Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity
DeVorkin, Lindsay, Pavey, Nils, Carleton, Gillian, Comber, Alexandra, Ho, Cally, Lim, Junghyun, McNamara, Erin, Huang, Haochu, Kim, Paul, Zacharias, Lauren G., Mizushima, Noboru, Saitoh, Tatsuya, Akira, Shizuo, Beckham, Wayne, Lorzadeh, Alireza, Moksa, Michelle, Cao, Qi, Murthy, Aditya, Hirst, Martin, DeBerardinis, Ralph J., Lum, Julian J.
Published in Cell reports (Cambridge) (09.04.2019)
Published in Cell reports (Cambridge) (09.04.2019)
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Journal Article
Death by HDAC Inhibition in Synovial Sarcoma Cells
Laporte, Aimée N, Poulin, Neal M, Barrott, Jared J, Wang, Xiu Qing, Lorzadeh, Alireza, Vander Werff, Ryan, Jones, Kevin B, Underhill, T Michael, Nielsen, Torsten O
Published in Molecular cancer therapeutics (01.12.2017)
Published in Molecular cancer therapeutics (01.12.2017)
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Journal Article
MicroRNA-708 is a novel regulator of the Hoxa9 program in myeloid cells
Schneider, Edith, Pochert, Nicole, Ruess, Christoph, MacPhee, Liam, Escano, Leo, Miller, Christina, Krowiorz, Kathrin, Delsing Malmberg, Erik, Heravi-Moussavi, Alireza, Lorzadeh, Alireza, Ashouri, Arghavan, Grasedieck, Sarah, Sperb, Nadine, Kumar Kopparapu, Pradeep, Iben, Sebastian, Staffas, Anna, Xiang, Ping, Rösler, Reinhild, Kanduri, Meena, Larsson, Erik, Fogelstrand, Linda, Döhner, Hartmut, Döhner, Konstanze, Wiese, Sebastian, Hirst, Martin, Keith Humphries, R., Palmqvist, Lars, Kuchenbauer, Florian, Rouhi, Arefeh
Published in Leukemia (01.05.2020)
Published in Leukemia (01.05.2020)
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Journal Article
Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia
Kusakabe, Manabu, Sun, Ann Chong, Tyshchenko, Kateryna, Wong, Rachel, Nanda, Aastha, Shanna, Claire, Gusscott, Samuel, Chavez, Elizabeth A., Lorzadeh, Alireza, Zhu, Alice, Hill, Ainsleigh, Hung, Stacy, Brown, Scott, Babaian, Artem, Wang, Xuehai, Holt, Robert A., Steidl, Christian, Karsan, Aly, Humphries, R. Keith, Eaves, Connie J., Hirst, Martin, Weng, Andrew P.
Published in Nature communications (02.07.2019)
Published in Nature communications (02.07.2019)
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Atrophin controls developmental signaling pathways via interactions with Trithorax-like
Yeung, Kelvin, Boija, Ann, Karlsson, Edvin, Holmqvist, Per-Henrik, Tsatskis, Yonit, Nisoli, Ilaria, Yap, Damian, Lorzadeh, Alireza, Moksa, Michelle, Hirst, Martin, Aparicio, Samuel, Fanto, Manolis, Stenberg, Per, Mannervik, Mattias, McNeill, Helen
Published in eLife (22.03.2017)
Published in eLife (22.03.2017)
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Abstract 2456: Distinct metabolic dependencies in pancreatic cancer
Kalaany, Nada, Lee, Min-Sik, Dennis, Courtney, Lorzadeh, Alireza, Hoffman, Megan, Mino-Kenudson, Mari, Dougan, Stephanie, Jadhav, Unmesh, Clish, Clary
Published in The Journal of biological chemistry (2023)
Published in The Journal of biological chemistry (2023)
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Journal Article
Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer
Lee, Min-Sik, Dennis, Courtney, Naqvi, Insia, Dailey, Lucas, Lorzadeh, Alireza, Ye, George, Zaytouni, Tamara, Adler, Ashley, Hitchcock, Daniel S., Lin, Lin, Hoffman, Megan T., Bhuiyan, Aladdin M., Barth, Jaimie L., Machacek, Miranda E., Mino-Kenudson, Mari, Dougan, Stephanie K., Jadhav, Unmesh, Clish, Clary B., Kalaany, Nada Y.
Published in Nature (London) (13.04.2023)
Published in Nature (London) (13.04.2023)
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Abstract PO-028: Pancreatic ductal adenocarcinoma is dependent on an unconventional pathway for polyamine synthesis
Lee, Min-Sik, Naqvi, Insia, Dennis, Courtney, Dailey, Lucas, Lorzadeh, Alireza, Zaytouni, Tamara, Adler, Ashley, Hitchcock, Daniel S., Lin, Lin, Jadhav, Unmesh, Clish, Clary B., Kalaany, Nada Y.
