A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models
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Published in Aging cell (01.02.2020)
Published in Aging cell (01.02.2020)
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Autophagy deficiency in neurodevelopmental disorders
Deng, Zhiqiang, Zhou, Xiaoting, Lu, Jia-Hong, Yue, Zhenyu
Published in Cell & bioscience (17.12.2021)
Published in Cell & bioscience (17.12.2021)
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Corni Fructus: a review of chemical constituents and pharmacological activities
Dong, Yu, Feng, Zhe-Ling, Chen, Hu-Biao, Wang, Fu-Sheng, Lu, Jia-Hong
Published in Chinese medicine (25.06.2018)
Published in Chinese medicine (25.06.2018)
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Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models
Zhuang, Xu-Xu, Wang, Sheng-Fang, Tan, Yuan, Song, Ju-Xian, Zhu, Zhou, Wang, Zi-Ying, Wu, Ming-Yue, Cai, Cui-Zan, Huang, Zhi-Jian, Tan, Jie-Qiong, Su, Huan-Xing, Li, Min, Lu, Jia-Hong
Published in Cell death & disease (18.02.2020)
Published in Cell death & disease (18.02.2020)
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Traditional Chinese medicine compounds regulate autophagy for treating neurodegenerative disease: A mechanism review
Wang, Zi-Ying, Liu, Jia, Zhu, Zhou, Su, Cheng-Fu, Sreenivasmurthy, Sravan Gopalkrishnashetty, Iyaswamy, Ashok, Lu, Jia-Hong, Chen, Gang, Song, Ju-Xian, Li, Min
Published in Biomedicine & pharmacotherapy (01.01.2021)
Published in Biomedicine & pharmacotherapy (01.01.2021)
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Natural Alkaloid Compounds as Inhibitors for Alpha-Synuclein Seeded Fibril Formation and Toxicity
Ghanem, Simona S., Fayed, Hend S., Zhu, Qi, Lu, Jia-Hong, Vaikath, Nishant N., Ponraj, Janarthanan, Mansour, Said, El-Agnaf, Omar M. A.
Published in Molecules (Basel, Switzerland) (19.06.2021)
Published in Molecules (Basel, Switzerland) (19.06.2021)
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Enhancement of efferocytosis through biased FPR2 signaling attenuates intestinal inflammation
Wu, Ming‐Yue, Ge, Yun‐Jun, Wang, Er‐Jin, Liao, Qi‐Wen, Ren, Zheng‐Yu, Yu, Yang, Zhu, Guoyuan, Liu, Chun‐Ping, Zhang, Meng‐Ni, Su, Huanxing, Shen, Han‐Ming, Chen, Ye, Wang, Lei, Wang, Yi‐Tao, Li, Min, Bian, Zhaoxiang, Chai, Jin, Ye, Richard D, Lu, Jia‐Hong
Published in EMBO molecular medicine (07.12.2023)
Published in EMBO molecular medicine (07.12.2023)
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Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice
Lachance, Véronik, Wang, Qian, Sweet, Eric, Choi, Insup, Cai, Cui-Zan, Zhuang, Xu-Xu, Zhang, Yuanxi, Jiang, Jessica Li, Blitzer, Robert D, Bozdagi-Gunal, Ozlem, Zhang, Bin, Lu, Jia-Hong, Yue, Zhenyu
Published in Molecular neurodegeneration (27.11.2019)
Published in Molecular neurodegeneration (27.11.2019)
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Cystatin C as a potential therapeutic mediator against Parkinson’s disease via VEGF-induced angiogenesis and enhanced neuronal autophagy in neurovascular units
Zou, Jing, Chen, Zhaoyu, Wei, Xiaobo, Chen, Zhigang, Fu, Yongmei, Yang, Xiaoyan, Chen, Dan, Wang, Rui, Jenner, Peter, Lu, Jia-Hong, Li, Min, Zhang, Zhuohua, Tang, Beisha, Jin, Kunlin, Wang, Qing
Published in Cell death & disease (01.06.2017)
Published in Cell death & disease (01.06.2017)
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Improved in situ characterization of protein complex dynamics at scale with thermal proximity co-aggregation
Sun, Siyuan, Zheng, Zhenxiang, Wang, Jun, Li, Fengming, He, An, Lai, Kunjia, Zhang, Shuang, Lu, Jia-Hong, Tian, Ruijun, Tan, Chris Soon Heng
Published in Nature communications (24.11.2023)
Published in Nature communications (24.11.2023)
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Roles of Nitric Oxide Synthase Isoforms in Neurogenesis
Chong, Cheong-Meng, Ai, Nana, Ke, Minjing, Tan, Yuan, Huang, Zhijian, Li, Yong, Lu, Jia-Hong, Ge, Wei, Su, Huanxing
Published in Molecular neurobiology (01.03.2018)
Published in Molecular neurobiology (01.03.2018)
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Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow
Xie, Chenglong, Zhuang, Xu-Xu, Niu, Zhangming, Ai, Ruixue, Lautrup, Sofie, Zheng, Shuangjia, Jiang, Yinghui, Han, Ruiyu, Gupta, Tanima Sen, Cao, Shuqin, Lagartos-Donate, Maria Jose, Cai, Cui-Zan, Xie, Li-Ming, Caponio, Domenica, Wang, Wen-Wen, Schmauck-Medina, Tomas, Zhang, Jianying, Wang, He-ling, Lou, Guofeng, Xiao, Xianglu, Zheng, Wenhua, Palikaras, Konstantinos, Yang, Guang, Caldwell, Kim A., Caldwell, Guy A., Shen, Han-Ming, Nilsen, Hilde, Lu, Jia-Hong, Fang, Evandro F.
Published in Nature biomedical engineering (01.01.2022)
Published in Nature biomedical engineering (01.01.2022)
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Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease
Dong, Jun, Chen, Li, Ye, Fei, Tang, Junhui, Liu, Bing, Lin, Jiacheng, Zhou, Pang-Hu, Lu, Bin, Wu, Min, Lu, Jia-Hong, He, Jing-Jing, Engelender, Simone, Meng, Qingtao, Song, Zhiyin, He, He
Published in Nature communications (02.01.2024)
Published in Nature communications (02.01.2024)
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Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling
Chong, Cheong-Meng, Ke, Minjing, Tan, Yuan, Huang, Zhijian, Zhang, Ke, Ai, Nana, Ge, Wei, Qin, Dajiang, Lu, Jia-Hong, Su, Huanxing
Published in Cell death & disease (29.08.2018)
Published in Cell death & disease (29.08.2018)
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