Chemical proteomics reveals new targets of cysteine sulfinic acid reductase
Akter, Salma, Fu, Ling, Jung, Youngeun, Conte, Mauro Lo, Lawson, J. Reed, Lowther, W. Todd, Sun, Rui, Liu, Keke, Yang, Jing, Carroll, Kate S.
Published in Nature chemical biology (01.11.2018)
Published in Nature chemical biology (01.11.2018)
Get full text
Journal Article
Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins
Bolduc, Jesalyn A., Nelson, Kimberly J., Haynes, Alexina C., Lee, Jingyun, Reisz, Julie A., Graff, Aaron H., Clodfelter, Jill E., Parsonage, Derek, Poole, Leslie B., Furdui, Cristina M., Lowther, W. Todd
Published in The Journal of biological chemistry (27.07.2018)
Published in The Journal of biological chemistry (27.07.2018)
Get full text
Journal Article
Substrate specificity and membrane topologies of the iron-containing ω3 and ω6 desaturases from Mortierella alpina
Wang, Mingxuan, Chen, Haiqin, Ailati, Aisikaer, Chen, Wei, Chilton, Floyd H., Todd Lowther, W., Chen, Yong Q.
Published in Applied microbiology and biotechnology (2018)
Published in Applied microbiology and biotechnology (2018)
Get full text
Journal Article
Hydroxyproline Metabolism and Oxalate Synthesis in Primary Hyperoxaluria
Fargue, Sonia, Milliner, Dawn S, Knight, John, Olson, Julie B, Lowther, W Todd, Holmes, Ross P
Published in Journal of the American Society of Nephrology (01.06.2018)
Published in Journal of the American Society of Nephrology (01.06.2018)
Get full text
Journal Article
Cannabinoid Receptor Interacting Protein 1a (CRIP1a): Function and Structure
Booth, William T, Walker, Noah B, Lowther, W Todd, Howlett, Allyn C
Published in Molecules (Basel, Switzerland) (12.10.2019)
Published in Molecules (Basel, Switzerland) (12.10.2019)
Get full text
Journal Article
End Points for Clinical Trials in Primary Hyperoxaluria
Milliner, Dawn S, McGregor, Tracy L, Thompson, Aliza, Dehmel, Bastian, Knight, John, Rosskamp, Ralf, Blank, Melanie, Yang, Sixun, Fargue, Sonia, Rumsby, Gill, Groothoff, Jaap, Allain, Meaghan, West, Melissa, Hollander, Kim, Lowther, W Todd, Lieske, John C
Published in Clinical journal of the American Society of Nephrology (01.07.2020)
Published in Clinical journal of the American Society of Nephrology (01.07.2020)
Get full text
Journal Article
Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria
Summitt, Candice B, Johnson, Lynnette C, Jönsson, Thomas J, Parsonage, Derek, Holmes, Ross P, Lowther, W Todd
Published in Biochemical journal (01.03.2015)
Published in Biochemical journal (01.03.2015)
Get more information
Journal Article
Hydroxyproline metabolism in a mouse model of Primary Hyperoxaluria Type 3
Li, Xingsheng, Knight, John, Todd Lowther, W., Holmes, Ross P.
Published in Biochimica et biophysica acta (01.12.2015)
Published in Biochimica et biophysica acta (01.12.2015)
Get full text
Journal Article
Kinetic analysis of structural influences on the susceptibility of peroxiredoxins 2 and 3 to hyperoxidation
Poynton, Rebecca A, Peskin, Alexander V, Haynes, Alexina C, Lowther, W Todd, Hampton, Mark B, Winterbourn, Christine C
Published in Biochemical journal (15.02.2016)
Published in Biochemical journal (15.02.2016)
Get more information
Journal Article
Mitochondrial peroxiredoxin 3 is more resilient to hyperoxidation than cytoplasmic peroxiredoxins
Cox, Andrew G, Pearson, Andree G, Pullar, Juliet M, Jönsson, Thomas J, Lowther, W Todd, Winterbourn, Christine C, Hampton, Mark B
Published in Biochemical journal (12.06.2009)
Published in Biochemical journal (12.06.2009)
Get more information
Journal Article
The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria
Buchalski, Brianna, Wood, Kyle D., Challa, Anil, Fargue, Sonia, Holmes, Ross P., Lowther, W. Todd, Knight, John
Published in Biochimica et biophysica acta. Molecular basis of disease (01.03.2020)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.03.2020)
Get full text
Journal Article
Cannabinoid receptor interacting protein 1a interacts with myristoylated Gαi N terminus via a unique gapped β-barrel structure
Booth, William T., Clodfelter, Jill E., Leone-Kabler, Sandra, Hughes, Erin K., Eldeeb, Khalil, Howlett, Allyn C., Lowther, W. Todd
Published in The Journal of biological chemistry (01.09.2021)
Published in The Journal of biological chemistry (01.09.2021)
Get full text
Journal Article
Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria
Riedel, Travis J, Johnson, Lynnette C, Knight, John, Hantgan, Roy R, Holmes, Ross P, Lowther, W Todd
Published in PloS one (06.10.2011)
Published in PloS one (06.10.2011)
Get full text
Journal Article
Expression and purification of integral membrane fatty acid desaturases
Chen, Haiqin, Gu, Zhennan, Zhang, Hao, Wang, Mingxuan, Chen, Wei, Lowther, W Todd, Chen, Yong Q
Published in PloS one (08.03.2013)
Published in PloS one (08.03.2013)
Get full text
Journal Article
Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma
Cunniff, Brian, Newick, Kheng, Nelson, Kimberly J, Wozniak, Alexandra N, Beuschel, Stacie, Leavitt, Bruce, Bhave, Anant, Butnor, Kelly, Koenig, Andreas, Chouchani, Edward T, James, Andrew M, Haynes, Alexina C, Lowther, W Todd, Murphy, Michael P, Shukla, Arti, Heintz, Nicholas H
Published in PloS one (26.05.2015)
Published in PloS one (26.05.2015)
Get full text
Journal Article