Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis
Boroviak, Thorsten, Loos, Remco, Lombard, Patrick, Okahara, Junko, Behr, Rüdiger, Sasaki, Erika, Nichols, Jennifer, Smith, Austin, Bertone, Paul
Published in Developmental cell (09.11.2015)
Published in Developmental cell (09.11.2015)
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Resetting transcription factor control circuitry toward ground-state pluripotency in human
Takashima, Yasuhiro, Guo, Ge, Loos, Remco, Nichols, Jennifer, Ficz, Gabriella, Krueger, Felix, Oxley, David, Santos, Fatima, Clarke, James, Mansfield, William, Reik, Wolf, Bertone, Paul, Smith, Austin
Published in Cell (11.09.2014)
Published in Cell (11.09.2014)
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The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression
Bornelöv, Susanne, Reynolds, Nicola, Xenophontos, Maria, Gharbi, Sarah, Johnstone, Ewan, Floyd, Robin, Ralser, Meryem, Signolet, Jason, Loos, Remco, Dietmann, Sabine, Bertone, Paul, Hendrich, Brian
Published in Molecular cell (05.07.2018)
Published in Molecular cell (05.07.2018)
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Nuclear Architecture Organized by Rif1 Underpins the Replication-Timing Program
Foti, Rossana, Gnan, Stefano, Cornacchia, Daniela, Dileep, Vishnu, Bulut-Karslioglu, Aydan, Diehl, Sarah, Buness, Andreas, Klein, Felix A., Huber, Wolfgang, Johnstone, Ewan, Loos, Remco, Bertone, Paul, Gilbert, David M., Manke, Thomas, Jenuwein, Thomas, Buonomo, Sara C.B.
Published in Molecular cell (21.01.2016)
Published in Molecular cell (21.01.2016)
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Journal Article
Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human
Takashima, Yasuhiro, Guo, Ge, Loos, Remco, Nichols, Jennifer, Ficz, Gabriella, Krueger, Felix, Oxley, David, Santos, Fatima, Clarke, James, Mansfield, William, Reik, Wolf, Bertone, Paul, Smith, Austin
Published in Cell (16.07.2015)
Published in Cell (16.07.2015)
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Comparison of RNA-seq and microarray platforms for splice event detection using a cross-platform algorithm
Romero, Juan P, Ortiz-Estévez, María, Muniategui, Ander, Carrancio, Soraya, de Miguel, Fernando J, Carazo, Fernando, Montuenga, Luis M, Loos, Remco, Pío, Rubén, Trotter, Matthew W B, Rubio, Angel
Published in BMC genomics (25.09.2018)
Published in BMC genomics (25.09.2018)
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SMG1, a nonsense‐mediated mRNA decay (NMD) regulator, as a candidate therapeutic target in multiple myeloma
Leeksma, Alexander C., Derks, Ingrid A. M., Garrick, Brett, Jongejan, Aldo, Colombo, Martino, Bloedjes, Timon, Trowe, Torsten, Leisten, Jim C., Howarth, Michelle, Malek, Mehnaz, Mortensen, Deborah S., Blease, Kate, Groza, Mathew C., Narla, Rama Krishna, Loos, Remco, Kersten, Marie‐José, Moerland, Perry D., Guikema, Jeroen E. J., Kater, Arnon P., Eldering, Eric, Filvaroff, Ellen H.