Published in Cancer research (Chicago, Ill.) (15.11.2021)
Published in Cancer research (Chicago, Ill.) (15.11.2021)
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MYC-induced human acute myeloid leukemia requires a continuing IL-3/GM-CSF costimulus
Bulaeva, Elizabeth, Pellacani, Davide, Nakamichi, Naoto, Hammond, Colin A., Beer, Philip A., Lorzadeh, Alireza, Moksa, Michelle, Carles, Annaïck, Bilenky, Misha, Lefort, Sylvain, Shu, Jeremy, Wilhelm, Brian T., Weng, Andrew P., Hirst, Martin, Eaves, Connie J.
Published in Blood (10.12.2020)
Published in Blood (10.12.2020)
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Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity
Giambra, Vincenzo, Gusscott, Samuel, Gracias, Deanne, Song, Raymond, Lam, Sonya H., Panelli, Patrizio, Tyshchenko, Kateryna, Jenkins, Catherine E., Hoofd, Catherine, Lorzadeh, Alireza, Carles, Annaick, Hirst, Martin, Eaves, Connie J., Weng, Andrew P.
Published in Cell stem cell (01.11.2018)
Published in Cell stem cell (01.11.2018)
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Journal Article
Growth Factor-Dependent Activation of a MYC-Induced Latent AML Program in Human Hematopoietic Cells
Bulaeva, Elizabeth, Pellacani, Davide, Nakamichi, Naoto, Beer, Philip, Hammond, Colin, Lorzadeh, Alireza, Moksa, Michelle, Carles, Annaick, Bilenky, Misha, Lefort, Sylvain, Shu, Jeremy, Wilhelm, Brian T., Weng, Andrew P., Hirst, Martin, Eaves, Connie J.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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1032 - PROSPECTIVE ANALYSIS OF THE HUMAN LEUKEMOGENIC PROCESS
Eaves, Connie, Bulaeva, Elizabeth, Knapp, David, Hammond, Colin, Pellacani, Davide, Nakamichi, Naoto, Sloma, Ivan, Lorzadeh, Alireza, Beer, Philip, Wilhelm, Brian, Weng, Andrew, Hirst, Martin
Published in Experimental hematology (01.08.2019)
Published in Experimental hematology (01.08.2019)
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Nucleosome Density ChIP-Seq Identifies Distinct Chromatin Modification Signatures Associated with MNase Accessibility
Lorzadeh, Alireza, Bilenky, Misha, Hammond, Colin, Knapp, David J.H.F., Li, Luolan, Miller, Paul H., Carles, Annaick, Heravi-Moussavi, Alireza, Gakkhar, Sitanshu, Moksa, Michelle, Eaves, Connie J., Hirst, Martin
Published in Cell reports (Cambridge) (15.11.2016)
Published in Cell reports (Cambridge) (15.11.2016)
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Journal Article
Regulatory variation: an emerging vantage point for cancer biology
Li, Luolan, Lorzadeh, Alireza, Hirst, Martin
Published in Wiley interdisciplinary reviews. Systems biology and medicine (01.01.2014)
Published in Wiley interdisciplinary reviews. Systems biology and medicine (01.01.2014)
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Journal Article
Abstract A13: Genome-wide transcriptional analysis of HDAC inhibition-induced apoptosis in synovial sarcoma
Laporte, Aimee N., Poulin, Neal M., Lorzadeh, Alireza, Wang, Xiu Qing, werff, Ryan Vander, Barrott, Jared J., Moska, Michelle, Hughes, Christopher, Morin, Gregg, Jones, Kevin B., Hirst, Martin, Underhill, T. Michael, Nielsen, Torsten O.
Published in Clinical cancer research (15.01.2018)
Published in Clinical cancer research (15.01.2018)
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Journal Article
Synthetic De Novo Modeling of Human T-Cell Acute Lymphoblastic Leukemia Reveals HOXB Genes Drive Expansion of Leukemia Cells-of-Origin and Established Tumor Clones
Kusakabe, Manabu, Sun, Ann Chong, Tyshchenko, Kateryna, Wong, Rachel, Nanda, Aastha, Shanna, Claire, Gusscott, Samuel, Chavez, Elizabeth, Lorzadeh, Alireza, Zhu, Alice, Hill, Ainsleigh, Hung, Stacy, Brown, Scott, Babaian, Artem, Wang, Xuehai, Holt, Robert, Steidl, Christian, Karsan, Aly, Humphries, R. Keith, Eaves, Connie J., Hirst, Martin, Weng, Andrew P.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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