Novel analgesic/anti-inflammatory agents: 1,5-Diarylpyrrole nitrooxyethyl sulfides and related compounds as Cyclooxygenase-2 inhibitors containing a nitric oxide donor moiety endowed with vasorelaxant properties
Saletti, Mario, Maramai, Samuele, Reale, Annalisa, Paolino, Marco, Brogi, Simone, Di Capua, Angela, Cappelli, Andrea, Giorgi, Gianluca, D'Avino, Danilo, Rossi, Antonietta, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Sardella, Roccaldo, Carotti, Andrea, Woelkart, Gerald, Klösch, Burkhard, Bigogno, Chiara, Dondio, Giulio, Anzini, Maurizio
Published in European journal of medicinal chemistry (05.11.2022)
Published in European journal of medicinal chemistry (05.11.2022)
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Journal Article
Design, synthesis and biological evaluation of 7-substituted 4-phenyl-6H-imidazo[1,5-a]thieno[3,2-f] [1,4]diazepines as safe anxiolytic agents
Di Capua, Angela, Reale, Annalisa, Paolino, Marco, Chemi, Giulia, Brogi, Simone, Cappelli, Andrea, Giorgi, Gianluca, Grande, Fedora, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Matucci, Rosanna, Garofalo, Antonio, Anzini, Maurizio
Published in European journal of medicinal chemistry (15.08.2020)
Published in European journal of medicinal chemistry (15.08.2020)
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Journal Article
Retraction Note: Astragali radix: could it be an adjuvant for oxaliplatin-induced neuropathy?
Di Cesare Mannelli, Lorenzo, Pacini, Alessandra, Micheli, Laura, Femia, Angelo Pietro, Maresca, Mario, Zanardelli, Matteo, Vannacci, Alfredo, Gallo, Eugenia, Bilia, Anna Rita, Caderni, Giovanna, Firenzuoli, Fabio, Mugelli, Alessandro, Ghelardini, Carla
Published in Scientific reports (20.06.2023)
Published in Scientific reports (20.06.2023)
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Journal Article
Anti-neuropathic effects of Rosmarinus officinalis L. terpenoid fraction: relevance of nicotinic receptors
Di Cesare Mannelli, Lorenzo, Micheli, Laura, Maresca, Mario, Cravotto, Giancarlo, Bellumori, Maria, Innocenti, Marzia, Mulinacci, Nadia, Ghelardini, Carla
Published in Scientific reports (07.10.2016)
Published in Scientific reports (07.10.2016)
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Journal Article
Extra virgin olive oil and related by-products ( L.) as natural sources of phenolic compounds for abdominal pain relief in gastrointestinal disorders in rats
Parisio, Carmen, Lucarini, Elena, Micheli, Laura, Toti, Alessandra, Bellumori, Maria, Cecchi, Lorenzo, Calosi, Laura, Bani, Daniele, Di Cesare Mannelli, Lorenzo, Mulinacci, Nadia, Ghelardini, Carla
Published in Food & function (01.12.2020)
Published in Food & function (01.12.2020)
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Journal Article
The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis
Arena, Chiara, Gado, Francesca, Di Cesare Mannelli, Lorenzo, Cervetto, Chiara, Carpi, Sara, Reynoso-Moreno, Ines, Polini, Beatrice, Vallini, Erika, Chicca, Stefano, Lucarini, Elena, Bertini, Simone, D’Andrea, Felicia, Digiacomo, Maria, Poli, Giulio, Tuccinardi, Tiziano, Macchia, Marco, Gertsch, Jürg, Marcoli, Manuela, Nieri, Paola, Ghelardini, Carla, Chicca, Andrea, Manera, Clementina
Published in European journal of medicinal chemistry (15.12.2020)
Published in European journal of medicinal chemistry (15.12.2020)
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Journal Article
Effects of Hypericum perforatum extract on oxaliplatin-induced neurotoxicity: in vitro evaluations
Cinci, Lorenzo, Di Cesare Mannelli, Lorenzo, Maidecchi, Anna, Mattoli, Luisa, Ghelardini, Carla
Published in Zeitschrift für Naturforschung C. A journal of biosciences (01.05.2017)
Published in Zeitschrift für Naturforschung C. A journal of biosciences (01.05.2017)
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Journal Article
Anti-inflammatory Effects of Novel P2X4 Receptor Antagonists, NC-2600 and NP-1815-PX, in a Murine Model of Colitis
D'Antongiovanni, Vanessa, Pellegrini, Carolina, Benvenuti, Laura, Fornai, Matteo, Di Salvo, Clelia, Natale, Gianfranco, Ryskalin, Larisa, Bertani, Lorenzo, Lucarini, Elena, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Nemeth, Zoltan H, Haskó, György, Antonioli, Luca
Published in Inflammation (01.08.2022)
Published in Inflammation (01.08.2022)
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Journal Article
Correction: VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoclonal antibody
Micheli, Laura, Parisio, Carmen, Lucarini, Elena, Vona, Alessia, Toti, Alessandra, Pacini, Alessandra, Mello, Tommaso, Boccella, Serena, Ricciardi, Flavia, Maione, Sabatino, Graziani, Grazia, Lacal, Pedro Miguel, Failli, Paola, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo
Published in Journal of experimental & clinical cancer research (23.04.2024)
