Editorial: Astrocytes, a Kaleidoscope of Diversities, a Pharmacological Horizon
Di Cesare Mannelli, Lorenzo, Ceruti, Stefania, Orellana, Juan A
Published in Frontiers in pharmacology (08.03.2021)
Published in Frontiers in pharmacology (08.03.2021)
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Journal Article
N-aryl-N’-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties
Bozdag, Murat, Poli, Giulio, Angeli, Andrea, Lucarini, Elena, Tuccinardi, Tiziano, Di Cesare Mannelli, Lorenzo, Selleri, Silvia, Ghelardini, Carla, Winum, Jean-Yves, Carta, Fabrizio, Supuran, Claudiu T.
Published in Bioorganic chemistry (01.08.2019)
Published in Bioorganic chemistry (01.08.2019)
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Journal Article
Development of Riluzole Analogs with Improved Use-Dependent Inhibition of Skeletal Muscle Sodium Channels
Farinato, Alessandro, Cavalluzzi, Maria Maddalena, Altamura, Concetta, Campanale, Carmen, Laghetti, Paola, Saltarella, Ilaria, Delre, Pietro, Barbault, Arthur, Tarantino, Nancy, Milani, Gualtiero, Rotondo, Natalie Paola, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Pierno, Sabata, Mangiatordi, Giuseppe Felice, Lentini, Giovanni, Desaphy, Jean-François
Published in ACS medicinal chemistry letters (13.07.2023)
Published in ACS medicinal chemistry letters (13.07.2023)
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Journal Article
Piperazines as nootropic agents: New derivatives of the potent cognition-enhancer DM235 carrying hydrophilic substituents
Martino, Maria Vittoria, Guandalini, Luca, Di Cesare Mannelli, Lorenzo, Menicatti, Marta, Bartolucci, Gianluca, Dei, Silvia, Manetti, Dina, Teodori, Elisabetta, Ghelardini, Carla, Romanelli, Maria Novella
Published in Bioorganic & medicinal chemistry (15.03.2017)
Published in Bioorganic & medicinal chemistry (15.03.2017)
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Journal Article
The Efficacy of Camelina sativa Defatted Seed Meal against Colitis-Induced Persistent Visceral Hypersensitivity: The Relevance of PPAR α Receptor Activation in Pain Relief
Lucarini, Elena, Micheli, Laura, Pagnotta, Eleonora, Toti, Alessandra, Ferrara, Valentina, Ciampi, Clara, Margiotta, Francesco, Martelli, Alma, Testai, Lara, Calderone, Vincenzo, Matteo, Roberto, Suriano, Serafino, Troccoli, Antonio, Pecchioni, Nicola, Manera, Clementina, Mannelli, Lorenzo Di Cesare, Ghelardini, Carla
Published in Nutrients (29.07.2022)
Published in Nutrients (29.07.2022)
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Journal Article
Protective effects of carbonic anhydrase inhibition in brain ischaemia in vitro and in vivo models
Dettori, Ilaria, Fusco, Irene, Bulli, Irene, Gaviano, Lisa, Coppi, Elisabetta, Cherchi, Federica, Venturini, Martina, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Nocentini, Alessio, Supuran, Claudiu T., Pugliese, Anna Maria, Pedata, Felicita
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
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Journal Article
Precision Medicine in Alzheimer's Disease: Investigating Comorbid Common Biological Substrates in the Rat Model of Amyloid Beta-Induced Toxicity
Morgese, Maria Grazia, Bove, Maria, Di Cesare Mannelli, Lorenzo, Schiavone, Stefania, Colia, Anna Laura, Dimonte, Stefania, Mhillaj, Emanuela, Sikora, Vladyslav, Tucci, Paolo, Ghelardini, Carla, Trabace, Luigia
Published in Frontiers in pharmacology (03.01.2022)
Published in Frontiers in pharmacology (03.01.2022)
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Journal Article
Prophylactic role of acetyl-l-carnitine on knee lesions and associated pain in a rat model of osteoarthritis
Bianchi, Enrica, Di Cesare Mannelli, Lorenzo, Menicacci, Cristina, Lorenzoni, Paola, Aglianò, Margherita, Ghelardini, Carla
Published in Life sciences (1973) (13.06.2014)
Published in Life sciences (1973) (13.06.2014)
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Journal Article
Novel formyl peptide receptor (FPR) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis
Crocetti, Letizia, Vergelli, Claudia, Guerrini, Gabriella, Cantini, Niccolò, Kirpotina, Liliya N., Schepetkin, Igor A., Quinn, Mark T., Parisio, Carmen, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Giovannoni, Maria Paola
Published in Bioorganic chemistry (01.07.2020)
Published in Bioorganic chemistry (01.07.2020)
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Journal Article
Synthesis of five and six-membered heterocycles bearing an arylpiperazinylalkyl side chain as orally active antinociceptive agents
