An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease
Horvath, Steve, Gurven, Michael, Levine, Morgan E, Trumble, Benjamin C, Kaplan, Hillard, Allayee, Hooman, Ritz, Beate R, Chen, Brian, Lu, Ake T, Rickabaugh, Tammy M, Jamieson, Beth D, Sun, Dianjianyi, Li, Shengxu, Chen, Wei, Quintana-Murci, Lluis, Fagny, Maud, Kobor, Michael S, Tsao, Philip S, Reiner, Alexander P, Edlefsen, Kerstin L, Absher, Devin, Assimes, Themistocles L
Published in Genome Biology (11.08.2016)
Published in Genome Biology (11.08.2016)
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Journal Article
GrimAge Outperforms Other Epigenetic Clocks in the Prediction of Age-Related Clinical Phenotypes and All-Cause Mortality
McCrory, Cathal, Fiorito, Giovanni, Hernandez, Belinda, Polidoro, Silvia, O'Halloran, Aisling M, Hever, Ann, Ni Cheallaigh, Cliona, Lu, Ake T, Horvath, Steve, Vineis, Paolo, Kenny, Rose Anne
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.05.2021)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.05.2021)
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Journal Article
DNA methylation GrimAge strongly predicts lifespan and healthspan
Lu, Ake T, Quach, Austin, Wilson, James G, Reiner, Alex P, Aviv, Abraham, Raj, Kenneth, Hou, Lifang, Baccarelli, Andrea A, Li, Yun, Stewart, James D, Whitsel, Eric A, Assimes, Themistocles L, Ferrucci, Luigi, Horvath, Steve
Published in Aging (Albany, NY.) (21.01.2019)
Published in Aging (Albany, NY.) (21.01.2019)
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Journal Article
A mammalian methylation array for profiling methylation levels at conserved sequences
Arneson, Adriana, Haghani, Amin, Thompson, Michael J., Pellegrini, Matteo, Kwon, Soo Bin, Vu, Ha, Maciejewski, Emily, Yao, Mingjia, Li, Caesar Z., Lu, Ake T., Morselli, Marco, Rubbi, Liudmilla, Barnes, Bret, Hansen, Kasper D., Zhou, Wanding, Breeze, Charles E., Ernst, Jason, Horvath, Steve
Published in Nature communications (10.02.2022)
Published in Nature communications (10.02.2022)
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Journal Article
An epigenetic biomarker of aging for lifespan and healthspan
Levine, Morgan E, Lu, Ake T, Quach, Austin, Chen, Brian H, Assimes, Themistocles L, Bandinelli, Stefania, Hou, Lifang, Baccarelli, Andrea A, Stewart, James D, Li, Yun, Whitsel, Eric A, Wilson, James G, Reiner, Alex P, Aviv, Abraham, Lohman, Kurt, Liu, Yongmei, Ferrucci, Luigi, Horvath, Steve
Published in Aging (Albany, NY.) (18.04.2018)
Published in Aging (Albany, NY.) (18.04.2018)
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Journal Article
Detection of Macular Ganglion Cell Loss in Glaucoma by Fourier-Domain Optical Coherence Tomography
Tan, Ou, PhD, Chopra, Vikas, MD, Lu, Ake Tzu-Hui, PhD, Schuman, Joel S., MD, Ishikawa, Hiroshi, MD, Wollstein, Gadi, MD, Varma, Rohit, MD, MPH, Huang, David, MD, PhD
Published in Ophthalmology (Rochester, Minn.) (01.12.2009)
Published in Ophthalmology (Rochester, Minn.) (01.12.2009)
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Journal Article
Fundamental equations linking methylation dynamics to maximum lifespan in mammals
Horvath, Steve, Zhang, Joshua, Haghani, Amin, Lu, Ake T., Fei, Zhe
Published in Nature communications (16.09.2024)
Published in Nature communications (16.09.2024)
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Journal Article
Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies
Horvath, Steve, Oshima, Junko, Martin, George M, Lu, Ake T, Quach, Austin, Cohen, Howard, Felton, Sarah, Matsuyama, Mieko, Lowe, Donna, Kabacik, Sylwia, Wilson, James G, Reiner, Alex P, Maierhofer, Anna, Flunkert, Julia, Aviv, Abraham, Hou, Lifang, Baccarelli, Andrea A, Li, Yun, Stewart, James D, Whitsel, Eric A, Ferrucci, Luigi, Matsuyama, Shigemi, Raj, Kenneth
Published in Aging (Albany, NY.) (26.07.2018)
Published in Aging (Albany, NY.) (26.07.2018)
