Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy
Wang, Yujue, Liu, Sixue, Yang, Zhentao, Algazi, Alain P., Lomeli, Shirley H., Wang, Yan, Othus, Megan, Hong, Aayoung, Wang, Xiaoyan, Randolph, Chris E., Jones, Alexis M., Bosenberg, Marcus W., Byrum, Stephanie D., Tackett, Alan J., Lopez, Henry, Yates, Clayton, Solit, David B., Ribas, Antoni, Piva, Marco, Moriceau, Gatien, Lo, Roger S.
Published in Cancer cell (11.10.2021)
Published in Cancer cell (11.10.2021)
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Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
Hugo, Willy, Zaretsky, Jesse M., Sun, Lu, Song, Chunying, Moreno, Blanca Homet, Hu-Lieskovan, Siwen, Berent-Maoz, Beata, Pang, Jia, Chmielowski, Bartosz, Cherry, Grace, Seja, Elizabeth, Lomeli, Shirley, Kong, Xiangju, Kelley, Mark C., Sosman, Jeffrey A., Johnson, Douglas B., Ribas, Antoni, Lo, Roger S.
Published in Cell (24.03.2016)
Published in Cell (24.03.2016)
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Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
Hugo, Willy, Zaretsky, Jesse M., Sun, Lu, Song, Chunying, Moreno, Blanca Homet, Hu-Lieskovan, Siwen, Berent-Maoz, Beata, Pang, Jia, Chmielowski, Bartosz, Cherry, Grace, Seja, Elizabeth, Lomeli, Shirley, Kong, Xiangju, Kelley, Mark C., Sosman, Jeffrey A., Johnson, Douglas B., Ribas, Antoni, Lo, Roger S.
Published in Cell (26.01.2017)
Published in Cell (26.01.2017)
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Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH
Hung, King L., Luebeck, Jens, Dehkordi, Siavash R., Colón, Caterina I., Li, Rui, Wong, Ivy Tsz-Lo, Coruh, Ceyda, Dharanipragada, Prashanthi, Lomeli, Shirley H., Weiser, Natasha E., Moriceau, Gatien, Zhang, Xiao, Bailey, Chris, Houlahan, Kathleen E., Yang, Wenting, González, Rocío Chamorro, Swanton, Charles, Curtis, Christina, Jamal-Hanjani, Mariam, Henssen, Anton G., Law, Julie A., Greenleaf, William J., Lo, Roger S., Mischel, Paul S., Bafna, Vineet, Chang, Howard Y.
Published in Nature genetics (01.11.2022)
Published in Nature genetics (01.11.2022)
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Blocking Genomic Instability Prevents Acquired Resistance to MAPK Inhibitor Therapy in Melanoma
Dharanipragada, Prashanthi, Zhang, Xiao, Liu, Sixue, Lomeli, Shirley H, Hong, Aayoung, Wang, Yan, Yang, Zhentao, Lo, Kara Z, Vega-Crespo, Agustin, Ribas, Antoni, Moschos, Stergios J, Moriceau, Gatien, Lo, Roger S
Published in Cancer discovery (03.04.2023)
Published in Cancer discovery (03.04.2023)
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Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance
Yang, Zhentao, Wang, Yan, Liu, Sixue, Deng, Weixian, Lomeli, Shirley H, Moriceau, Gatien, Wohlschlegel, James, Piva, Marco, Lo, Roger S
Published in Cancer discovery (05.08.2022)
Published in Cancer discovery (05.08.2022)
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Multi-organ landscape of therapy-resistant melanoma
Liu, Sixue, Dharanipragada, Prashanthi, Lomeli, Shirley H., Wang, Yan, Zhang, Xiao, Yang, Zhentao, Lim, Raymond J., Dumitras, Camelia, Scumpia, Philip O., Dubinett, Steve M., Moriceau, Gatien, Johnson, Douglas B., Moschos, Stergios J., Lo, Roger S.
