Dynamic Nuclear Polarization NMR Spectroscopy: Revealing Multiple Conformations in Lipid-Anchored Peptide Vaccines
Koers, Eline J., López-Deber, Maria Pilar, Weingarth, Markus, Nand, Deepak, Hickman, David T., Mlaki Ndao, Dorin, Reis, Pedro, Granet, Anne, Pfeifer, Andrea, Muhs, Andreas, Baldus, Marc
Published in Angewandte Chemie International Edition (04.10.2013)
Published in Angewandte Chemie International Edition (04.10.2013)
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Journal Article
Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau.P301L mice that model tauopathy
Theunis, Clara, Crespo-Biel, Natalia, Gafner, Valérie, Pihlgren, Maria, López-Deber, María Pilar, Reis, Pedro, Hickman, David T, Adolfsson, Oskar, Chuard, Nathalie, Ndao, Dorin Mlaki, Borghgraef, Peter, Devijver, Herman, Van Leuven, Fred, Pfeifer, Andrea, Muhs, Andreas
Published in PloS one (19.08.2013)
Published in PloS one (19.08.2013)
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Journal Article
Engineering amyloid-like assemblies from unstructured peptides via site-specific lipid conjugation
López Deber, María Pilar, Hickman, David T, Nand, Deepak, Baldus, Marc, Pfeifer, Andrea, Muhs, Andreas
Published in PloS one (01.09.2014)
Published in PloS one (01.09.2014)
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Journal Article
An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome
Belichenko, Pavel V, Madani, Rime, Rey-Bellet, Lorianne, Pihlgren, Maria, Becker, Ann, Plassard, Adeline, Vuillermot, Stephanie, Giriens, Valérie, Nosheny, Rachel L, Kleschevnikov, Alexander M, Valletta, Janice S, Bengtsson, Sara K S, Linke, Gordon R, Maloney, Michael T, Hickman, David T, Reis, Pedro, Granet, Anne, Mlaki, Dorin, Lopez-Deber, Maria Pilar, Do, Long, Singhal, Nishant, Masliah, Eliezer, Pearn, Matthew L, Pfeifer, Andrea, Muhs, Andreas, Mobley, William C
Published in PloS one (29.03.2016)
Published in PloS one (29.03.2016)
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Journal Article
T cell independent antibody responses with class switch and memory using peptides anchored on liposomes
Hjálmsdóttir, Ásdís, Hasler, Fabio, Waeckerle-Men, Ying, Duda, Agathe, López-Deber, María Pilar, Pihlgren, Maria, Vukicevic, Marija, Kündig, Thomas M., Johansen, Pål
Published in npj vaccines (22.06.2024)
Published in npj vaccines (22.06.2024)
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Journal Article
TLR4- and TRIF-dependent stimulation of B lymphocytes by peptide liposomes enables T cell–independent isotype switch in mice
Pihlgren, Maria, Silva, Alberto B., Madani, Rime, Giriens, Valérie, Waeckerle-Men, Ying, Fettelschoss, Antonia, Hickman, David T., López-Deber, María Pilar, Ndao, Dorin Mlaki, Vukicevic, Marija, Buccarello, Anna Lucia, Gafner, Valérie, Chuard, Nathalie, Reis, Pedro, Piorkowska, Kasia, Pfeifer, Andrea, Kündig, Thomas M., Muhs, Andreas, Johansen, Pål
Published in Blood (03.01.2013)
Published in Blood (03.01.2013)
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Journal Article
Sequence-independent Control of Peptide Conformation in Liposomal Vaccines for Targeting Protein Misfolding Diseases
Hickman, David T., López-Deber, María Pilar, Ndao, Dorin Mlaki, Silva, Alberto B., Nand, Deepak, Pihlgren, Maria, Giriens, Valérie, Madani, Rime, St-Pierre, Annie, Karastaneva, Hristina, Nagel-Steger, Luitgard, Willbold, Dieter, Riesner, Detlev, Nicolau, Claude, Baldus, Marc, Pfeifer, Andrea, Muhs, Andreas
