Insulin receptor antibody-iduronate 2-sulfatase fusion protein: Pharmacokinetics, anti-drug antibody, and safety pharmacology in Rhesus monkeys
Boado, Ruben J., Ka-Wai Hui, Eric, Zhiqiang Lu, Jeff, Pardridge, William M.
Published in Biotechnology and bioengineering (01.11.2014)
Published in Biotechnology and bioengineering (01.11.2014)
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IgG-single chain Fv fusion protein therapeutic for alzheimer's disease: Expression in CHO cells and pharmacokinetics and brain delivery in the rhesus monkey
Boado, Ruben J, Lu, Jeff Zhiqiang, Hui, Eric Ka-Wai, Pardridge, William M
Published in Biotechnology and bioengineering (15.02.2010)
Published in Biotechnology and bioengineering (15.02.2010)
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Blood-Brain Barrier Molecular Trojan Horse Enables Imaging of Brain Uptake of Radioiodinated Recombinant Protein in the Rhesus Monkey
Boado, Ruben J, Hui, Eric K.-W, Lu, Jeff Zhiqiang, Sumbria, Rachita K, Pardridge, William M
Published in Bioconjugate chemistry (16.10.2013)
Published in Bioconjugate chemistry (16.10.2013)
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Pharmacokinetics and brain uptake in the rhesus monkey of a fusion protein of arylsulfatase a and a monoclonal antibody against the human insulin receptor
Boado, Ruben J., Lu, Jeff Zhiqiang, Hui, Eric K.-W., Sumbria, Rachita K., Pardridge, William M.
Published in Biotechnology and bioengineering (01.05.2013)
Published in Biotechnology and bioengineering (01.05.2013)
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Pharmacokinetics and Brain Uptake of a Genetically Engineered Bifunctional Fusion Antibody Targeting the Mouse Transferrin Receptor
Boado, Ruben J, Zhou, Qing-Hui, Lu, Jeff Zhiqiang, Hui, Eric Ka-Wai, Pardridge, William M
Published in Molecular pharmaceutics (01.02.2010)
Published in Molecular pharmaceutics (01.02.2010)
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Pharmacokinetics and Brain Uptake of an IgG-TNF Decoy Receptor Fusion Protein Following Intravenous, Intraperitoneal, and Subcutaneous Administration in Mice
Sumbria, Rachita K, Zhou, Qing-Hui, Hui, Eric Ka-Wai, Lu, Jeff Zhiqiang, Boado, Ruben J, Pardridge, William M
Published in Molecular pharmaceutics (01.04.2013)
Published in Molecular pharmaceutics (01.04.2013)
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Brain-penetrating IgG-iduronate 2-sulfatase fusion protein for the mouse
Zhou, Qing-Hui, Boado, Ruben J, Lu, Jeff Zhiqiang, Hui, Eric Ka-Wai, Pardridge, William M
Published in Drug metabolism and disposition (01.02.2012)
Published in Drug metabolism and disposition (01.02.2012)
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Receptor-Mediated Abeta Amyloid Antibody Targeting to Alzheimer’s Disease Mouse Brain
Zhou, Qing-Hui, Fu, Ailing, Boado, Ruben J, Hui, Eric Ka-Wai, Lu, Jeff Zhiqiang, Pardridge, William M
Published in Molecular pharmaceutics (07.02.2011)
Published in Molecular pharmaceutics (07.02.2011)
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Journal Article
Structural and Biological Identification of Residues on the Surface of NS3 Helicase Required for Optimal Replication of the Hepatitis C Virus
Mackintosh, Samuel G., Lu, Jeff Zhiqiang, Jordan, John B., Harrison, Melody K., Sikora, Bartek, Sharma, Suresh D., Cameron, Craig E., Raney, Kevin D., Sakon, Joshua
Published in The Journal of biological chemistry (10.02.2006)
Published in The Journal of biological chemistry (10.02.2006)
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Intravenous treatment of experimental Parkinson's disease in the mouse with an IgG-GDNF fusion protein that penetrates the blood–brain barrier
Fu, Ailing, Zhou, Qing-Hui, Hui, Eric Ka-Wai, Lu, Jeff Zhiqiang, Boado, Ruben J, Pardridge, William M
Published in Brain research (17.09.2010)
Published in Brain research (17.09.2010)
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Expression in CHO cells and pharmacokinetics and brain uptake in the Rhesus monkey of an IgG-iduronate-2-sulfatase fusion protein
Lu, Jeff Zhiqiang, Boado, Ruben J., Hui, Eric K.-W., Zhou, Qing-Hui, Pardridge, William M.
Published in Biotechnology and bioengineering (01.08.2011)
Published in Biotechnology and bioengineering (01.08.2011)
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Neuroprotection in experimental stroke in the rat with an IgG–erythropoietin fusion protein
Fu, Ailing, Hui, Eric Ka-Wai, Lu, Jeff Zhiqiang, Boado, Ruben J, Pardridge, William M
Published in Brain research (11.11.2010)
Published in Brain research (11.11.2010)
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