immunology (01.07.2022)
Published in Nature immunology (01.07.2022)
Get full text
Journal Article
Discovery of an Orally Bioavailable Small-Molecule Inhibitor for the beta-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction
Wang, Zhen, Zhang, Min, Quereda, Victor, Frydman, Sylvia M., Ming, Qianqian, Luca, Vincent C., Duckett, Derek R., Ji, Haitao
Published in Journal of medicinal chemistry (26.08.2021)
Published in Journal of medicinal chemistry (26.08.2021)
Get full text
Journal Article