Radiological Patterns of Drug-induced Interstitial Lung Disease (DILD) in Early-phase Oncology Clinical Trials
Terbuch, Angelika, Tiu, Crescens, Candilejo, Irene Moreno, Scaranti, Mariana, Curcean, Andra, Bar, Dan, Estevez Timon, Miriam, Ameratunga, Malaka, Ang, Joo Ern, Ratoff, Jonathan, Minchom, Anna R, Banerji, Udai, de Bono, Johann S, Tunariu, Nina, Lopez, Juanita S
Published in Clinical cancer research (15.09.2020)
Published in Clinical cancer research (15.09.2020)
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Journal Article
A Wolf in Sheep's Clothing: Systemic Immune Activation Post Immunotherapy
Tiu, Crescens, Shinde, Rajiv, Pal, Abhijit, Biondo, Andrea, Lee, Alex, Tunariu, Nina, Jhanji, Shaman, Grover, Vimal, Tatham, Kate, Gruber, Pascale, Banerji, Udai, De Bono, Johann S, Nicholson, Emma, Minchom, Anna R, Lopez, Juanita S
Published in Journal of Immunotherapy and Precision Oncology (01.11.2021)
Published in Journal of Immunotherapy and Precision Oncology (01.11.2021)
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Journal Article
To Cycle or Fight-CDK4/6 Inhibitors at the Crossroads of Anticancer Immunity
Ameratunga, Malaka, Kipps, Emma, Okines, Alicia F C, Lopez, Juanita S
Published in Clinical cancer research (01.01.2019)
Published in Clinical cancer research (01.01.2019)
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Journal Article
Phase I Trial of the PARP Inhibitor Olaparib and AKT Inhibitor Capivasertib in Patients with BRCA1/2 - and Non- BRCA1/2 -Mutant Cancers
Yap, Timothy A, Kristeleit, Rebecca, Michalarea, Vasiliki, Pettitt, Stephen J, Lim, Joline S J, Carreira, Suzanne, Roda, Desamparados, Miller, Rowan, Riisnaes, Ruth, Miranda, Susana, Figueiredo, Ines, Rodrigues, Daniel Nava, Ward, Sarah, Matthews, Ruth, Parmar, Mona, Turner, Alison, Tunariu, Nina, Chopra, Neha, Gevensleben, Heidrun, Turner, Nicholas C, Ruddle, Ruth, Raynaud, Florence I, Decordova, Shaun, Swales, Karen E, Finneran, Laura, Hall, Emma, Rugman, Paul, Lindemann, Justin P O, Foxley, Andrew, Lord, Christopher J, Banerji, Udai, Plummer, Ruth, Basu, Bristi, Lopez, Juanita S, Drew, Yvette, de Bono, Johann S
Published in Cancer discovery (01.10.2020)
Published in Cancer discovery (01.10.2020)
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Journal Article
Triplet Therapy with Palbociclib, Taselisib, and Fulvestrant in PIK3CA -Mutant Breast Cancer and Doublet Palbociclib and Taselisib in Pathway-Mutant Solid Cancers
Pascual, Javier, Lim, Joline S J, Macpherson, Iain R, Armstrong, Anne C, Ring, Alistair, Okines, Alicia F C, Cutts, Rosalind J, Herrera-Abreu, Maria Teresa, Garcia-Murillas, Isaac, Pearson, Alex, Hrebien, Sarah, Gevensleben, Heidrun, Proszek, Paula Z, Hubank, Michael, Hills, Margaret, King, Jenny, Parmar, Mona, Prout, Toby, Finneran, Laura, Malia, Jason, Swales, Karen E, Ruddle, Ruth, Raynaud, Florence I, Turner, Alison, Hall, Emma, Yap, Timothy A, Lopez, Juanita S, Turner, Nicholas C
Published in Cancer discovery (01.01.2021)
Published in Cancer discovery (01.01.2021)
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Journal Article
A risk-based approach to experimental early phase clinical trials during the COVID-19 pandemic
Tiu, Crescens, Shinde, Rajiv, Yap, Christina, Rao Baikady, Bindumalini, Banerji, Udai, Minchom, Anna R, de Bono, Johann S, Lopez, Juanita S
Published in The lancet oncology (01.07.2020)
Published in The lancet oncology (01.07.2020)
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Journal Article
Adult brain tumour research in 2024: Status, challenges and recommendations
Purshouse, Karin, Bulbeck, Helen J., Rooney, Alasdair G., Noble, Karen E., Carruthers, Ross D., Thompson, Gerard, Hamerlik, Petra, Yap, Christina, Kurian, Kathreena M., Jefferies, Sarah J., Lopez, Juanita S., Jenkinson, Michael D., Hanemann, C. Oliver, Stead, Lucy F.
