Metabolic subtypes of patients with NAFLD exhibit distinctive cardiovascular risk profiles
Martínez‐Arranz, Ibon, Bruzzone, Chiara, Noureddin, Mazen, Gil‐Redondo, Ruben, Mincholé, Itziar, Bizkarguenaga, Maider, Arretxe, Enara, Iruarrizaga‐Lejarreta, Marta, Fernández‐Ramos, David, Lopitz‐Otsoa, Fernando, Mayo, Rebeca, Embade, Nieves, Newberry, Elizabeth, Mittendorf, Bettina, Izquierdo‐Sánchez, Laura, Smid, Vaclav, Arnold, Jorge, Iruzubieta, Paula, Pérez Castaño, Ylenia, Krawczyk, Marcin, Marigorta, Urko M., Morrison, Martine C., Kleemann, Robert, Martín‐Duce, Antonio, Hayardeny, Liat, Vitek, Libor, Bruha, Radan, Aller de la Fuente, Rocío, Crespo, Javier, Romero‐Gomez, Manuel, Banales, Jesus M, Arrese, Marco, Cusi, Kenneth, Bugianesi, Elisabetta, Klein, Samuel, Lu, Shelly C., Anstee, Quentin M., Millet, Oscar, Davidson, Nicholas O., Alonso, Cristina, Mato, José M.
Published in Hepatology (Baltimore, Md.) (01.10.2022)
Published in Hepatology (Baltimore, Md.) (01.10.2022)
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Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease
Barbier-Torres, Lucía, Murray, Ben, Yang, Jin Won, Wang, Jiaohong, Matsuda, Michitaka, Robinson, Aaron, Binek, Aleksandra, Fan, Wei, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Luque-Urbano, Maria, Millet, Oscar, Mavila, Nirmala, Peng, Hui, Ramani, Komal, Gottlieb, Roberta, Sun, Zhaoli, Liangpunsakul, Suthat, Seki, Ekihiro, Van Eyk, Jennifer E, Mato, Jose M, Lu, Shelly C
Published in Nature communications (28.01.2022)
Published in Nature communications (28.01.2022)
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Deregulated neddylation in liver fibrosis
Zubiete‐Franco, Imanol, Fernández‐Tussy, Pablo, Barbier‐Torres, Lucía, Simon, Jorge, Fernández‐Ramos, David, Lopitz‐Otsoa, Fernando, Gutiérrez‐de Juan, Virginia, de Davalillo, Sergio López, Duce, Antonio Martín, Iruzubieta, Paula, Taibo, Daniel, Crespo, Javier, Caballeria, Juan, Villa, Erica, Aurrekoetxea, Igor, Aspichueta, Patricia, Varela‐Rey, Marta, Lu, Shelly C, Mato, José M., Beraza, Naiara, Delgado, Teresa C., Martínez‐Chantar, María L
Published in Hepatology (Baltimore, Md.) (01.02.2017)
Published in Hepatology (Baltimore, Md.) (01.02.2017)
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Multi-Omics Integration Highlights the Role of Ubiquitination in CCl4-Induced Liver Fibrosis
Mercado-Gómez, Maria, Lopitz-Otsoa, Fernando, Azkargorta, Mikel, Serrano-Maciá, Marina, Lachiondo-Ortega, Sofia, Goikoetxea-Usandizaga, Naroa, Rodríguez-Agudo, Rubén, Fernández-Ramos, David, Bizkarguenaga, Maider, Juan, Virginia Gutiérrez-de, Lectez, Benoît, Aloria, Kerman, Arizmendi, Jesus M., Simon, Jorge, Alonso, Cristina, Lozano, Juan J., Avila, Matias A., Banales, Jesus M., Marin, Jose J. G., Beraza, Naiara, Mato, José M., Elortza, Félix, Barrio, Rosa, Sutherland, James D., Mayor, Ugo, Martínez-Chantar, María L., Delgado, Teresa C.
