Arylsulfatase K inactivation causes mucopolysaccharidosis due to deficient glucuronate desulfation of heparan and chondroitin sulfate
Trabszo, Christof, Ramms, Bastian, Chopra, Pradeep, Lüllmann-Rauch, Renate, Stroobants, Stijn, Sproß, Jens, Jeschke, Anke, Schinke, Thorsten, Boons, Geert-Jan, Esko, Jeffrey D, Lübke, Torben, Dierks, Thomas
Published in Biochemical journal (18.09.2020)
Published in Biochemical journal (18.09.2020)
Get more information
Journal Article
Heparan Sulfate–Editing Extracellular Sulfatases Enhance VEGF Bioavailability for Ischemic Heart Repair
Korf-Klingebiel, Mortimer, Reboll, Marc R, Grote, Karsten, Schleiner, Hauke, Wang, Yong, Wu, Xuekun, Klede, Stefanie, Mikhed, Yuliya, Bauersachs, Johann, Klintschar, Michael, Rudat, Carsten, Kispert, Andreas, Niessen, Hans W, Lübke, Torben, Dierks, Thomas, Wollert, Kai C
Published in Circulation research (11.10.2019)
Published in Circulation research (11.10.2019)
Get full text
Journal Article
Arylsulfatase G inactivation causes loss of heparan sulfate 3-O-sulfatase activity and mucopolysaccharidosis in mice
Kowalewski, Björn, Lamanna, William C, Lawrence, Roger, Damme, Markus, Stroobants, Stijn, Padva, Michael, Kalus, Ina, Frese, Marc-André, Lübke, Torben, Lüllmann-Rauch, Renate, D’Hooge, Rudi, Esko, Jeffrey D, Dierks, Thomas
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2012)
Get full text
Journal Article
The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for α-secretase activity in fibroblasts
Hartmann, Dieter, de Strooper, Bart, Serneels, Lutgarde, Craessaerts, Katleen, Herreman, An, Annaert, Wim, Umans, Lieve, Lübke, Torben, Lena Illert, Anna, von Figura, Kurt, Saftig, Paul
Published in Human molecular genetics (01.10.2002)
Published in Human molecular genetics (01.10.2002)
Get full text
Journal Article
A novel homozygous missense variant in ARSK causes MPS X, a new subtype of mucopolysaccharidosis
Sun, Miao, Kaminsky, Cornelia K., Deppe, Philip, Ilse, Mai-Britt, Vaz, Frédéric M., Plecko, Barbara, Lübke, Torben, Randolph, Linda M.
Published in Genes & diseases (01.05.2024)
Published in Genes & diseases (01.05.2024)
Get full text
Journal Article
Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1
Pan, Xuefang, Grigoryeva, Lubov, Seyrantepe, Volkan, Peng, Junzheng, Kollmann, Katrin, Tremblay, Johanne, Lavoie, Julie L, Hinek, Aleksander, Lübke, Torben, Pshezhetsky, Alexey V
Published in PLoS genetics (01.02.2014)
Published in PLoS genetics (01.02.2014)
Get full text
Journal Article
Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings
Pan, Xuefang, Wang, Yanting, Lübke, Torben, Hinek, Aleksander, Pshezhetsky, Alexey V
Published in PloS one (24.02.2017)
Published in PloS one (24.02.2017)
Get full text
Journal Article
Mannose 6 Dephosphorylation of Lysosomal Proteins Mediated by Acid Phosphatases Acp2 and Acp5
Georgia Makrypidi, Markus Damme, Sven Müller-Loennies, Maria Trusch, Bernhard Schmidt, Hartmut Schlüter, Joerg Heeren, Torben Lübke, Paul Saftig, Thomas Braulke
Published in Molecular and Cellular Biology (01.02.2012)
Published in Molecular and Cellular Biology (01.02.2012)
Get full text
Journal Article
Arylsulfatase K is the Lysosomal 2‑Sulfoglucuronate Sulfatase
Dhamale, Omkar P, Lawrence, Roger, Wiegmann, Elena M, Shah, Bhahwal A, Al-Mafraji, Kanar, Lamanna, William C, Lübke, Torben, Dierks, Thomas, Boons, Geert-Jan, Esko, Jeffrey D