Published in Journal of experimental & clinical cancer research (23.04.2024)
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Journal Article
Searching for Novel Sources of Hydrogen Sulfide Donors: Chemical Profiling of Polycarpa aurata Extract and Evaluation of the Anti-Inflammatory Effects
Casertano, Marcello, Esposito, Erika, Bello, Ivana, Indolfi, Chiara, Putra, Masteria Yunovilsa, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Menna, Marialuisa, Sorrentino, Raffaella, Cirino, Giuseppe, d'Emmanuele di Villa Bianca, Roberta, Imperatore, Concetta, Panza, Elisabetta, Mitidieri, Emma
Published in Marine drugs (15.12.2023)
Published in Marine drugs (15.12.2023)
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Journal Article
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity
Di Capua, Angela, Sticozzi, Claudia, Brogi, Simone, Brindisi, Margherita, Cappelli, Andrea, Sautebin, Lidia, Rossi, Antonietta, Pace, Simona, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Valacchi, Giuseppe, Giorgi, Gianluca, Giordani, Antonio, Poce, Giovanna, Biava, Mariangela, Anzini, Maurizio
Published in European journal of medicinal chemistry (15.02.2016)
Published in European journal of medicinal chemistry (15.02.2016)
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Journal Article
A TRPA1 antagonist reverts oxaliplatin-induced neuropathic pain
Nativi, Cristina, Gualdani, Roberta, Dragoni, Elisa, Di Cesare Mannelli, Lorenzo, Sostegni, Silvia, Norcini, Martina, Gabrielli, Gabriele, la Marca, Giancarlo, Richichi, Barbara, Francesconi, Oscar, Moncelli, Maria Rosa, Ghelardini, Carla, Roelens, Stefano
Published in Scientific reports (18.06.2013)
Published in Scientific reports (18.06.2013)
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Journal Article
Photobiomodulation therapy by NIR laser in persistent pain: an analytical study in the rat
Micheli, Laura, Di Cesare Mannelli, Lorenzo, Lucarini, Elena, Cialdai, Francesca, Vignali, Leonardo, Ghelardini, Carla, Monici, Monica
Published in Lasers in medical science (01.11.2017)
Published in Lasers in medical science (01.11.2017)
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Journal Article
Beneficial Effect of H2S-Releasing Molecules in an In Vitro Model of Sarcopenia: Relevance of Glucoraphanin
Micheli, Laura, Mitidieri, Emma, Turnaturi, Carlotta, Vanacore, Domenico, Ciampi, Clara, Lucarini, Elena, Cirino, Giuseppe, Ghelardini, Carla, Sorrentino, Raffaella, Di Cesare Mannelli, Lorenzo, d’Emmanuele di Villa Bianca, Roberta
Published in International journal of molecular sciences (25.05.2022)
Published in International journal of molecular sciences (25.05.2022)
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Journal Article
In Vitro Evidence for the Use of Astragali Radix Extracts as Adjuvant against Oxaliplatin-Induced Neurotoxicity
Di Cesare Mannelli, Lorenzo, Zanardelli, Matteo, Bartolucci, Gianluca, Karioti, Anastasia, Bilia, Anna Rita, Vannacci, Alfredo, Mugelli, Alessandro, Ghelardini, Carla
Published in Planta medica (01.08.2015)
Published in Planta medica (01.08.2015)
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Journal Article
Apoptotic Process Induced by Oxaliplatin in Rat Hippocampus Causes Memory Impairment
Bianchi, Enrica, Di Cesare Mannelli, Lorenzo, Micheli, Laura, Farzad, Mersedez, Aglianò, Margherita, Ghelardini, Carla
Published in Basic & clinical pharmacology & toxicology (01.01.2017)
Published in Basic & clinical pharmacology & toxicology (01.01.2017)
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Journal Article
Design, Synthesis, and X‑ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology
Angeli, Andrea, di Cesare Mannelli, Lorenzo, Trallori, Elena, Peat, Thomas S, Ghelardini, Carla, Carta, Fabrizio, Supuran, Claudiu T
Published in ACS medicinal chemistry letters (10.05.2018)
Published in ACS medicinal chemistry letters (10.05.2018)
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Journal Article
Oxaliplatin-Induced Neuropathy: Genetic and Epigenetic Profile to Better Understand How to Ameliorate This Side Effect
Branca, Jacopo Junio Valerio, Carrino, Donatello, Gulisano, Massimo, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Pacini, Alessandra
Published in Frontiers in molecular biosciences (07.05.2021)
Published in Frontiers in molecular biosciences (07.05.2021)
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Journal Article
Nociceptin/orphanin FQ receptor and pain: Feasibility of the fourth opioid family member
Di Cesare Mannelli, Lorenzo, Micheli, Laura, Ghelardini, Carla
Published in European journal of pharmacology (05.11.2015)
Published in European journal of pharmacology (05.11.2015)
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Journal Article