Published in International journal of molecular sciences (01.12.2020)
Published in International journal of molecular sciences (01.12.2020)
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Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin‐1
Barbier‐Torres, Lucía, Beraza, Naiara, Fernández‐Tussy, Pablo, Lopitz‐Otsoa, Fernando, Fernández‐Ramos, David, Zubiete‐Franco, Imanol, Varela‐Rey, Marta, Delgado, Teresa C., Gutiérrez, Virginia, Anguita, Juan, Pares, Albert, Banales, Jesús M., Villa, Erica, Caballería, Juan, Alvarez, Luis, Lu, Shelly C., Mato, Jose M., Martínez‐Chantar, María Luz
Published in Hepatology (Baltimore, Md.) (01.10.2015)
Published in Hepatology (Baltimore, Md.) (01.10.2015)
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SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of Serum
Bruzzone, Chiara, Bizkarguenaga, Maider, Gil-Redondo, Rubén, Diercks, Tammo, Arana, Eunate, García de Vicuña, Aitor, Seco, Marisa, Bosch, Alexandre, Palazón, Asís, San Juan, Itxaso, Laín, Ana, Gil-Martínez, Jon, Bernardo-Seisdedos, Ganeko, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Embade, Nieves, Lu, Shelly, Mato, José M., Millet, Oscar
Published in iScience (23.10.2020)
Published in iScience (23.10.2020)
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O-GlcNAcylated p53 in the liver modulates hepatic glucose production
Gonzalez-Rellan, Maria J, Fondevila, Marcos F, Fernandez, Uxia, Rodríguez, Amaia, Varela-Rey, Marta, Veyrat-Durebex, Christelle, Seoane, Samuel, Bernardo, Ganeko, Lopitz-Otsoa, Fernando, Fernández-Ramos, David, Bilbao, Jon, Iglesias, Cristina, Novoa, Eva, Ameneiro, Cristina, Senra, Ana, Beiroa, Daniel, Cuñarro, Juan, Dp Chantada-Vazquez, Maria, Garcia-Vence, Maria, Bravo, Susana B, Da Silva Lima, Natalia, Porteiro, Begoña, Carneiro, Carmen, Vidal, Anxo, Tovar, Sulay, Müller, Timo D, Ferno, Johan, Guallar, Diana, Fidalgo, Miguel, Sabio, Guadalupe, Herzig, Stephan, Yang, Won Ho, Cho, Jin Won, Martinez-Chantar, Maria Luz, Perez-Fernandez, Roman, López, Miguel, Dieguez, Carlos, Mato, Jose M, Millet, Oscar, Coppari, Roberto, Woodhoo, Ashwin, Fruhbeck, Gema, Nogueiras, Ruben
Published in Nature communications (20.08.2021)
Published in Nature communications (20.08.2021)
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The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury
Barbier-Torres, Lucía, Iruzubieta, Paula, Fernández-Ramos, David, Delgado, Teresa C, Taibo, Daniel, Guitiérrez-de-Juan, Virginia, Varela-Rey, Marta, Azkargorta, Mikel, Navasa, Nicolas, Fernández-Tussy, Pablo, Zubiete-Franco, Imanol, Simon, Jorge, Lopitz-Otsoa, Fernando, Lachiondo-Ortega, Sofia, Crespo, Javier, Masson, Steven, McCain, Misti Vanette, Villa, Erica, Reeves, Helen, Elortza, Felix, Lucena, Maria Isabel, Hernández-Alvarez, Maria Isabel, Zorzano, Antonio, Andrade, Raúl J, Lu, Shelly C, Mato, José M, Anguita, Juan, Rincón, Mercedes, Martínez-Chantar, María Luz
Published in Nature communications (12.12.2017)
Published in Nature communications (12.12.2017)
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Metabolic Landscape of the Mouse Liver by Quantitative 31P Nuclear Magnetic Resonance Analysis of the Phosphorome
Bernardo‐Seisdedos, Ganeko, Bilbao, Jon, Fernández‐Ramos, David, Lopitz‐Otsoa, Fernando, Gutierrez de Juan, Virginia, Bizkarguenaga, Maider, Mateos, Borja, Fondevila, Marcos F., Abril‐Fornaguera, Jordi, Diercks, Tammo, Lu, Shelly C., Nogueiras, Rubén, Mato, José M., Millet, Oscar
Published in Hepatology (Baltimore, Md.) (01.07.2021)
Published in Hepatology (Baltimore, Md.) (01.07.2021)
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Aramchol downregulates stearoyl CoA-desaturase 1 in hepatic stellate cells to attenuate cellular fibrogenesis
Bhattacharya, Dipankar, Basta, Brittany, Mato, Jose M., Craig, Amanda, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Tsvirkun, Darya, Hayardeny, Liat, Chandar, Vasuretha, Schwartz, Robert E., Villanueva, Augusto, Friedman, Scott L.
