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Spangler, Jamie B., Tomala, Jakub, Luca, Vincent C., Jude, Kevin M., Dong, Shen, Ring, Aaron M., Votavova, Petra, Pepper, Marion, Kovar, Marek, Garcia, K. Christopher
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Published in Immunity (Cambridge, Mass.) (19.05.2015)
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Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity
Luca, Vincent C., Kim, Byoung Choul, Ge, Chenghao, Kakuda, Shinako, Wu, Di, Roein-Peikar, Mehdi, Haltiwanger, Robert S., Zhu, Cheng, Ha, Taekjip, Garcia, K. Christopher
Published in Science (American Association for the Advancement of Science) (24.03.2017)
Published in Science (American Association for the Advancement of Science) (24.03.2017)
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The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
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Published in Immunity (Cambridge, Mass.) (08.06.2021)
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Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer
Lim, Jing Shan, Ibaseta, Alvaro, Fischer, Marcus M., Cancilla, Belinda, O’Young, Gilbert, Cristea, Sandra, Luca, Vincent C., Yang, Dian, Jahchan, Nadine S., Hamard, Cécile, Antoine, Martine, Wislez, Marie, Kong, Christina, Cain, Jennifer, Liu, Yu-Wang, Kapoun, Ann M., Garcia, K. Christopher, Hoey, Timothy, Murriel, Christopher L., Sage, Julien
Published in Nature (London) (18.05.2017)
Published in Nature (London) (18.05.2017)
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Structural basis of GPBAR activation and bile acid recognition
Yang, Fan, Mao, Chunyou, Guo, Lulu, Lin, Jingyu, Ming, Qianqian, Xiao, Peng, Wu, Xiang, Shen, Qingya, Guo, Shimeng, Shen, Dan-Dan, Lu, Ruirui, Zhang, Linqi, Huang, Shenming, Ping, Yuqi, Zhang, Chenlu, Ma, Cheng, Zhang, Kai, Liang, Xiaoying, Shen, Yuemao, Nan, Fajun, Yi, Fan, Luca, Vincent C., Zhou, Jiuyao, Jiang, Changtao, Sun, Jin-Peng, Xie, Xin, Yu, Xiao, Zhang, Yan
Published in Nature (London) (19.11.2020)
Published in Nature (London) (19.11.2020)
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Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal
Yan, Kelley S., Janda, Claudia Y., Chang, Junlei, Zheng, Grace X. Y., Larkin, Kathryn A., Luca, Vincent C., Chia, Luis A., Mah, Amanda T., Han, Arnold, Terry, Jessica M., Ootani, Akifumi, Roelf, Kelly, Lee, Mark, Yuan, Jenny, Li, Xiao, Bolen, Christopher R., Wilhelmy, Julie, Davies, Paige S., Ueno, Hiroo, von Furstenberg, Richard J., Belgrader, Phillip, Ziraldo, Solongo B., Ordonez, Heather, Henning, Susan J., Wong, Melissa H., Snyder, Michael P., Weissman, Irving L., Hsueh, Aaron J., Mikkelsen, Tarjei S., Garcia, K. Christopher, Kuo, Calvin J.
Published in Nature (London) (11.05.2017)
Published in Nature (London) (11.05.2017)
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Crystal Structure of the Japanese Encephalitis Virus Envelope Protein
LUCA, Vincent C, ABIMANSOUR, Jad, NELSON, Christopher A, FREMONT, Daved H
Published in Journal of Virology (01.02.2012)
Published in Journal of Virology (01.02.2012)
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Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling
Luca, Vincent C, Miao, Yi, Li, Xingnan, Hollander, Michael J, Kuo, Calvin J, Garcia, K Christopher
Published in PloS one (08.01.2020)
Published in PloS one (08.01.2020)
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Progenitor identification and SARS-CoV-2 infection in human distal lung organoids
Salahudeen, Ameen A., Choi, Shannon S., Rustagi, Arjun, Zhu, Junjie, van Unen, Vincent, de la O, Sean M., Flynn, Ryan A., Margalef-Català, Mar, Santos, António J. M., Ju, Jihang, Batish, Arpit, Usui, Tatsuya, Zheng, Grace X. Y., Edwards, Caitlin E., Wagar, Lisa E., Luca, Vincent, Anchang, Benedict, Nagendran, Monica, Nguyen, Khanh, Hart, Daniel J., Terry, Jessica M., Belgrader, Phillip, Ziraldo, Solongo B., Mikkelsen, Tarjei S., Harbury, Pehr B., Glenn, Jeffrey S., Garcia, K. Christopher, Davis, Mark M., Baric, Ralph S., Sabatti, Chiara, Amieva, Manuel R., Blish, Catherine A., Desai, Tushar J., Kuo, Calvin J.