Published in The Journal of biological chemistry (22.04.2011)
Published in The Journal of biological chemistry (22.04.2011)
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Journal Article
Optimized ACI‐24, an amyloid beta (Abeta) vaccine that safely drives immunity to oligomers and Pyroglutamate Abeta, key pathological species of Alzheimer’s disease (AD)
Fiorini, Emma, Vukicevic, Marija, Carpintero, Rakel, Rincon, Marcela, Lopez‐Deber, Pilar, Piot, Nicolas, Ayer, Maxime, Rentero, Inmaculada, Siegert, Stefanie, Babolin, Chiara, Knittel, Delphine, Gollwitzer, Eva, Bravo‐Veyrat, Sophie, Giriens, Valérie, Morici, Catherine, Beuzelin, Marie‐Gabrielle, Gesbert, Anthony, Rivot, Sebastien, Chuard, Nathalie, Attanasio, Vanessa, Delpretti, Saskia, Donati, Piergiorgio, Streffer, Johannes, Pfeifer, Andrea, Kosco‐Vilbois, Marie
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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Journal Article
Discovery and Structure Activity Relationship of Small Molecule Inhibitors of Toxic β-Amyloid-42 Fibril Formation
Kroth, Heiko, Ansaloni, Annalisa, Varisco, Yvan, Jan, Asad, Sreenivasachary, Nampally, Rezaei-Ghaleh, Nasrollah, Giriens, Valérie, Lohmann, Sophie, López-Deber, María Pilar, Adolfsson, Oskar, Pihlgren, Maria, Paganetti, Paolo, Froestl, Wolfgang, Nagel-Steger, Luitgard, Willbold, Dieter, Schrader, Thomas, Zweckstetter, Markus, Pfeifer, Andrea, Lashuel, Hilal A., Muhs, Andreas
Published in The Journal of biological chemistry (05.10.2012)
Published in The Journal of biological chemistry (05.10.2012)
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Journal Article
NMR-Spektroskopie in Kombination mit dynamischer Kernpolarisation enthüllt mehrere Konformationen in Lipid-verankerten Peptid-Impfstoffen
Koers, Eline J., López-Deber, Maria Pilar, Weingarth, Markus, Nand, Deepak, Hickman, David T., Mlaki Ndao, Dorin, Reis, Pedro, Granet, Anne, Pfeifer, Andrea, Muhs, Andreas, Baldus, Marc
Published in Angewandte Chemie (04.10.2013)
Published in Angewandte Chemie (04.10.2013)
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Journal Article
Immunization with liposome-anchored pegylated peptides modulates doxorubicin sensitivity in P-glycoprotein-expressing P388 cells
Gatouillat, Grégory, Odot, Johann, Balasse, Emilie, Nicolau, Claude, Tosi, Pierre-François, Hickman, David T, López-Deber, María Pilar, Madoulet, Claudie
Published in Cancer letters (18.11.2007)
Published in Cancer letters (18.11.2007)
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Journal Article
An Anti-[beta]-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome
Belichenko, Pavel V, Madani, Rime, Rey-Bellet, Lorianne, Pihlgren, Maria, Becker, Ann, Plassard, Adeline, Vuillermot, Stephanie, Giriens, Valérie, Nosheny, Rachel L, Kleschevnikov, Alexander M, Valletta, Janice S, Bengtsson, Sara K. S, Linke, Gordon R, Maloney, Michael T, Hickman, David T, Reis, Pedro, Granet, Anne, Mlaki, Dorin, Lopez-Deber, Maria Pilar, Do, Long, Singhal, Nishant, Masliah, Eliezer, Pearn, Matthew L, Pfeifer, Andrea, Muhs, Andreas, Mobley, William C
Published in PloS one (29.03.2016)
Published in PloS one (29.03.2016)
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Journal Article
Synthesis of ω-(Hetero)arylalkynylated α-Amino Acid by Sonogashira-type Reactions in Aqueous Media
Brea, Roberto J., Lopez-Deber, M. Pilar, Castedo, Luis, Granja, Juan R.
