Neuronal expression of the transcription factor Gli1 using the Tα1 α-tubulin promoter is neuroprotective in an experimental model of Parkinson's disease
Suwelack, D, Hurtado-Lorenzo, A, Millan, E, Gonzalez-Nicolini, V, Wawrowsky, K, Lowenstein, PR, Castro, MG
Published in Gene therapy (01.12.2004)
Published in Gene therapy (01.12.2004)
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Platelets mediate cytotoxic T lymphocyte-induced liver damage
Guidotti, Luca G, Iannacone, Matteo, Sitia, Giovanni, Isogawa, Masanori, Marchese, Patrizia, Castro, Maria G, Lowenstein, Pedro R, Chisari, Francis V, Ruggeri, Zaverio M
Published in Nature medicine (01.11.2005)
Published in Nature medicine (01.11.2005)
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Viral vectors for gene delivery and gene therapy within the endocrine system
Stone, D, David, A, Bolognani, F, Lowenstein, PR, Castro, MG
Published in Journal of endocrinology (01.02.2000)
Published in Journal of endocrinology (01.02.2000)
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Journal Article
There Must Be a Way Out of Here: Identifying a Safe and Efficient Combination of Promoter, Transgene, and Vector Backbone for Gene Therapy of Neurological Disease
Lowenstein, PR, Yadav, Viveka Nand, Chockley, Peter, Castro, Maria
Published in Molecular therapy (01.02.2014)
Published in Molecular therapy (01.02.2014)
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Journal Article
Regulatable Gene Expression Systems for Gene Therapy Applications: Progress and Future Challenges
Goverdhana, S, Puntel, M, Xiong, W, Zirger, J M, Barcia, C, Curtin, J F, Soffer, E B, Mondkar, S, King, G D, Hu, J, Sciascia, S A, Candolfi, M, Greengold, D S, Lowenstein, P R, Castro, M G
Published in Molecular therapy (01.08.2005)
Published in Molecular therapy (01.08.2005)
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Journal Article
Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses
Abordo-Adesida, Evelyn, Follenzi, Antonia, Barcia, Carlos, Sciascia, Sandra, Castro, Maria G, Naldini, Luigi, Lowenstein, Pedro R
Published in Human gene therapy (01.06.2005)
Published in Human gene therapy (01.06.2005)
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Gene transfer into enteric neurons of the rat small intestine in organ culture using a replication defective recombinant herpes simplex virus type 1 (HSV1) vector, but not recombinant adenovirus vectors
BROWN, O. A, SANTER, R. M, SHERING, A. F, LARREGINA, A. T, MORELLI, A. E, SOUTHGATE, T. D, CASTRO, M. G, LOWENSTEIN, P. R
Published in Gene therapy (01.04.1997)
Published in Gene therapy (01.04.1997)
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Plasmacytoid Dendritic Cells in the Tumor Microenvironment: Immune Targets for Glioma Therapeutics
Candolfi, Marianela, King, Gwendalyn D, Yagiz, Kader, Curtin, James F, Mineharu, Yohei, Muhammad, AKM Ghulam, Foulad, David, Kroeger, Kurt M, Barnett, Nick, Josien, Regis, Lowenstein, Pedro R, Castro, Maria G
Published in Neoplasia (New York, N.Y.) (01.08.2012)
Published in Neoplasia (New York, N.Y.) (01.08.2012)
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Kupfer-type immunological synapse characteristics do not predict anti-brain tumor cytolytic T-cell function in vivo
Yang, J, Sanderson, N.S.R, Wawrowsky, K, Puntel, M, Castro, M.G, Lowenstein, P.R
Published in Proceedings of the National Academy of Sciences - PNAS (09.03.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (09.03.2010)
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Peripheral Infection with Adenovirus Causes Unexpected Long-Term Brain Inflammation in Animals Injected Intracranially with First-Generation, but Not with High-Capacity, Adenovirus Vectors: Toward Realistic Long-Term Neurological Gene Therapy for Chronic Diseases
Thomas, Clare E., Schiedner, Gudrun, Kochanek, Stefan, Castro, Maria G., Lowenstein, Pedro R.
Published in Proceedings of the National Academy of Sciences - PNAS (20.06.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (20.06.2000)
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Journal Article
Molecular Indetermination in the Transition to Error Catastrophe: Systematic Elimination of Lymphocytic Choriomeningitis Virus through Mutagenesis Does Not Correlate Linearly with Large Increases in Mutant Spectrum Complexity
Grande-Pérez, A., Sierra, S., Castro, M. G., Domingo, E., Lowenstein, P. R.
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.2002)
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Journal Article
Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model
ALI, Sumia, KING, Gwendalyn D, KUPIEC-WEGLINSKI, Jerzy, VAN ROOIJEN, Nico, LASSMANN, Hans, LOWENSTEIN, Pedro R, CASTRO, Maria G, CURTIN, James F, CANDOLFI, Marianela, WEIDONG XIONG, CHUNYAN LIU, PUNTEL, Mariana, QUENG CHENG, PRIETO, Jesus, RIBAS, Antoni
Published in Cancer research (Chicago, Ill.) (15.08.2005)
Published in Cancer research (Chicago, Ill.) (15.08.2005)
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Journal Article
Current and future strategies for the treatment of malignant brain tumors
Castro, M G, Cowen, R, Williamson, I K, David, A, Jimenez-Dalmaroni, M J, Yuan, X, Bigliari, A, Williams, J C, Hu, J, Lowenstein, P R
Published in Pharmacology & therapeutics (Oxford) (01.04.2003)
Published in Pharmacology & therapeutics (Oxford) (01.04.2003)
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Study of the efficacy, biodistribution, and safety profile of therapeutic gutless adenovirus vectors as a prelude to a phase I clinical trial for glioblastoma
Muhammad, A K M G, Puntel, M, Candolfi, M, Salem, A, Yagiz, K, Farrokhi, C, Kroeger, K M, Xiong, W, Curtin, J F, Liu, C, Lawrence, K, Bondale, N S, Lerner, J, Baker, G J, Foulad, D, Pechnick, R N, Palmer, D, Ng, P, Lowenstein, P R, Castro, M G
Published in Clinical pharmacology and therapeutics (01.08.2010)
Published in Clinical pharmacology and therapeutics (01.08.2010)
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Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: Implications for clinical trials
Castro, M.G, Löwenstein, P.R, Dewey, R. A, Morrissey, G, Cowsill, C. M, Stone, D, Bolognani, F, Dodd, N.J.F, Southgate, T. D, Klatzmann, D, Lassmann, H
Published in Nature medicine (01.11.1999)
Published in Nature medicine (01.11.1999)
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