Published in Nature (London) (24.12.2020)
Published in Nature (London) (24.12.2020)
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Structure of the planar cell polarity cadherins Fat4 and Dachsous1
Medina, Elliot, Easa, Yathreb, Lester, Daniel K., Lau, Eric K., Sprinzak, David, Luca, Vincent C.
Published in Nature communications (16.02.2023)
Published in Nature communications (16.02.2023)
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Notch1 Phase Separation Coupled Percolation facilitates target gene expression and enhancer looping
Foran, Gregory, Hallam, Ryan Douglas, Megaly, Marvel, Turgambayeva, Anel, Antfolk, Daniel, Li, Yifeng, Luca, Vincent C., Necakov, Aleksandar
Published in Scientific reports (19.09.2024)
Published in Scientific reports (19.09.2024)
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LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition
Ming, Qianqian, Celias, Daiana P., Wu, Chao, Cole, Aidan R., Singh, Srishti, Mason, Charlotte, Dong, Shen, Tran, Timothy H., Amarasinghe, Gaya K., Ruffell, Brian, Luca, Vincent C.
Published in Nature immunology (01.07.2022)
Published in Nature immunology (01.07.2022)
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Discovery of an Orally Bioavailable Small-Molecule Inhibitor for the beta-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction
Wang, Zhen, Zhang, Min, Quereda, Victor, Frydman, Sylvia M., Ming, Qianqian, Luca, Vincent C., Duckett, Derek R., Ji, Haitao
Published in Journal of medicinal chemistry (26.08.2021)
Published in Journal of medicinal chemistry (26.08.2021)
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Affinity-matured DLL4 ligands as broad-spectrum modulators of Notch signaling
Gonzalez-Perez, David, Das, Satyajit, Antfolk, Daniel, Ahsan, Hadia S., Medina, Elliot, Dundes, Carolyn E., Jokhai, Rayyan T., Egan, Emily D., Blacklow, Stephen C., Loh, Kyle M., Rodriguez, Paulo C., Luca, Vincent C.
Published in Nature chemical biology (01.01.2023)
Published in Nature chemical biology (01.01.2023)
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Inhibition of Delta-induced Notch signaling using fucose analogs
Schneider, Michael, Kumar, Vivek, Nordstrøm, Lars Ulrik, Feng, Lei, Takeuchi, Hideyuki, Hao, Huilin, Luca, Vincent C, Garcia, K Christopher, Stanley, Pamela, Wu, Peng, Haltiwanger, Robert S
Published in Nature chemical biology (01.01.2018)
Published in Nature chemical biology (01.01.2018)
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Functional Comparison between Endogenous and Synthetic Notch Systems
Khamaisi, Bassma, Luca, Vincent C., Blacklow, Stephen C., Sprinzak, David
Published in ACS synthetic biology (21.10.2022)
Published in ACS synthetic biology (21.10.2022)
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Structural basis for mouse LAG3 interactions with the MHC class II molecule I-Ab
Ming, Qianqian, Antfolk, Daniel, Price, David A., Manturova, Anna, Medina, Elliot, Singh, Srishti, Mason, Charlotte, Tran, Timothy H., Smalley, Keiran S. M., Leung, Daisy W., Luca, Vincent C.
Published in Nature communications (29.08.2024)
Published in Nature communications (29.08.2024)
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Molecular engineering strategies for visualizing low-affinity protein complexes
Ming, Qianqian, Gonzalez-Perez, David, Luca, Vincent C
Published in Experimental biology and medicine (Maywood, N.J.) (01.12.2019)
Published in Experimental biology and medicine (Maywood, N.J.) (01.12.2019)
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