Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway
Freed-Pastor, William A., Mizuno, Hideaki, Zhao, Xi, Langerød, Anita, Moon, Sung-Hwan, Rodriguez-Barrueco, Ruth, Barsotti, Anthony, Chicas, Agustin, Li, Wencheng, Polotskaia, Alla, Bissell, Mina J., Osborne, Timothy F., Tian, Bin, Lowe, Scott W., Silva, Jose M., Børresen-Dale, Anne-Lise, Levine, Arnold J., Bargonetti, Jill, Prives, Carol
Published in Cell (20.01.2012)
Published in Cell (20.01.2012)
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p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells
Iannello, Alexandre, Thompson, Thornton W, Ardolino, Michele, Lowe, Scott W, Raulet, David H
Published in The Journal of experimental medicine (23.09.2013)
Published in The Journal of experimental medicine (23.09.2013)
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Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
Schneider, William M., Luna, Joseph M., Hoffmann, H.-Heinrich, Sánchez-Rivera, Francisco J., Leal, Andrew A., Ashbrook, Alison W., Le Pen, Jérémie, Ricardo-Lax, Inna, Michailidis, Eleftherios, Peace, Avery, Stenzel, Ansgar F., Lowe, Scott W., MacDonald, Margaret R., Rice, Charles M., Poirier, John T.
Published in Cell (07.01.2021)
Published in Cell (07.01.2021)
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Non-Cell-Autonomous Tumor Suppression by p53
Lujambio, Amaia, Akkari, Leila, Simon, Janelle, Grace, Danielle, Tschaharganeh, Darjus F., Bolden, Jessica E., Zhao, Zhen, Thapar, Vishal, Joyce, Johanna A., Krizhanovsky, Valery, Lowe, Scott W.
Published in Cell (11.04.2013)
Published in Cell (11.04.2013)
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A combinatorial strategy for treating KRAS-mutant lung cancer
Manchado, Eusebio, Weissmueller, Susann, Morris, John P., Chen, Chi-Chao, Wullenkord, Ramona, Lujambio, Amaia, de Stanchina, Elisa, Poirier, John T., Gainor, Justin F., Corcoran, Ryan B., Engelman, Jeffrey A., Rudin, Charles M., Rosen, Neal, Lowe, Scott W.
Published in Nature (London) (30.06.2016)
Published in Nature (London) (30.06.2016)
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NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination
Ruscetti, Marcus, Leibold, Josef, Bott, Matthew J, Fennell, Myles, Kulick, Amanda, Salgado, Nelson R, Chen, Chi-Chao, Ho, Yu-Jui, Sanchez-Rivera, Francisco J, Feucht, Judith, Baslan, Timour, Tian, Sha, Chen, Hsuan-An, Romesser, Paul B, Poirier, John T, Rudin, Charles M, de Stanchina, Elisa, Manchado, Eusebio, Sherr, Charles J, Lowe, Scott W
Published in Science (American Association for the Advancement of Science) (21.12.2018)
Published in Science (American Association for the Advancement of Science) (21.12.2018)
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Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53
Bywater, Megan J., Poortinga, Gretchen, Sanij, Elaine, Hein, Nadine, Peck, Abigail, Cullinane, Carleen, Wall, Meaghan, Cluse, Leonie, Drygin, Denis, Anderes, Kenna, Huser, Nanni, Proffitt, Chris, Bliesath, Joshua, Haddach, Mustapha, Schwaebe, Michael K., Ryckman, David M., Rice, William G., Schmitt, Clemens, Lowe, Scott W., Johnstone, Ricky W., Pearson, Richard B., McArthur, Grant A., Hannan, Ross D.
Published in Cancer cell (10.07.2012)
Published in Cancer cell (10.07.2012)
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A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference
Premsrirut, Prem K., Dow, Lukas E., Kim, Sang Yong, Camiolo, Matthew, Malone, Colin D., Miething, Cornelius, Scuoppo, Claudio, Zuber, Johannes, Dickins, Ross A., Kogan, Scott C., Shroyer, Kenneth R., Sordella, Raffaella, Hannon, Gregory J., Lowe, Scott W.
Published in Cell (01.04.2011)
Published in Cell (01.04.2011)
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Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
Sakamaki, Jun-ichi, Wilkinson, Simon, Hahn, Marcel, Tasdemir, Nilgun, O’Prey, Jim, Clark, William, Hedley, Ann, Nixon, Colin, Long, Jaclyn S., New, Maria, Van Acker, Tim, Tooze, Sharon A., Lowe, Scott W., Dikic, Ivan, Ryan, Kevin M.