Published in ChemInform (06.02.2007)
Published in ChemInform (06.02.2007)
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Journal Article
O2–06–04: A liposomal anti‐phospho‐tau vaccine demonstrates higher immunogenicity and specificity than a classical peptide vaccine approach
Gafner, Valerie, Pihlgren, Maria, Lopez Deber, Maria Pilar, Hickman, David T., Reis, Pedro, Craige, Simon, Madani, Rime, Capotosti, Francesca, Adolfsson, Oskar, Chuard, Nathalie, Ndao, Dorin Mlaki, Granet, Anne, Theunis, Clara, Crespo‐Biel, Natalia, Borghgraef, Peter, Devijver, Herman, Pfeifer, Andrea, Van Leuven, Fred, Muhs, Andreas
Published in Alzheimer's & dementia (01.07.2013)
Published in Alzheimer's & dementia (01.07.2013)
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Journal Article
A liposomal anti-phospho-tau vaccine demonstrates higher immunogenicity and specificity than a classical peptide vaccine approach
Gafner, Valerie, Pihlgren, Maria, Lopez Deber, Maria Pilar, Hickman, David T, Reis, Pedro, Craige, Simon, Madani, Rime, Capotosti, Francesca, Adolfsson, Oskar, Chuard, Nathalie, Ndao, Dorin Mlaki, Granet, Anne, Theunis, Clara, Crespo-Biel, Natalia, Borghgraef, Peter, Devijver, Herman, Pfeifer, Andrea, Van Leuven, Fred, Muhs, Andreas
Published in Alzheimer's & dementia (01.07.2013)
Published in Alzheimer's & dementia (01.07.2013)
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Journal Article
P2‐525: Novel phospho‐Tau specific monoclonal antibodies for the treatment of Tau‐mediated pathology
Adolfsson, Oskar, Crespo‐Biel, Natalia, Pihlgren, Maria, Theunis, Clara, Gafner, Valerie, Borghgraef, Peter, Lopez Deber, Maria Pilar, Devijver, Herman, Hickman, David T., Buccarello, Anna Lucia, Chuard, Nathalie
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
P2‐387: Phospho‐tau–specific vaccine for the treatment of tau pathology
Adolfsson, Oskar, Gafner, Valerie, Theunis, Clara, Pihlgren, Maria, Crespo‐Biel, Natalia, Papin, Stephanie, Lopez Deber, Maria Pilar, Borghgraef, Peter, Piorkowska, Kasia, Devijver, Herman, Hickman, David T., Chuard, Nathalie, Reis, Pedro, Antoniello, Katia, Buccarello, Anna Lucia, Paganetti, Paolo, Pfeifer, Andrea, Van Leuven, Fred, Muhs, Andreas
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
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Journal Article
Phospho-tau–specific vaccine for the treatment of tau pathology
Adolfsson, Oskar, Gafner, Valerie, Theunis, Clara, Pihlgren, Maria, Crespo-Biel, Natalia, Papin, Stephanie, Lopez Deber, Maria Pilar, Borghgraef, Peter, Piorkowska, Kasia, Devijver, Herman, Hickman, David T, Chuard, Nathalie, Reis, Pedro, Antoniello, Katia, Buccarello, Anna Lucia, Paganetti, Paolo, Pfeifer, Andrea, Van Leuven, Fred, Muhs, Andreas
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
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Journal Article
O4‐03‐04: Novel phospho‐tau‐specific liposome‐based vaccines to treat tau pathology
Theunis, Clara, Crespo‐Biel, Natalia, Pihlgren, Maria, Borghgraef, Peter, Devijver, Herman, Gafner, Valerie, Hickman, David, Chuard, Nathalie, Lopez Deber, Maria Pilar, Reis, Pedro, Buccarello, Anna Lucia, Adolfsson, Oskar, Roeber, Sigrun, Kretzschmar, Hans, Pfeifer, Andrea, Muhs, Andreas, Van Leuven, Fred
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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