Direct Comparison of [18F]F-DPA with [18F]DPA-714 and [11C]PBR28 for Neuroinflammation Imaging in the same Alzheimer’s Disease Model Mice and Healthy Controls
López-Picón, Francisco R., Keller, Thomas, Bocancea, Diana, Helin, Jatta S., Krzyczmonik, Anna, Helin, Semi, Damont, Annelaure, Dollé, Frédéric, Rinne, Juha O., Haaparanta-Solin, Merja, Solin, Olof
Published in Molecular imaging and biology (01.02.2022)
Published in Molecular imaging and biology (01.02.2022)
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Radiosynthesis and Preclinical Evaluation of [18F]F-DPA, A Novel Pyrazolo[1,5a]pyrimidine Acetamide TSPO Radioligand, in Healthy Sprague Dawley Rats
Keller, Thomas, Krzyczmonik, Anna, Forsback, Sarita, Picón, Francisco R. López, Kirjavainen, Anna K., Takkinen, Jatta, Rajander, Johan, Cacheux, Fanny, Damont, Annelaure, Dollé, Frédéric, Rinne, Juha O., Haaparanta-Solin, Merja, Solin, Olof
Published in Molecular imaging and biology (01.10.2017)
Published in Molecular imaging and biology (01.10.2017)
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Journal Article
ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer's disease with a bispecific, brain-penetrating fusion protein
Bonvicini, Gillian, Syvänen, Stina, Andersson, Ken G, Haaparanta-Solin, Merja, López-Picón, Francisco, Sehlin, Dag
Published in Translational neurodegeneration (26.12.2022)
Published in Translational neurodegeneration (26.12.2022)
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Journal Article
Biomarkers of the Endocannabinoid System in Substance Use Disorders
Navarrete, Francisco, García-Gutiérrez, María S, Gasparyan, Ani, Navarro, Daniela, López-Picón, Francisco, Morcuende, Álvaro, Femenía, Teresa, Manzanares, Jorge
Published in Biomolecules (Basel, Switzerland) (03.03.2022)
Published in Biomolecules (Basel, Switzerland) (03.03.2022)
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Journal Article
Ruthenium-Mediated 18F‑Fluorination and Preclinical Evaluation of a New CB1 Receptor Imaging Agent [18F]FPATPP
Lahdenpohja, Salla, Rajala, Noora A, Helin, Jatta S, Haaparanta-Solin, Merja, Solin, Olof, López-Picón, Francisco R, Kirjavainen, Anna K
Published in ACS chemical neuroscience (01.07.2020)
Published in ACS chemical neuroscience (01.07.2020)
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Journal Article
Segmentation of Dynamic Total-Body [18F]-FDG PET Images Using Unsupervised Clustering
Jaakkola, Maria K., Rantala, Maria, Jalo, Anna, Saari, Teemu, Hentilä, Jaakko, Helin, Jatta S., Nissinen, Tuuli A., Eskola, Olli, Rajander, Johan, Virtanen, Kirsi A., Hannukainen, Jarna C., López-Picón, Francisco, Klén, Riku
Published in International journal of biomedical imaging (2023)
Published in International journal of biomedical imaging (2023)
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Journal Article
Application of advanced brain positron emission tomography–based molecular imaging for a biological framework in neurodegenerative proteinopathies
Perani, Daniela, Iaccarino, Leonardo, Jacobs, Andreas H., Lammertsma, Adriaan A., Nordberg, Agneta, Windhorst, Albert D., Gerhard, Alexander, Winkeler, Alexandra, Jacobs, Andreas H., Gee, Anthony, Kuhnast, Bertrand, Halldin, Christer, Perani, Daniela, Brooks, David, Rodriguez-Vieitez, Elena, Turkheimer, Federico E., López-Picón, Francisco, Knudsen, Gitte M., Vercouillie, Johnny, Rinne, Juha O., Herholz, Karl, Van Laere, Koen, Varrone, Andrea, Santiago-Ribeiro, Marie Joao, Herth, Matthias M., Carroll, Michael A., Chalon, Sylvie, Bottlaender, Michel, Hansson, Oskar, Edison, Paul, Hinz, Rainer, Boellaard, Ronald, Moresco, Rosa Maria, Pappata, Sabina
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (01.12.2019)
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (01.12.2019)
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Journal Article
18 F-labeled norepinephrine transporter tracer [ 18 F]NS12137: radiosynthesis and preclinical evaluation
Kirjavainen, Anna K, Forsback, Sarita, López-Picón, Francisco R, Marjamäki, Päivi, Takkinen, Jatta, Haaparanta-Solin, Merja, Peters, Dan, Solin, Olof
Published in Nuclear medicine and biology (01.01.2018)
Published in Nuclear medicine and biology (01.01.2018)
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Journal Article
Neuroinflammation Appears Early on PET Imaging and Then Plateaus in a Mouse Model of Alzheimer Disease
López-Picón, Francisco R, Snellman, Anniina, Eskola, Olli, Helin, Semi, Solin, Olof, Haaparanta-Solin, Merja, Rinne, Juha O
Published in Journal of Nuclear Medicine (01.03.2018)
Published in Journal of Nuclear Medicine (01.03.2018)
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Journal Article
[ 18 F]FMPEP-d 2 PET imaging shows age- and genotype-dependent impairments in the availability of cannabinoid receptor 1 in a mouse model of Alzheimer's disease
