Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus
Liu, Pengda, Begley, Michael, Michowski, Wojciech, Inuzuka, Hiroyuki, Ginzberg, Miriam, Gao, Daming, Tsou, Peiling, Gan, Wenjian, Papa, Antonella, Kim, Byeong Mo, Wan, Lixin, Singh, Amrik, Zhai, Bo, Yuan, Min, Wang, Zhiwei, Gygi, Steven P., Lee, Tae Ho, Lu, Kun-Ping, Toker, Alex, Pandolfi, Pier Paolo, Asara, John M., Kirschner, Marc W., Sicinski, Piotr, Cantley, Lewis, Wei, Wenyi
Published in Nature (London) (24.04.2014)
Published in Nature (London) (24.04.2014)
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Journal Article
A novel controlled release formulation of the Pin1 inhibitor ATRA to improve liver cancer therapy by simultaneously blocking multiple cancer pathways
Yang, Dayun, Luo, Wensong, Wang, Jichuang, Zheng, Min, Liao, Xin-Hua, Zhang, Nan, Lu, Wenxian, Wang, Long, Chen, Ai-Zheng, Wu, Wen-Guo, Liu, Hekun, Wang, Shi-Bin, Zhou, Xiao Zhen, Lu, Kun Ping
Published in Journal of controlled release (10.01.2018)
Published in Journal of controlled release (10.01.2018)
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Journal Article
Death-Associated Protein Kinase 1 Phosphorylates Pin1 and Inhibits Its Prolyl Isomerase Activity and Cellular Function
Lee, Tae Ho, Chen, Chun-Hau, Suizu, Futoshi, Huang, Pengyu, Schiene-Fischer, Cordelia, Daum, Sebastian, Zhang, Yan Jessie, Goate, Alison, Chen, Ruey-Hwa, Zhou, Xiao Zhen, Lu, Kun Ping
Published in Molecular cell (22.04.2011)
Published in Molecular cell (22.04.2011)
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Journal Article
ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1
Hilton, Benjamin A., Li, Zhengke, Musich, Phillip R., Wang, Hui, Cartwright, Brian M., Serrano, Moises, Zhou, Xiao Zhen, Lu, Kun Ping, Zou, Yue
Published in Molecular cell (01.10.2015)
Published in Molecular cell (01.10.2015)
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Journal Article
The Rab2A GTPase Promotes Breast Cancer Stem Cells and Tumorigenesis via Erk Signaling Activation
Luo, Man-Li, Gong, Chang, Chen, Chun-Hau, Hu, Hai, Huang, Pengyu, Zheng, Min, Yao, Yandan, Wei, Shuo, Wulf, Gerburg, Lieberman, Judy, Zhou, Xiao Zhen, Song, Erwei, Lu, Kun Ping
Published in Cell reports (Cambridge) (07.04.2015)
Published in Cell reports (Cambridge) (07.04.2015)
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Journal Article
MicroRNA-140-5p inhibits hepatocellular carcinoma by directly targeting the unique isomerase Pin1 to block multiple cancer-driving pathways
Yan, Xingxue, Zhu, Zhendong, Xu, Shenmin, Yang, Li-nan, Liao, Xin-Hua, Zheng, Min, Yang, Dayun, Wang, Jichuang, Chen, Dongmei, Wang, Long, Liu, Xiaolong, Liu, Jingfeng, Chen, Ruey-Hwa, Zhou, Xiao Zhen, Lu, Kun Ping, Liu, Hekun
Published in Scientific reports (06.04.2017)
Published in Scientific reports (06.04.2017)
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Journal Article
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-β production
Xia, Weiming, Lu, Pei-Jung, Li, Shi-Hua, Finn, Greg, Sun, Anyang, Nicholson, Linda K, Pastorino, Lucia, Zhou, Xiao Zhen, Balastik, Martin, Lim, Jormay, Lu, Kun Ping, Wulf, Gerburg, Li, Xiaojiang
Published in Nature (23.03.2006)
Published in Nature (23.03.2006)
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Journal Article
Pin1‐Targeted Therapy for Systemic Lupus Erythematosus
Wei, Shuo, Yoshida, Nobuya, Finn, Greg, Kozono, Shingo, Nechama, Morris, Kyttaris, Vasileios C., Zhen Zhou, Xiao, Tsokos, George C., Ping Lu, Kun