Published in ACS chemical biology (17.02.2017)
Published in ACS chemical biology (17.02.2017)
Get full text
Journal Article
Sensorimotor and Neurocognitive Dysfunctions Parallel Early Telencephalic Neuropathology in Fucosidosis Mice
Stroobants, Stijn, Wolf, Heike, Callaerts-Vegh, Zsuzsanna, Dierks, Thomas, Lübke, Torben, D'Hooge, Rudi
Published in Frontiers in behavioral neuroscience (12.04.2018)
Published in Frontiers in behavioral neuroscience (12.04.2018)
Get full text
Journal Article
Impaired Lysosomal Trimming of N-Linked Oligosaccharides Leads to Hyperglycosylation of Native Lysosomal Proteins in Mice with α-Mannosidosis
Damme, Markus, Morelle, Willy, Schmidt, Bernhard, Andersson, Claes, Fogh, Jens, Michalski, Jean-Claude, Lübke, Torben
Published in Molecular and Cellular Biology (01.01.2010)
Published in Molecular and Cellular Biology (01.01.2010)
Get full text
Journal Article
Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L
Savalas, Lalu Rudyat Telly, Gasnier, Bruno, Damme, Markus, Lübke, Torben, Wrocklage, Christian, Debacker, Cécile, Jézégou, Adrien, Reinheckel, Thomas, Hasilik, Andrej, Saftig, Paul, Schröder, Bernd
Published in Biochemical journal (01.10.2011)
Published in Biochemical journal (01.10.2011)
Get more information
Journal Article
NCU-G1 is a highly glycosylated integral membrane protein of the lysosome
Schieweck, Oliver, Damme, Markus, Schröder, Bernd, Hasilik, Andrej, Schmidt, Bernhard, Lübke, Torben
Published in Biochemical journal (29.07.2009)
Published in Biochemical journal (29.07.2009)
Get more information
Journal Article
Golgi GDP-fucose Transporter-deficient Mice Mimic Congenital Disorder of Glycosylation IIc/Leukocyte Adhesion Deficiency II
Hellbusch, Christina C., Sperandio, Markus, Frommhold, David, Yakubenia, Sviatlana, Wild, Martin K., Popovici, Diana, Vestweber, Dietmar, Gröne, Hermann-Josef, von Figura, Kurt, Lübke, Torben, Körner, Christian
Published in The Journal of biological chemistry (06.04.2007)
Published in The Journal of biological chemistry (06.04.2007)
Get full text
Journal Article
De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse
Lakomek, Kristina, Dickmanns, Achim, Mueller, Uwe, Kollmann, Katrin, Deuschl, Florian, Berndt, Annette, Lübke, Torben, Ficner, Ralf
Published in Acta crystallographica. Section D, Biological crystallography. (01.03.2009)
Published in Acta crystallographica. Section D, Biological crystallography. (01.03.2009)
Get full text
Journal Article
Identification of novel lysosomal matrix proteins by proteome analysis
Kollmann, Katrin, Mutenda, Kudzai E., Balleininger, Martina, Eckermann, Ellen, von Figura, Kurt, Schmidt, Bernhard, Lübke, Torben
Published in Proteomics (Weinheim) (01.10.2005)
Published in Proteomics (Weinheim) (01.10.2005)
Get full text
Journal Article
Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells
Kong, Xiang Y, Nesset, Cecilie Kasi, Damme, Markus, Løberg, Else-Marit, Lübke, Torben, Mæhlen, Jan, Andersson, Kristin B, Lorenzo, Petra I, Roos, Norbert, Thoresen, G Hege, Rustan, Arild C, Kase, Eili T, Eskild, Winnie
Published in Disease models & mechanisms (01.03.2014)
Published in Disease models & mechanisms (01.03.2014)
Get full text
Journal Article