Takkinen, Jatta S, López-Picón, Francisco R, Kirjavainen, Anna K, Pihlaja, Rea, Snellman, Anniina, Ishizu, Tamiko, Löyttyniemi, Eliisa, Solin, Olof, Rinne, Juha O, Haaparanta-Solin, Merja
Published in Neurobiology of aging (01.09.2018)
Published in Neurobiology of aging (01.09.2018)
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Journal Article
(S)-[18F]THK5117 brain uptake is associated with Aβ plaques and MAO-B enzyme in a mouse model of Alzheimer's disease
Alzghool, Obada M., Rokka, Johanna, López-Picón, Francisco R., Snellman, Anniina, Helin, Jatta S., Okamura, Nobuyuki, Solin, Olof, Rinne, Juha O., Haaparanta-Solin, Merja
Published in Neuropharmacology (15.09.2021)
Published in Neuropharmacology (15.09.2021)
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Journal Article
Prodromal neuroinflammatory, cholinergic and metabolite dysfunction detected by PET and MRS in the TgF344-AD transgenic rat model of AD: a collaborative multi-modal study
Chaney, Aisling M, Lopez-Picon, Francisco R, Serrière, Sophie, Wang, Rui, Bochicchio, Daniela, Webb, Samuel D, Vandesquille, Matthias, Harte, Michael K, Georgiadou, Christina, Lawrence, Catherine, Busson, Julie, Vercouillie, Johnny, Tauber, Clovis, Buron, Frédéric, Routier, Sylvain, Reekie, Tristan, Snellman, Anniina, Kassiou, Michael, Rokka, Johanna, Davies, Karen E, Rinne, Juha O, Salih, Dervis A, Edwards, Frances A, Orton, Llwyd D, Williams, Stephen R, Chalon, Sylvie, Boutin, Hervé
Published in Theranostics (01.01.2021)
Published in Theranostics (01.01.2021)
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Journal Article
Luminometric Nanoparticle-Based Assay for High Sensitivity Detection of β‑Amyloid Aggregation
Pihlasalo, Sari, Deguchi, Takahiro, Virtamo, Maria, Jacobino, Jenna, Chary, Karthik, López-Picón, Francisco R, Brunhofer-Bolzer, Gerda, Huttunen, Roope, Fallarero, Adyary, Vuorela, Pia, Härmä, Harri
Published in Analytical chemistry (Washington) (21.02.2017)
Published in Analytical chemistry (Washington) (21.02.2017)
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Journal Article
Effect of genotype and age on cerebral [ 18 F]FDG uptake varies between transgenic APP Swe -PS1 dE9 and Tg2576 mouse models of Alzheimer's disease
Snellman, Anniina, Takkinen, Jatta S, López-Picón, Francisco R, Eskola, Olli, Solin, Olof, Rinne, Juha O, Haaparanta-Solin, Merja
Published in Scientific reports (01.12.2019)
Published in Scientific reports (01.12.2019)
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Journal Article
Comparison of high and low molar activity TSPO tracer [18F]F-DPA in a mouse model of Alzheimer’s disease
Keller, Thomas, López-Picón, Francisco R, Krzyczmonik, Anna, Forsback, Sarita, Takkinen, Jatta S, Rajander, Johan, Teperi, Simo, Dollé, Frédéric, Rinne, Juha O, Haaparanta-Solin, Merja, Solin, Olof
Published in Journal of cerebral blood flow and metabolism (01.05.2020)
Published in Journal of cerebral blood flow and metabolism (01.05.2020)
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Journal Article
Monoacylglycerol lipase inhibitor JZL184 reduces neuroinflammatory response in APdE9 mice and in adult mouse glial cells
Pihlaja, Rea, Takkinen, Jatta, Eskola, Olli, Vasara, Jenni, López-Picón, Francisco R, Haaparanta-Solin, Merja, Rinne, Juha O
Published in Journal of neuroinflammation (28.04.2015)
Published in Journal of neuroinflammation (28.04.2015)
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Journal Article
Applicability of [11 C]PIB micro-PET imaging for in vivo follow-up of anti-amyloid treatment effects in APP23 mouse model
Snellman, Anniina, Rokka, Johanna, Lopez-Picon, Francisco R, Helin, Semi, Re, Francesca, Löyttyniemi, Eliisa, Pihlaja, Rea, Forloni, Gianluigi, Salmona, Mario, Masserini, Massimo, Solin, Olof, Rinne, Juha O, Haaparanta-Solin, Merja
Published in Neurobiology of aging (01.09.2017)
Published in Neurobiology of aging (01.09.2017)
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Journal Article
Intravenous transplantation of olfactory ensheathing cells reduces neuroinflammation after spinal cord injury via interleukin-1 receptor antagonist
Zhang, Lijian, Zhuang, Xiaoqing, Kotitalo, Päivi, Keller, Thomas, Krzyczmonik, Anna, Haaparanta-Solin, Merja, Solin, Olof, Forsback, Sarita, Grönroos, Tove J, Han, Chunlei, López-Picón, Francisco R, Xia, Hechun
Published in Theranostics (2021)
Published in Theranostics (2021)
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Journal Article
[18F]F-DPA for the detection of activated microglia in a mouse model of Alzheimer's disease
Keller, Thomas, López-Picón, Francisco R., Krzyczmonik, Anna, Forsback, Sarita, Kirjavainen, Anna K., Takkinen, Jatta S., Alzghool, Obada, Rajander, Johan, Teperi, Simo, Cacheux, Fanny, Damont, Annelaure, Dollé, Frédéric, Rinne, Juha O., Solin, Olof, Haaparanta-Solin, Merja
Published in Nuclear medicine and biology (01.12.2018)
Published in Nuclear medicine and biology (01.12.2018)
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