The tumor suppressor PTEN is exported in exosomes and has phosphatase activity in recipient cells
Putz, Ulrich, Howitt, Jason, Doan, Anh, Goh, Choo-Peng, Low, Ley-Hian, Silke, John, Tan, Seong-Seng
Published in Science signaling (25.09.2012)
Published in Science signaling (25.09.2012)
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Journal Article
Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia
Howitt, Jason, Lackovic, Jenny, Low, Ley-Hian, Naguib, Adam, Macintyre, Alison, Goh, Choo-Peng, Callaway, Jennifer K, Hammond, Vicki, Thomas, Tim, Dixon, Matthew, Putz, Ulrich, Silke, John, Bartlett, Perry, Yang, Baoli, Kumar, Sharad, Trotman, Lloyd C, Tan, Seong-Seng
Published in The Journal of cell biology (09.01.2012)
Published in The Journal of cell biology (09.01.2012)
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Journal Article
Rab5 and Ndfip1 Are Involved in Pten Ubiquitination and Nuclear Trafficking
Li, Yijia, Low, Ley‐Hian, Putz, Ulrich, Goh, Choo‐Peng, Tan, Seong‐Seng, Howitt, Jason
Published in Traffic (Copenhagen, Denmark) (01.07.2014)
Published in Traffic (Copenhagen, Denmark) (01.07.2014)
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Journal Article
Engineered Exosomes as Vehicles for Biologically Active Proteins
Sterzenbach, Ulrich, Putz, Ulrich, Low, Ley-Hian, Silke, John, Tan, Seong-Seng, Howitt, Jason
Published in Molecular therapy (07.06.2017)
Published in Molecular therapy (07.06.2017)
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Journal Article
Bioenergetic state regulates innate inflammatory responses through the transcriptional co-repressor CtBP
Shen, Yiguo, Kapfhamer, David, Minnella, Angela M., Kim, Ji-Eun, Won, Seok Joon, Chen, Yanting, Huang, Yong, Low, Ley Hian, Massa, Stephen M., Swanson, Raymond A.
Published in Nature communications (22.09.2017)
Published in Nature communications (22.09.2017)
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Journal Article
PTEN secretion in exosomes
Putz, Ulrich, Mah, Sophia, Goh, Choo-Peng, Low, Ley-Hian, Howitt, Jason, Tan, Seong-Seng
Published in Methods (San Diego, Calif.) (01.05.2015)
Published in Methods (San Diego, Calif.) (01.05.2015)
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Journal Article
Nedd4 Family Interacting Protein 1 (Ndfip1) Is Required for Ubiquitination and Nuclear Trafficking of BRCA1-associated ATM Activator 1 (BRAT1) during the DNA Damage Response
Low, Ley-Hian, Chow, Yuh-Lit, Li, Yijia, Goh, Choo-Peng, Putz, Ulrich, Silke, John, Ouchi, Toru, Howitt, Jason, Tan, Seong-Seng
Published in The Journal of biological chemistry (13.03.2015)
Published in The Journal of biological chemistry (13.03.2015)
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Journal Article
Ndfip1 expression in developing neurons indicates a role for protein ubiquitination by Nedd4 E3 ligases during cortical development
Goh, Choo-Peng, Low, Ley-Hian, Putz, Ulrich, Gunnersen, Jenny, Hammond, Vicki, Howitt, Jason, Tan, Seong-Seng
Published in Neuroscience letters (25.10.2013)
Published in Neuroscience letters (25.10.2013)
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Journal Article
Ndfip1 represses cell proliferation by controlling Pten localization and signaling specificity
Howitt, Jason, Low, Ley-Hian, Putz, Ulrich, Doan, Anh, Lackovic, Jenny, Goh, Choo-Peng, Gunnersen, Jenny, Silke, John, Tan, Seong-Seng
Published in Journal of molecular cell biology (01.04.2015)
Published in Journal of molecular cell biology (01.04.2015)
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Journal Article
Ndfip1 is required for the development of pyramidal neuron dendrites and spines in the neocortex
Hammond, Vicki E, Gunnersen, Jenny M, Goh, Choo-Peng, Low, Ley-Hian, Hyakumura, Tomoko, Tang, Michelle M, Britto, Joanne M, Putz, Ulrich, Howitt, Jason A, Tan, Seong-Seng
Published in Cerebral cortex (New York, N.Y. 1991) (01.12.2014)
Published in Cerebral cortex (New York, N.Y. 1991) (01.12.2014)
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Journal Article
Mechanisms for the exosomal secretion and transmission of á- synuclein in the brain
Howitt, Jasn, Low, Ley-Hian, Sterzenbach, Ulrich, Tan, Seong-Seng
Published in Journal of extracellular vesicles (01.01.2018)
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Published in Journal of extracellular vesicles (01.01.2018)
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