Published in Molecular oncology (01.02.2023)
Published in Molecular oncology (01.02.2023)
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In Vitro 3D Spheroid Culture System Displays Sustained T Cell‐dependent CLL Proliferation and Survival
Haselager, Marco V., Driel, Bianca F., Perelaer, Eduard, Rooij, Dennis, Lashgari, Danial, Loos, Remco, Kater, Arnon P., Moerland, Perry D., Eldering, Eric
Published in HemaSphere (01.09.2023)
Published in HemaSphere (01.09.2023)
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Journal Article
Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex
Miller, Anzy, Ralser, Meryem, Kloet, Susan L, Loos, Remco, Nishinakamura, Ryuichi, Bertone, Paul, Vermeulen, Michiel, Hendrich, Brian
Published in Development (Cambridge) (01.09.2016)
Published in Development (Cambridge) (01.09.2016)
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Journal Article
Citrullination regulates pluripotency and histone H1 binding to chromatin
Christophorou, Maria A., Castelo-Branco, Gonçalo, Halley-Stott, Richard P., Oliveira, Clara Slade, Loos, Remco, Radzisheuskaya, Aliaksandra, Mowen, Kerri A., Bertone, Paul, Silva, José C. R., Zernicka-Goetz, Magdalena, Nielsen, Michael L., Gurdon, John B., Kouzarides, Tony
Published in Nature (London) (06.03.2014)
Published in Nature (London) (06.03.2014)
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NuRD Suppresses Pluripotency Gene Expression to Promote Transcriptional Heterogeneity and Lineage Commitment
Reynolds, Nicola, Latos, Paulina, Hynes-Allen, Antony, Loos, Remco, Leaford, Donna, O'Shaughnessy, Aoife, Mosaku, Olukunbi, Signolet, Jason, Brennecke, Philip, Kalkan, Tüzer, Costello, Ita, Humphreys, Peter, Mansfield, William, Nakagawa, Kentaro, Strouboulis, John, Behrens, Axel, Bertone, Paul, Hendrich, Brian
Published in Cell stem cell (04.05.2012)
Published in Cell stem cell (04.05.2012)
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Interactome of Aiolos/Ikaros Reveals Combination Rationale of Cereblon Modulators with HDAC Inhibitors in DLBCL
Hagner, Patrick R, Chiu, Hsiling, Chopra, Vivek S, Colombo, Martino, Patel, Nisha, Estevez, Maria Ortiz, Waldman, Michelle F, Loos, Remco, Towfic, Fadi, Gandhi, Anita K
Published in Clinical cancer research (02.08.2022)
Published in Clinical cancer research (02.08.2022)
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Interactome of Aiolos/Ikaros in Diffuse Large B-Cell Lymphoma (DLBCL) Reveals Novel Combination of Cereblon Modulators (CELMoD) and Histone Deacetylase (HDAC) Inhibitors
Hagner, Patrick R., Chiu, Hsiling, Chopra, Vivek S., Colombo, Martino S., Patel, Nisha, Ortiz, Maria, Loos, Remco S., Towfic, Fadi, Waldman, Michelle, Gandhi, Anita K
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Rap-536 Induces Reticulocyte Maturation in Wild-Type Mice, Increases Survival of Beta-Thalassemic Reticulocytes, and Increases Red Blood Cells in a Mouse Model of Alpha-Thalassemia
Acar, Melih, Jupelli, Madhulika, Abbiati, Roberto A., Ramanathan, Harish N., Santini, Cristina C., Ratushny, Alexander, Dunshee, Diana R., Lopes de Menezes, Daniel, MacBeth, Kyle, Suragani, Rajasekhar N.V.S., Loos, Remco, Schwickart, Martin
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
iNucs: inter-nucleosome interactions
Oveisi, Mehrdad, Shukla, Manu, Seymen, Nogayhan, Ohno, Masae, Taniguchi, Yuichi, Nahata, Sunil, Loos, Remco, Mufti, Ghulam J, Allshire, Robin C, Dimitrov, Stefan, Karimi, Mohammad M
Published in Bioinformatics (01.12.2021)
Published in Bioinformatics (01.12.2021)
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Quantitative Systems Pharmacology Modeling of Avadomide-Induced Neutropenia Enables Virtual Clinical Dose and Schedule Finding Studies
Abbiati, Roberto A., Pourdehnad, Michael, Carrancio, Soraya, Pierce, Daniel W., Kasibhatla, Shailaja, McConnell, Mark, Trotter, Matthew W. B., Loos, Remco, Santini, Cristina C., Ratushny, Alexander V.
Published in The AAPS journal (27.08.2021)
Published in The AAPS journal (27.08.2021)
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