Published in Neuropathology and applied neurobiology (01.04.2024)
Published in Neuropathology and applied neurobiology (01.04.2024)
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Journal Article
The role of genomic profiling in adolescents and young adults (AYAs) with advanced cancer participating in phase I clinical trials
McVeigh, Terri Patricia, Sundar, Raghav, Diamantis, Nikolaos, Kaye, Stan B., Banerji, Udai, Lopez, Juanita S., de Bono, Johann, van der Graaf, Winette T.A., George, Angela J.
Published in European journal of cancer (1990) (01.05.2018)
Published in European journal of cancer (1990) (01.05.2018)
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Journal Article
Abstract CT010: Phase I trial combining the PARP inhibitor olaparib (Ola) and AKT inhibitor AZD5363 (AZD) in germline (g)BRCA and non-BRCA mutant (m) advanced cancer patients (pts) incorporating noninvasive monitoring of cancer mutations
Michalarea, Vasiliki, Roda, Desam, Drew, Yvette, Carreira, Suzanne, O’Carrigan, Brent S., Shaw, Heather, Roux, Rene, Kumar, Sanjeev, Ward, Sarah, Parmar, Mona, Turner, Alison, Hall, Emma, Serrano Fandos, Sonia, Perez, Raquel, Tunariu, Nina, Raynaud, Florence, Cullberg, Marie, Foxley, Andrew, Lindemann, Justin PO, Pass, Martin, Rugman, Paul, Lopez, Juanita S., Banerji, Udai, Basu, Bristi, Plummer, Ruth, Kristeleit, Rebecca, de Bono, Johann S., Yap, Timothy A.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract CT120: Results of the glioblastoma multiforme (GBM) cohort of phase 1 trial Ice-CAP (NCT03673787): Preliminary evidence of antitumour activity of Ipatasertib (Ipa) and Atezolizumab (A) in patients (pts) with PTEN loss
Tiu, Crescens, Biondo, Andrea, Welsh, Liam C., Jones, Timothy L., Zachariou, Anna, Prout, Toby, Turner, Alison J., Daly, Robert, Vivanco, Igor, Yap, Christina, Jenkins, Ben, Crespo, Mateus, Riisnaes, Ruth, Carreira, Suzanne, Gurel, Bora, Tunariu, Nina, Minchom, Anna, Banerji, Udai, de Bono, Johann S., Lopez, Juanita S.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract CT140: Proof-of-concept evidence of immune modulation by blockade of the phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway in the phase I dose escalation study of Ipatasertib (Ipa) in combination with atezolizumab (A) in patients (pts) with advanced solid tumors (Ice-CAP)
Lopez, Juanita S., Biondo, Andrea, Tiu, Crescens, Scaranti, Mariana, Ameratunga, Malaka, Zachariou, Anna, Turner, Alison, Tunariu, Nina, Prout, Toby, Parmar, Mona, Badham, Hannah, Swales, Karen, Yuan, Wei, Morilla, Ricardo, Crespo, Mateus, Daly, Rob, Figueiredo, Ines, Gurel, Bora, Pereira, Rita, Riisnaes, Ruth, Vivanco, Igor, Minchom, Anna, Jenkins, Ben, Yap, Christina, Banerji, Udai, De Bono, Johann
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Update on Clinical Safety and Efficacy of the Novel Oral Dual RAF/MEK Inhibitor RO5126766 (CH5127566) in RAS-mutant Multiple Myeloma
Sriskandarajah, Priya, Boyd, Kevin, Xu, Wen, Moreno Candilejo, Irene, Ellis, Sidra, Price, Amy, Sherborne, Amy L, Croft, James, Shah, Vallari, Dawes, Joanna, Parmar, Mona, Turner, Alison, Hall, Emma, Tunariu, Nina, Lopez, Juanita S, de Bono, Johann S., Banerji, Udai, Kaiser, Martin
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
