The atypical antipsychotic olanzapine causes weight gain by targeting serotonin receptor 2C
Lord, Caleb C, Wyler, Steven C, Wan, Rong, Castorena, Carlos M, Ahmed, Newaz, Mathew, Dias, Lee, Syann, Liu, Chen, Elmquist, Joel K
Published in The Journal of clinical investigation (01.09.2017)
Published in The Journal of clinical investigation (01.09.2017)
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Journal Article
Serotonergic Control of Metabolic Homeostasis
Wyler, Steven C, Lord, Caleb C, Lee, Syann, Elmquist, Joel K, Liu, Chen
Published in Frontiers in cellular neuroscience (20.09.2017)
Published in Frontiers in cellular neuroscience (20.09.2017)
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Journal Article
POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels
Caron, Alexandre, Dungan Lemko, Heather M, Castorena, Carlos M, Fujikawa, Teppei, Lee, Syann, Lord, Caleb C, Ahmed, Newaz, Lee, Charlotte E, Holland, William L, Liu, Chen, Elmquist, Joel K
Published in eLife (12.03.2018)
Published in eLife (12.03.2018)
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Journal Article
Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity
Schreiber, Renate, Hofer, Peter, Taschler, Ulrike, Voshol, Peter J., Rechberger, Gerald N., Kotzbeck, Petra, Jaeger, Doris, Preiss-Landl, Karina, Lord, Caleb C., Brown, J. Mark, Haemmerle, Guenter, Zimmermann, Robert, Vidal-Puig, Antonio, Zechner, Rudolf
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2015)
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Journal Article
Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation
Lord, Caleb C., Ferguson, Daniel, Thomas, Gwynneth, Brown, Amanda L., Schugar, Rebecca C., Burrows, Amy, Gromovsky, Anthony D., Betters, Jenna, Neumann, Chase, Sacks, Jessica, Marshall, Stephanie, Watts, Russell, Schweiger, Martina, Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Lathia, Justin D., Sakaguchi, Takuya F., Lehner, Richard, Haemmerle, Guenter, Zechner, Rudolf, Brown, J. Mark
Published in Cell reports (Cambridge) (26.07.2016)
Published in Cell reports (Cambridge) (26.07.2016)
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Journal Article
Assessing human carcinogenicity risk of agrochemicals without the rodent cancer bioassay
Goetz, Amber, Ryan, Natalia, Sauve-Ciencewicki, Alaina, Lord, Caleb C, Hilton, Gina M, Wolf, Douglas C
Published in Frontiers in toxicology (12.06.2024)
Published in Frontiers in toxicology (12.06.2024)
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Journal Article
Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease
Jia, Lin, Chang, Xiuli, Qian, Shuwen, Liu, Chen, Lord, Caleb C., Ahmed, Newaz, Lee, Charlotte E., Lee, Syann, Gautron, Laurent, Mitchell, Mack C., Horton, Jay D., Scherer, Philipp E., Elmquist, Joel K.
Published in Molecular metabolism (Germany) (01.08.2018)
Published in Molecular metabolism (Germany) (01.08.2018)
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Journal Article
Gαi/o-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents
Yoo, Eun-Seon, Li, Li, Jia, Lin, Lord, Caleb C., Lee, Charlotte E., Birnbaum, Shari G., Vianna, Claudia R., Berglund, Eric D., Cunningham, Kathryn A., Xu, Yong, Sohn, Jong-Woo, Liu, Chen
Published in Cell reports (Cambridge) (16.11.2021)
Published in Cell reports (Cambridge) (16.11.2021)
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Journal Article
Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis[S]
Goeritzer, Madeleine, Schlager, Stefanie, Radovic, Branislav, Madreiter, Corina T., Rainer, Silvia, Thomas, Gwynneth, Lord, Caleb C., Sacks, Jessica, Brown, Amanda L., Vujic, Nemanja, Obrowsky, Sascha, Sachdev, Vinay, Kolb, Dagmar, Chandak, Prakash G., Graier, Wolfgang F., Sattler, Wolfgang, Brown, J. Mark, Kratky, Dagmar
Published in Journal of lipid research (01.12.2014)
Published in Journal of lipid research (01.12.2014)
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Journal Article
Adipose-selective overexpression of ABHD5/CGI-58 does not increase lipolysis or protect against diet-induced obesity
Caviglia, Jorge M., Betters, Jenna L., Dapito, Dianne-Helerie, Lord, Caleb C., Sullivan, Sean, Chua, Streamson, Yin, Terry, Sekowski, Anna, Mu, Haiyan, Shapiro, Lawrence, Brown, J. Mark, Brasaemle, Dawn L.