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2016)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2016)
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Journal Article
A Cullin3-KLHL20 Ubiquitin Ligase-Dependent Pathway Targets PML to Potentiate HIF-1 Signaling and Prostate Cancer Progression
Yuan, Wei-Chien, Lee, Yu-Ru, Huang, Shiu-Feng, Lin, Yu-Min, Chen, Tzu-Yin, Chung, Hsiang-Ching, Tsai, Chin-Hsien, Chen, Hsin-Yi, Chiang, Cheng-Ta, Lai, Chun-Kai, Lu, Li-Ting, Chen, Chun-Hau, Gu, De-Leung, Pu, Yeong-Shiau, Jou, Yuh-Shan, Lu, Kun Ping, Hsiao, Pei-Wen, Shih, Hsiu-Ming, Chen, Ruey-Hwa
Published in Cancer cell (16.08.2011)
Published in Cancer cell (16.08.2011)
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Journal Article
Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration
Balastik, Martin, Ferraguti, Francesco, Pires-da Silva, André, Lee, Tae Ho, Alvarez-Bolado, Gonzalo, Lu, Kun Ping, Gruss, Peter
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.2008)
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Journal Article
Targeting PIN1 exerts potent antitumor activity in pancreatic ductal carcinoma via inhibiting tumor metastasis
Chen, Linying, Xu, Xiao, Wen, Xinxin, Xu, Shenmin, Wang, Long, Lu, Wenxian, Jiang, Mingting, Huang, Jing, Yang, Dayun, Wang, Jichuang, Zheng, Min, Zhou, Xiao Zhen, Lu, Kun Ping, Liu, Hekun
Published in Cancer science (01.08.2019)
Published in Cancer science (01.08.2019)
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Journal Article
Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular carcinoma
Zheng, Min, Xu, Huijuan, Liao, Xin-Hua, Chen, Champ Peng, Zhang, Arina Li, Lu, Wenxian, Wang, Long, Yang, Dayun, Wang, Jichuang, Liu, Hekun, Zhou, Xiao Zhen, Lu, Kun Ping
Published in Oncotarget (02.05.2017)
Published in Oncotarget (02.05.2017)
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Journal Article
"Tau immunotherapy: Hopes and hindrances"
Shahpasand, Koorosh, Sepehri Shamloo, Alireza, Nabavi, Seyed Massood, Ping Lu, Kun, Zhen Zhou, Xiao
Published in Human vaccines & immunotherapeutics (01.02.2018)
Published in Human vaccines & immunotherapeutics (01.02.2018)
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Journal Article
Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons
Balastik, Martin, Zhou, Xiao Zhen, Alberich-Jorda, Meritxell, Weissova, Romana, Žiak, Jakub, Pazyra-Murphy, Maria F., Cosker, Katharina E., Machonova, Olga, Kozmikova, Iryna, Chen, Chun-Hau, Pastorino, Lucia, Asara, John M., Cole, Adam, Sutherland, Calum, Segal, Rosalind A., Lu, Kun Ping
Published in Cell reports (Cambridge) (27.10.2015)
Published in Cell reports (Cambridge) (27.10.2015)
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Journal Article
Structural Basis for High-Affinity Peptide Inhibition of Human Pin1
Zhang, Yan, Daum, Sebastian, Wildemann, Dirk, Zhou, Xiao Zhen, Verdecia, Mark A, Bowman, Marianne E, Lücke, Christian, Hunter, Tony, Lu, Kun-Ping, Fischer, Gunter, Noel, Joseph P
Published in ACS chemical biology (01.05.2007)
Published in ACS chemical biology (01.05.2007)
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Journal Article
Opposite Regulation of Oligodendrocyte Apoptosis by JNK3 and Pin1 after Spinal Cord Injury
Li, Qi Ming, Tep, Chhavy, Yune, Tae Y, Zhou, Xiao Zhen, Uchida, Takafumi, Lu, Kun Ping, Yoon, Sung Ok
Published in The Journal of neuroscience (01.08.2007)
Published in The Journal of neuroscience (01.08.2007)
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Journal Article