Abstract CT301: A phase Ib study to evaluate RO7198457, an individualized Neoantigen Specific immunoTherapy (iNeST), in combination with atezolizumab in patients with locally advanced or metastatic solid tumors
Lopez, Juanita S., Camidge, Ross, Iafolla, Marco, Rottey, Sylvie, Schuler, Martin, Hellmann, Matthew, Balmanoukian, Ani, Dirix, Luc, Gordon, Michael, Sullivan, Ryan, Henick, Brian S., Drake, Charles, Wong, Kit, LoRusso, Patricia, Ott, Patrick, Fong, Lawrence, Schiza, Aglaia, Yachnin, Jeffery, Ottensmeier, Christian, Braiteh, Fadi, Bendell, Johanna, Leidner, Rom, Fisher, George, Jerusalem, Guy, Molenaar-Kuijsten, Laura, Schmidt, Marcus, Laurie, Scott A., Aljumaily, Raid, Rittmeyer, Achim, Gort, Eelke, Melero, Ignacio, Mueller, Lars, Sabado, Rachel, Twomey, Patrick, Huang, Jack, Yadav, Manesh, Zhang, Jingbin, Mueller, Felicitas, Derhovanessian, Evelyna, Sahin, Ugur, Türeci, Özlem, Powles, Thomas
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract CT276: Preliminary analysis of pharmacokinetic (PK) and target engagement biomarkers from a first in human phase 1 study of immunomodulatory aryl hydrocarbon receptor (AhR) inhibitor BAY2416964
Papadopoulos, Kyriakos, Cecchini, Michael, Lopez, Juanita S., Jäger, Dirk, Chung, Ki Young, Platten, Michael, Prinz, Florian, Ishii, Yuko, Schaer, David, Gutcher, Ilona, Leder, Gabriele, Pencheva, Radost, Wagener, Thomas, Scheerans, Christian, Zieschang, Carsten, Wagner, Andrea, Stamatelos, Spyros, Dumbrava, Ecaterina
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Abstract CT253: Phase 1/2 study of the safety, pharmacokinetics, and preliminary clinical activity of BT7480 in patients with nectin-4 associated advanced malignancies
Evans, Thomas R., Dowlati, Afshin, Lopez, Juanita S., Milhem, Mohammed M., Ahnert, Jordi Rodón, Spira, Alexander, Carvajal, Richard D., Zibelman, Matthew, Hazard, Sebastien J., Dickson, Amy, Xu, Lei, Cohen, Heather, Bader, Justin, Hurov, Kristen, Sharma, Rajiv, Smethurst, Dominic, Papadopoulos, Kyriakos P.
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Journal Article
Abstract CT067: 2-hydroxyoleic acid (2-OHOA), a novel activator of sphingomyelin synthase with antitumor activity in refractory glioblastoma: results of the first-in-human dose-escalation (DE) study in patients with advanced solid tumors (AST) and refractory gliomasglioblastomas
Lopez, Juanita S, Fontes, Mariane, Coleman, Niamh, Azaro, Analia, Drew, Yvette, Escriba, Pablo, Busquets, Xavier, Veal, Gareth, Tur, Vicenc, Perier, Antoine, Sicart, Elisabet, Molife, Rhoda, Plummer, Ruth, Rodon, Jordi
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract CT067: 2-hydroxyoleic acid (2-OHOA), a novel activator of sphingomyelin synthase with antitumor activity in refractory glioblastoma: results of the first-in-human dose-escalation (DE) study in patients with advanced solid tumors (AST) and refractory gliomas/glioblastomas
Lopez, Juanita S., Fontes, Mariane, Coleman, Niamh, Azaro, Analia, Drew, Yvette, Escriba, Pablo, Busquets, Xavier, Veal, Gareth, Tur, Vicenc, Perier, Antoine, Sicart, Elisabet, Molife, Rhoda, Plummer, Ruth, Rodon, Jordi
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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