Published in JHEP reports (01.06.2021)
Published in JHEP reports (01.06.2021)
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Therapeutic Targeting of Fumaryl Acetoacetate Hydrolase in Hereditary Tyrosinemia Type I
Gil-Martínez, Jon, Macias, Iratxe, Unione, Luca, Bernardo-Seisdedos, Ganeko, Lopitz-Otsoa, Fernando, Fernandez-Ramos, David, Lain, Ana, Sanz-Parra, Arantza, Mato, José M, Millet, Oscar
Published in International journal of molecular sciences (11.02.2021)
Published in International journal of molecular sciences (11.02.2021)
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SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
Lachiondo-Ortega, Sofia, Rejano-Gordillo, Claudia M., Simon, Jorge, Lopitz-Otsoa, Fernando, C. Delgado, Teresa, Mazan-Mamczarz, Krystyna, Goikoetxea-Usandizaga, Naroa, Zapata-Pavas, L. Estefanía, García-del Río, Ana, Guerra, Pietro, Peña-Sanfélix, Patricia, Hermán-Sánchez, Natalia, Al-Abdulla, Ruba, Fernandez-Rodríguez, Carmen, Azkargorta, Mikel, Velázquez-Cruz, Alejandro, Guyon, Joris, Martín, César, Zalamea, Juan Diego, Egia-Mendikute, Leire, Sanz-Parra, Arantza, Serrano-Maciá, Marina, González-Recio, Irene, Gonzalez-Lopez, Monika, Martínez-Cruz, Luis Alfonso, Pontisso, Patrizia, Aransay, Ana M., Barrio, Rosa, Sutherland, James D., Abrescia, Nicola G.A., Elortza, Félix, Lujambio, Amaia, Banales, Jesus M., Luque, Raúl M., Gahete, Manuel D., Palazón, Asís, Avila, Matias A., G. Marin, Jose J., De, Supriyo, Daubon, Thomas, Díaz-Quintana, Antonio, Díaz-Moreno, Irene, Gorospe, Myriam, Rodríguez, Manuel S., Martínez-Chantar, María Luz
Published in Cell reports (Cambridge) (26.03.2024)
Published in Cell reports (Cambridge) (26.03.2024)
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MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis
Fernández-Ramos, David, Fernández-Tussy, Pablo, Lopitz-Otsoa, Fernando, Gutiérrez-de-Juan, Virginia, Navasa, Nicolás, Barbier-Torres, Lucía, Zubiete-Franco, Imanol, Simón, Jorge, Fernández, Agustín F, Arbelaiz, Ander, Aransay, Ana M, Lavín, José Luis, Beraza, Naiara, Perugorria, María J, Banales, Jesus M, Villa, Erica, Fraga, Mario F, Anguita, Juan, Avila, Matias A, Berasain, Carmen, Iruzibieta, Paula, Crespo, Javier, Lu, Shelly C, Varela-Rey, Marta, Mato, José M, Delgado, Teresa C, Martínez-Chantar, María L
Published in Cell death & disease (20.09.2018)
Published in Cell death & disease (20.09.2018)
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Heterologous SUMO-2/3-ubiquitin chains optimize IκBα degradation and NF-κB activity
Aillet, Fabienne, Lopitz-Otsoa, Fernando, Egaña, Isabel, Hjerpe, Roland, Fraser, Paul, Hay, Ron T, Rodriguez, Manuel S, Lang, Valérie
Published in PloS one (20.12.2012)
Published in PloS one (20.12.2012)
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Scavenger receptors mediate the role of SUMO and Ftz-f1 in Drosophila steroidogenesis
Talamillo, Ana, Herboso, Leire, Pirone, Lucia, Pérez, Coralia, González, Monika, Sánchez, Jonatan, Mayor, Ugo, Lopitz-Otsoa, Fernando, Rodriguez, Manuel S, Sutherland, James D, Barrio, Rosa
