IL‐3 is essential for ICOS‐L stabilization on mast cells, and sustains the IL‐33‐induced RORγt+ Treg generation via enhanced IL‐6 induction
Drube, Sebastian, Müller, Sylvia, Weber, Franziska, Wegner, Philine, Böttcher‐Loschinski, Romy, Gaestel, Matthias, Hutloff, Andreas, Kamradt, Thomas, Andreas, Nico
Published in Immunology (01.05.2021)
Published in Immunology (01.05.2021)
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Journal Article
Impact of Nrf2 expression in reconstituting T-cells of allogeneic hematopoietic stem cell transplanted patients
Karl, Franziska, Stoll, Andrej, Böttcher-Loschinski, Romy, Böttcher, Martin, Baur, Rebecca, Jacobs, Benedikt, Völkl, Simon, Jitschin, Regina, Rösler, Wolf, Mackensen, Andreas, Mougiakakos, Dimitrios
Published in Leukemia (01.03.2021)
Published in Leukemia (01.03.2021)
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Journal Article
Synergistic lethality in chronic myeloid leukemia - targeting oxidative phosphorylation and unfolded protein response effectively complements tyrosine kinase inhibitor treatment
Häselbarth, Lukas, Gamali, Sara, Saul, Domenica, Krumbholz, Manuela, Böttcher-Loschinski, Romy, Böttcher, Martin, Zou, Deyu, Metzler, Markus, Karow, Axel, Mougiakakos, Dimitrios
Published in BMC cancer (27.11.2023)
Published in BMC cancer (27.11.2023)
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Journal Article
TIGIT signaling and its influence on T cell metabolism and immune cell function in the tumor microenvironment
Jantz-Naeem, Nouria, Böttcher-Loschinski, Romy, Borucki, Katrin, Mitchell-Flack, Marisa, Böttcher, Martin, Schraven, Burkhart, Mougiakakos, Dimitrios, Kahlfuss, Sascha
Published in Frontiers in oncology (17.02.2023)
Published in Frontiers in oncology (17.02.2023)
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Journal Article
IL-3 is essential for ICOS-L stabilization on mast cells, and sustains the IL-33-induced RORγt + T reg generation via enhanced IL-6 induction
Drube, Sebastian, Müller, Sylvia, Weber, Franziska, Wegner, Philine, Böttcher-Loschinski, Romy, Gaestel, Matthias, Hutloff, Andreas, Kamradt, Thomas, Andreas, Nico
Published in Immunology (01.05.2021)
Published in Immunology (01.05.2021)
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Journal Article
CLL-Derived Extracellular Vesicles Impair T-Cell Activation and Foster T-Cell Exhaustion via Multiple Immunological Checkpoints
Böttcher, Martin, Böttcher-Loschinski, Romy, Kahlfuss, Sascha, Aigner, Michael, Gießl, Andreas, Mackensen, Andreas, Schlötzer-Schrehardt, Ursula, Tüting, Thomas, Bruns, Heiko, Mougiakakos, Dimitrios
Published in Cells (Basel, Switzerland) (12.07.2022)
Published in Cells (Basel, Switzerland) (12.07.2022)
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Journal Article
Lipotoxicity as a Barrier for T Cell-Based Therapies
Böttcher-Loschinski, Romy, Rial Saborido, Judit, Böttcher, Martin, Kahlfuss, Sascha, Mougiakakos, Dimitrios
Published in Biomolecules (Basel, Switzerland) (25.08.2022)
Published in Biomolecules (Basel, Switzerland) (25.08.2022)
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Journal Article
Accumulation of T-cell-suppressive PD-L1high extracellular vesicles is associated with GvHD and might impact GvL efficacy
Baur, Rebecca, Karl, Franziska, Böttcher-Loschinski, Romy, Stoll, Andrej, Völkl, Simon, Gießl, Andreas, Flamann, Cindy, Bruns, Heiko, Schlötzer-Schrehardt, Ursula, Böttcher, Martin, Schewe, Denis M, Fischer, Thomas, Jitschin, Regina, Mackensen, Andreas, Mougiakakos, Dimitrios
Published in Journal for immunotherapy of cancer (01.03.2023)
Published in Journal for immunotherapy of cancer (01.03.2023)
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Journal Article
Palmitoylated Proteins on AML-Derived Extracellular Vesicles Promote Myeloid-Derived Suppressor Cell Differentiation via TLR2/Akt/mTOR Signaling
Tohumeken, Sehmus, Baur, Rebecca, Böttcher, Martin, Stoll, Andrej, Loschinski, Romy, Panagiotidis, Konstantinos, Braun, Martina, Saul, Domenica, Völkl, Simon, Baur, Andreas S, Bruns, Heiko, Mackensen, Andreas, Jitschin, Regina, Mougiakakos, Dimitrios
Published in Cancer research (Chicago, Ill.) (01.09.2020)
Published in Cancer research (Chicago, Ill.) (01.09.2020)
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Journal Article
Mesenchymal Stromal Cells Disrupt mTOR‐Signaling and Aerobic Glycolysis During T‐Cell Activation
Böttcher, Martin, D. Hofmann, Andreas, Bruns, Heiko, Haibach, Martina, Loschinski, Romy, Saul, Domenica, Mackensen, Andreas, Le Blanc, Katarina, Jitschin, Regina, Mougiakakos, Dimitrios
Published in Stem cells (Dayton, Ohio) (01.02.2016)
Published in Stem cells (Dayton, Ohio) (01.02.2016)
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Journal Article
Accumulation of T-cell-suppressive PD-L1 high extracellular vesicles is associated with GvHD and might impact GvL efficacy
Baur, Rebecca, Karl, Franziska, Böttcher-Loschinski, Romy, Stoll, Andrej, Völkl, Simon, Gießl, Andreas, Flamann, Cindy, Bruns, Heiko, Schlötzer-Schrehardt, Ursula, Böttcher, Martin, Schewe, Denis M, Fischer, Thomas, Jitschin, Regina, Mackensen, Andreas, Mougiakakos, Dimitrios
Published in Journal for immunotherapy of cancer (01.03.2023)
Published in Journal for immunotherapy of cancer (01.03.2023)
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Journal Article
TAK1 and IKK2, novel mediators of SCF-induced signaling and potential targets for c-Kit-driven diseases
Drube, Sebastian, Weber, Franziska, Göpfert, Christiane, Loschinski, Romy, Rothe, Mandy, Boelke, Franziska, Diamanti, Michaela A, Löhn, Tobias, Ruth, Julia, Schütz, Dagmar, Häfner, Norman, Greten, Florian R, Stumm, Ralf, Hartmann, Karin, Krämer, Oliver H, Dudeck, Anne, Kamradt, Thomas
Published in Oncotarget (06.10.2015)
Published in Oncotarget (06.10.2015)
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Journal Article
Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells
Drube, Sebastian, Weber, Franziska, Loschinski, Romy, Beyer, Mandy, Rothe, Mandy, Rabenhorst, Anja, Göpfert, Christiane, Meininger, Isabel, Diamanti, Michaela A, Stegner, David, Häfner, Norman, Böttcher, Martin, Reinecke, Kirstin, Herdegen, Thomas, Greten, Florian R, Nieswandt, Bernhard, Hartmann, Karin, Krämer, Oliver H, Kamradt, Thomas
Published in Oncotarget (10.03.2015)
Published in Oncotarget (10.03.2015)
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Journal Article