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Journal Article
Menopause accelerates biological aging
Levine, Morgan E., Lu, Ake T., Chen, Brian H., Hernandez, Dena G., Singleton, Andrew B., Ferrucci, Luigi, Bandinelli, Stefania, Salfati, Elias, Manson, JoAnn E., Quach, Austin, Kusters, Cynthia D. J., Kuh, Diana, Wong, Andrew, Teschendorff, Andrew E., Widschwendter, Martin, Ritz, Beate R., Absher, Devin, Assimes, Themistocles L., Horvath, Steve
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2016)
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Journal Article
A meta-analysis of genome-wide association studies of epigenetic age acceleration
Gibson, Jude, Russ, Tom C, Clarke, Toni-Kim, Howard, David M, Hillary, Robert F, Evans, Kathryn L, Walker, Rosie M, Bermingham, Mairead L, Morris, Stewart W, Campbell, Archie, Hayward, Caroline, Murray, Alison D, Porteous, David J, Horvath, Steve, Lu, Ake T, McIntosh, Andrew M, Whalley, Heather C, Marioni, Riccardo E
Published in PLoS genetics (18.11.2019)
Published in PLoS genetics (18.11.2019)
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Journal Article
Epigenetic clock analysis of diet, exercise, education, and lifestyle factors
Quach, Austin, Levine, Morgan E, Tanaka, Toshiko, Lu, Ake T, Chen, Brian H, Ferrucci, Luigi, Ritz, Beate, Bandinelli, Stefania, Neuhouser, Marian L, Beasley, Jeannette M, Snetselaar, Linda, Wallace, Robert B, Tsao, Philip S, Absher, Devin, Assimes, Themistocles L, Stewart, James D, Li, Yun, Hou, Lifang, Baccarelli, Andrea A, Whitsel, Eric A, Horvath, Steve
Published in Aging (Albany, NY.) (14.02.2017)
Published in Aging (Albany, NY.) (14.02.2017)
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Journal Article
Keratoconus Diagnosis with Optical Coherence Tomography Pachymetry Mapping
Li, Yan, PhD, Meisler, David M., MD, Tang, Maolong, PhD, Lu, Ake T.H., PhD, Thakrar, Vishakha, MD, Reiser, Bibiana J., MD, Huang, David, MD, PhD
Published in Ophthalmology (Rochester, Minn.) (01.12.2008)
Published in Ophthalmology (Rochester, Minn.) (01.12.2008)
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Journal Article
Refining epigenetic prediction of chronological and biological age
Bernabeu, Elena, McCartney, Daniel L, Gadd, Danni A, Hillary, Robert F, Lu, Ake T, Murphy, Lee, Wrobel, Nicola, Campbell, Archie, Harris, Sarah E, Liewald, David, Hayward, Caroline, Sudlow, Cathie, Cox, Simon R, Evans, Kathryn L, Horvath, Steve, McIntosh, Andrew M, Robinson, Matthew R, Vallejos, Catalina A, Marioni, Riccardo E
Published in Genome medicine (28.02.2023)
Published in Genome medicine (28.02.2023)
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Journal Article
DNA methylation-based estimator of telomere length
Lu, Ake T, Seeboth, Anne, Tsai, Pei-Chien, Sun, Dianjianyi, Quach, Austin, Reiner, Alex P, Kooperberg, Charles, Ferrucci, Luigi, Hou, Lifang, Baccarelli, Andrea A, Li, Yun, Harris, Sarah E, Corley, Janie, Taylor, Adele, Deary, Ian J, Stewart, James D, Whitsel, Eric A, Assimes, Themistocles L, Chen, Wei, Li, Shengxu, Mangino, Massimo, Bell, Jordana T, Wilson, James G, Aviv, Abraham, Marioni, Riccardo E, Raj, Kenneth, Horvath, Steve
Published in Aging (Albany, NY.) (18.08.2019)
Published in Aging (Albany, NY.) (18.08.2019)
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Journal Article
Epigenetic Age Acceleration Reflects Long-Term Cardiovascular Health
Joyce, Brian T, Gao, Tao, Zheng, Yinan, Ma, Jiantao, Hwang, Shih-Jen, Liu, Lei, Nannini, Drew, Horvath, Steve, Lu, Ake T, Bai Allen, Norrina, Jacobs, Jr, David R, Gross, Myron, Krefman, Amy, Ning, Hongyan, Liu, Kiang, Lewis, Cora E, Schreiner, Pamela J, Sidney, Stephen, Shikany, James M, Levy, Daniel, Greenland, Philip, Hou, Lifang, Lloyd-Jones, Donald
Published in Circulation research (01.10.2021)
Published in Circulation research (01.10.2021)
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