Published in PLoS genetics (01.04.2013)
Published in PLoS genetics (01.04.2013)
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A morphological method for ammonia detection in liver
Gutiérrez-de-Juan, Virginia, López de Davalillo, Sergio, Fernández-Ramos, David, Barbier-Torres, Lucía, Zubiete-Franco, Imanol, Fernández-Tussy, Pablo, Simon, Jorge, Lopitz-Otsoa, Fernando, de Las Heras, Javier, Iruzubieta, Paula, Arias-Loste, María Teresa, Villa, Erica, Crespo, Javier, Andrade, Raúl, Lucena, M Isabel, Varela-Rey, Marta, Lu, Shelly C, Mato, José M, Delgado, Teresa Cardoso, Martínez-Chantar, María-Luz
Published in PloS one (20.03.2017)
Published in PloS one (20.03.2017)
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Anti-miR-518d-5p overcomes liver tumor cell death resistance through mitochondrial activity
Fernández-Tussy, Pablo, Rodríguez-Agudo, Rubén, Fernández-Ramos, David, Barbier-Torres, Lucía, Zubiete-Franco, Imanol, Davalillo, Sergio López de, Herraez, Elisa, Goikoetxea-Usandizaga, Naroa, Lachiondo-Ortega, Sofia, Simón, Jorge, Lopitz-Otsoa, Fernando, Juan, Virginia Gutiérrez-de, McCain, Misti V, Perugorria, Maria J, Mabe, Jon, Navasa, Nicolás, Rodrigues, Cecilia M P, Fabregat, Isabel, Boix, Loreto, Sapena, Victor, Anguita, Juan, Lu, Shelly C, Mato, José M, Banales, Jesus M, Villa, Erica, Reeves, Helen L, Bruix, Jordi, Reig, Maria, Marin, Jose J G, Delgado, Teresa C, Martínez-Chantar, María L
Published in Cell death & disease (28.05.2021)
Published in Cell death & disease (28.05.2021)
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SerpinB3 Differently Up-Regulates Hypoxia Inducible Factors -1α and -2α in Hepatocellular Carcinoma: Mechanisms Revealing Novel Potential Therapeutic Targets
Cannito, Stefania, Foglia, Beatrice, Villano, Gianmarco, Turato, Cristian, Delgado, Teresa C, Morello, Elisabetta, Pin, Fabrizio, Novo, Erica, Napione, Lucia, Quarta, Santina, Ruvoletto, Mariagrazia, Fasolato, Silvano, Zanus, Giacomo, Colombatto, Sebastiano, Lopitz-Otsoa, Fernando, Fernández-Ramos, David, Bussolino, Federico, Sutti, Salvatore, Albano, Emanuele, Martínez-Chantar, Maria Luz, Pontisso, Patrizia, Parola, Maurizio
Published in Cancers (04.12.2019)
Published in Cancers (04.12.2019)
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miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease
Fernández-Tussy, Pablo, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Simón, Jorge, Barbier-Torres, Lucía, Gomez-Santos, Beatriz, Nuñez-Garcia, Maitane, Azkargorta, Mikel, Gutiérrez-de Juan, Virginia, Serrano-Macia, Marina, Rodríguez-Agudo, Rubén, Iruzubieta, Paula, Anguita, Juan, Castro, Rui E., Champagne, Devin, Rincón, Mercedes, Elortza, Felix, Arslanow, Anita, Krawczyk, Marcin, Lammert, Frank, Kirchmeyer, Mélanie, Behrmann, Iris, Crespo, Javier, Lu, Shelly C., Mato, José M., Varela-Rey, Marta, Aspichueta, Patricia, Delgado, Teresa C., Martínez-Chantar, María L.
Published in Molecular metabolism (Germany) (01.11.2019)
Published in Molecular metabolism (Germany) (01.11.2019)
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