Vergelli, Claudia, Ciciani, Giovanna, Cilibrizzi, Agostino, Crocetti, Letizia, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Guerrini, Gabriella, Iacovone, Antonella, Giovannoni, Maria Paola
Published in Bioorganic & medicinal chemistry (01.10.2015)
Published in Bioorganic & medicinal chemistry (01.10.2015)
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Journal Article
Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX)
Fragai, Marco, Comito, Giuseppina, Di Cesare Mannelli, Lorenzo, Gualdani, Roberta, Calderone, Vito, Louka, Alexandra, Richichi, Barbara, Francesconi, Oscar, Angeli, Andrea, Nocentini, Alessio, Gratteri, Paola, Chiarugi, Paola, Ghelardini, Carla, Tadini-Buoninsegni, Francesco, Supuran, Claudiu T, Nativi, Cristina
Published in Journal of medicinal chemistry (09.11.2017)
Published in Journal of medicinal chemistry (09.11.2017)
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Journal Article
Effects of the neutrophil elastase inhibitor EL-17 in rat adjuvant-induced arthritis
Di Cesare Mannelli, Lorenzo, Micheli, Laura, Cinci, Lorenzo, Maresca, Mario, Vergelli, Claudia, Pacini, Alessandra, Quinn, Mark T, Paola Giovannoni, Maria, Ghelardini, Carla
Published in Rheumatology (Oxford, England) (01.07.2016)
Published in Rheumatology (Oxford, England) (01.07.2016)
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Journal Article
Development of a chitosan-derivative micellar formulation to improve celecoxib solubility and bioavailability
Mennini, Natascia, Furlanetto, Sandra, Bragagni, Marco, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Mura, Paola
Published in Drug development and industrial pharmacy (01.11.2014)
Published in Drug development and industrial pharmacy (01.11.2014)
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Journal Article
The H2S-Donor Erucin Exhibits Protective Effects against Vascular Inflammation in Human Endothelial and Smooth Muscle Cells
Martelli, Alma, Piragine, Eugenia, Gorica, Era, Citi, Valentina, Testai, Lara, Pagnotta, Eleonora, Lazzeri, Luca, Pecchioni, Nicola, Ciccone, Valerio, Montanaro, Rosangela, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Brancaleone, Vincenzo, Morbidelli, Lucia, Calderone, Vincenzo
Published in Antioxidants (15.06.2021)
Published in Antioxidants (15.06.2021)
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Journal Article
(E)‑3-Furan-2-yl‑N‑p‑tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation
Arias, Hugo R, Ghelardini, Carla, Lucarini, Elena, Tae, Han-Shen, Yousuf, Arsalan, Marcovich, Irina, Manetti, Dina, Romanelli, Maria Novella, Elgoyhen, Ana Belén, Adams, David J, Di Cesare Mannelli, Lorenzo
Published in ACS chemical neuroscience (04.11.2020)
Published in ACS chemical neuroscience (04.11.2020)
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Journal Article
Novel Analgesic/Anti-Inflammatory Agents: 1,5-Diarylpyrrole Nitrooxyalkyl Ethers and Related Compounds as Cyclooxygenase‑2 Inhibiting Nitric Oxide Donors
Anzini, Maurizio, Di Capua, Angela, Valenti, Salvatore, Brogi, Simone, Rovini, Michele, Giuliani, Germano, Cappelli, Andrea, Vomero, Salvatore, Chiasserini, Luisa, Sega, Alessandro, Poce, Giovanna, Giorgi, Gianluca, Calderone, Vincenzo, Martelli, Alma, Testai, Lara, Sautebin, Lidia, Rossi, Antonietta, Pace, Simona, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Benetti, Veronica, Giordani, Antonio, Anzellotti, Paola, Dovizio, Melania, Patrignani, Paola, Biava, Mariangela
Published in Journal of medicinal chemistry (25.04.2013)
Published in Journal of medicinal chemistry (25.04.2013)
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Journal Article
A Novel Ophthalmic Solution Containing Glicopro ® Complex for the Treatment of Patients with Dry Eye Disease: Results from a Pilot Study
Giannaccare, Giuseppe, Vaccaro, Sabrina, Borselli, Massimiliano, Rossi, Costanza, Carnovale Scalzo, Giovanna, Scalia, Giovanni, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Zerillo, Lucrezia, Polvere, Immacolata, Vito, Pasquale, Zotti, Tiziana, Stilo, Romania, Scorcia, Vincenzo
Published in Journal of clinical medicine (01.03.2024)
Published in Journal of clinical medicine (01.03.2024)
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Journal Article
Involvement of the N/OFQ-NOP system in rat morphine antinociceptive tolerance: Are astrocytes the crossroad?
Micheli, Laura, Lucarini, Elena, Corti, Francesca, Ciccocioppo, Roberto, Calò, Girolamo, Rizzi, Anna, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo
Published in European journal of pharmacology (15.03.2018)
Published in European journal of pharmacology (15.03.2018)
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Journal Article