Published in Journal of lipid research (01.11.2011)
Published in Journal of lipid research (01.11.2011)
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Journal Article
Acyl-ghrelin Is Permissive for the Normal Counterregulatory Response to Insulin-Induced Hypoglycemia
Shankar, Kripa, Gupta, Deepali, Mani, Bharath K, Findley, Brianna G, Lord, Caleb C, Osborne-Lawrence, Sherri, Metzger, Nathan P, Pietra, Claudio, Liu, Chen, Berglund, Eric D, Zigman, Jeffrey M
Published in Diabetes (New York, N.Y.) (01.02.2020)
Published in Diabetes (New York, N.Y.) (01.02.2020)
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Journal Article
Ghrelin Receptor Agonist Rescues Excess Neonatal Mortality in a Prader-Willi Syndrome Mouse Model
Rodriguez, Juan A, Bruggeman, Emily C, Mani, Bharath K, Osborne-Lawrence, Sherri, Lord, Caleb C, Roseman, Henry F, Viroslav, Hannah L, Vijayaraghavan, Prasanna, Metzger, Nathan P, Gupta, Deepali, Shankar, Kripa, Pietra, Claudio, Liu, Chen, Zigman, Jeffrey M
Published in Endocrinology (Philadelphia) (01.12.2018)
Published in Endocrinology (Philadelphia) (01.12.2018)
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Journal Article
The Serine Hydrolase ABHD6 Is a Critical Regulator of the Metabolic Syndrome
Thomas, Gwynneth, Betters, Jenna L., Lord, Caleb C., Brown, Amanda L., Marshall, Stephanie, Ferguson, Daniel, Sawyer, Janet, Davis, Matthew A., Melchior, John T., Blume, Lawrence C., Howlett, Allyn C., Ivanova, Pavlina T., Milne, Stephen B., Myers, David S., Mrak, Irina, Leber, Vera, Heier, Christoph, Taschler, Ulrike, Blankman, Jacqueline L., Cravatt, Benjamin F., Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Zimmermann, Robert, Brown, H. Alex, Brown, J. Mark
Published in Cell reports (Cambridge) (01.10.2013)
Published in Cell reports (Cambridge) (01.10.2013)
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Journal Article
CGI-58/ABHD5-Derived Signaling Lipids Regulate Systemic Inflammation and Insulin Action
LORD, Caleb C, BETTERS, Jenna L, LEE, Richard G, CROOKE, Rosanne M, GRAHAM, Mark J, PARKS, John S, BRASAEMLE, Dawn L, FESSLER, Michael B, BROWN, H. Alex, BROWN, J. Mark, IVANOVA, Pavlina T, MILNE, Stephen B, MYERS, David S, MADENSPACHER, Jennifer, THOMAS, Gwynneth, CHUNG, Soonkyu, MINGXIA LIU, DAVIS, Matthew A
Published in Diabetes (New York, N.Y.) (01.02.2012)
Published in Diabetes (New York, N.Y.) (01.02.2012)
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Journal Article
CGI-58’S ABILITY TO REGULATE HEPATIC TRIACYLGLYCEROL METABOLISM DOES NOT REQUIRE ATGL CO-ACTIVATION
Lord, Caleb C., Ferguson, Daniel, Thomas, Gwynneth, Brown, Amanda L., Schugar, Rebecca C., Burrows, Amy, Gromovsky, Anthony D., Betters, Jenna, Neumann, Chase, Sacks, Jessica, Marshall, Stephanie, Watts, Russell, Schweiger, Martina, Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Lathia, Justin D., Sakaguchi, Takuya F., Lehner, Richard, Haemmerle, Guenter, Zechner, Rudolf, Brown, J. Mark
Published in Cell reports (Cambridge) (07.07.2016)
Published in Cell reports (Cambridge) (07.07.2016)
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Journal Article