Published in Molecular cell (18.05.2017)
Published in Molecular cell (18.05.2017)
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Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening
Sawey, Eric T., Chanrion, Maia, Cai, Chunlin, Wu, Guanming, Zhang, Jianping, Zender, Lars, Zhao, Alice, Busuttil, Ronald W., Yee, Herman, Stein, Lincoln, French, Dorothy M., Finn, Richard S., Lowe, Scott W., Powers, Scott
Published in Cancer cell (08.03.2011)
Published in Cancer cell (08.03.2011)
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Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay
Fellmann, Christof, Zuber, Johannes, McJunkin, Katherine, Chang, Kenneth, Malone, Colin D., Dickins, Ross A., Xu, Qikai, Hengartner, Michael O., Elledge, Stephen J., Hannon, Gregory J., Lowe, Scott W.
Published in Molecular cell (18.03.2011)
Published in Molecular cell (18.03.2011)
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Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer
O'Rourke, Kevin P, Loizou, Evangelia, Livshits, Geulah, Schatoff, Emma M, Baslan, Timour, Manchado, Eusebio, Simon, Janelle, Romesser, Paul B, Leach, Benjamin, Han, Teng, Pauli, Chantal, Beltran, Himisha, Rubin, Mark A, Dow, Lukas E, Lowe, Scott W
Published in Nature biotechnology (01.06.2017)
Published in Nature biotechnology (01.06.2017)
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Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor β signaling
Weissmueller, Susann, Manchado, Eusebio, Saborowski, Michael, Morris, 4th, John P, Wagenblast, Elvin, Davis, Carrie A, Moon, Sung-Hwan, Pfister, Neil T, Tschaharganeh, Darjus F, Kitzing, Thomas, Aust, Daniela, Markert, Elke K, Wu, Jianmin, Grimmond, Sean M, Pilarsky, Christian, Prives, Carol, Biankin, Andrew V, Lowe, Scott W
Published in Cell (10.04.2014)
Published in Cell (10.04.2014)
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Senescence of Activated Stellate Cells Limits Liver Fibrosis
Krizhanovsky, Valery, Yon, Monica, Dickins, Ross A., Hearn, Stephen, Simon, Janelle, Miething, Cornelius, Yee, Herman, Zender, Lars, Lowe, Scott W.
Published in Cell (22.08.2008)
Published in Cell (22.08.2008)
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miR-221 overexpression contributes to liver tumorigenesis
Pineau, Pascal, Volinia, Stefano, McJunkin, Katherine, Marchio, Agnès, Battiston, Carlo, Terris, Benoît, Mazzaferro, Vincenzo, Lowe, Scott W, Croce, Carlo M, Dejean, Anne
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2010)
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Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
Hoffmann, H.-Heinrich, Sánchez-Rivera, Francisco J., Schneider, William M., Luna, Joseph M., Soto-Feliciano, Yadira M., Ashbrook, Alison W., Le Pen, Jérémie, Leal, Andrew A., Ricardo-Lax, Inna, Michailidis, Eleftherios, Hao, Yuan, Stenzel, Ansgar F., Peace, Avery, Zuber, Johannes, Allis, C. David, Lowe, Scott W., MacDonald, Margaret R., Poirier, John T., Rice, Charles M.
Published in Cell Host & Microbe (10.02.2021)
Published in Cell Host & Microbe (10.02.2021)
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A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response
Hoshii, Takayuki, Cifani, Paolo, Feng, Zhaohui, Huang, Chun-Hao, Koche, Richard, Chen, Chun-Wei, Delaney, Christopher D., Lowe, Scott W., Kentsis, Alex, Armstrong, Scott A.
Published in Cell (22.02.2018)
Published in Cell (22.02.2018)
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BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance
Tasdemir, Nilgun, Banito, Ana, Roe, Jae-Seok, Alonso-Curbelo, Direna, Camiolo, Matthew, Tschaharganeh, Darjus F, Huang, Chun-Hao, Aksoy, Ozlem, Bolden, Jessica E, Chen, Chi-Chao, Fennell, Myles, Thapar, Vishal, Chicas, Agustin, Vakoc, Christopher R, Lowe, Scott W
Published in Cancer discovery (01.06.2016)
Published in Cancer discovery (01.06.2016)
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High resolution copy number inference in cancer using short-molecule nanopore sequencing
Baslan, Timour, Kovaka, Sam, Sedlazeck, Fritz J, Zhang, Yanming, Wappel, Robert, Tian, Sha, Lowe, Scott W, Goodwin, Sara, Schatz, Michael C
Published in Nucleic acids research (02.12.2021)
Published in Nucleic acids research (02.12.2021)
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