Published in Nature medicine (01.05.2023)
Published in Nature medicine (01.05.2023)
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Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity
Hong, Aayoung, Piva, Marco, Liu, Sixue, Hugo, Willy, Lomeli, Shirley H, Zoete, Vincent, Randolph, Christopher E, Yang, Zhentao, Wang, Yan, Lee, Jordan J, Lo, Skylar J, Sun, Lu, Vega-Crespo, Agustin, Garcia, Alejandro J, Shackelford, David B, Dubinett, Steven M, Scumpia, Philip O, Byrum, Stephanie D, Tackett, Alan J, Donahue, Timothy R, Michielin, Olivier, Holmen, Sheri L, Ribas, Antoni, Moriceau, Gatien, Lo, Roger S
Published in Cancer discovery (01.03.2021)
Published in Cancer discovery (01.03.2021)
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A phase 1 study of triple‐targeted therapy with BRAF, MEK, and AKT inhibitors for patients with BRAF‐mutated cancers
Algazi, Alain P., Moon, James, Lao, Christopher D., Chmielowski, Bartosz, Kendra, Kari L., Lewis, Karl D., Gonzalez, Rene, Kim, Kevin, Godwin, John E., Curti, Brendan D., Latkovic‐Taber, Michaella, Lomeli, Shirley H., Gufford, Brandon T., Scumpia, Philip O., Lo, Roger S., Othus, Megan, Ribas, Antoni
Published in Cancer (15.05.2024)
Published in Cancer (15.05.2024)
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Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges
Song, Kai, Minami, Jenna K, Huang, Arthur, Dehkordi, Siavash R, Lomeli, Shirley H, Luebeck, Jens, Goodman, Mark H, Moriceau, Gatien, Krijgsman, Oscar, Dharanipragada, Prashanthi, Ridgley, Trevor, Crosson, William P, Salazar, Jesus, Pazol, Eli, Karin, Gabriel, Jayaraman, Rachana, Balanis, Nikolas G, Alhani, Salwan, Sheu, Kyle, Ten Hoeve, Johanna, Palermo, Amelia, Motika, Stephen E, Senaratne, T Niroshi, Paraiso, Kim H, Hergenrother, Paul J, Rao, P Nagesh, Multani, Asha S, Peeper, Daniel S, Bafna, Vineet, Lo, Roger S, Graeber, Thomas G
Published in Cancer discovery (01.04.2022)
Published in Cancer discovery (01.04.2022)
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Expression of Concern: Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity
Hong, Aayoung, Piva, Marco, Liu, Sixue, Hugo, Willy, Lomeli, Shirley H, Zoete, Vincent, Randolph, Christopher E, Yang, Zhentao, Wang, Yan, Lee, Jordan J, Lo, Skylar J, Sun, Lu, Vega-Crespo, Agustin, Garcia, Alejandro J, Shackelford, David B, Dubinett, Steven M, Scumpia, Philip O, Byrum, Stephanie D, Tackett, Alan J, Donahue, Timothy R, Michielin, Olivier, Holmen, Sheri L, Ribas, Antoni, Moriceau, Gatien, Lo, Roger S
Published in Cancer discovery (01.07.2024)
Published in Cancer discovery (01.07.2024)
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Neoadjuvant presurgical PD-1 inhibition in oral cavity squamous cell carcinoma
Knochelmann, Hannah M., Horton, Joshua D., Liu, Sixue, Armeson, Kent, Kaczmar, John M., Wyatt, Megan M., Richardson, Mary S., Lomeli, Shirley H., Xiong, Ying, Graboyes, Evan M., Lentsch, Eric J., Hornig, Joshua D., Skoner, Judith, Stalcup, Seth, Spampinato, Maria V., Garrett-Mayer, Elizabeth, O’Quinn, Elizabeth C., Timmers, Cynthia D., Romeo, Martin J., Wrangle, John M., Young, M. Rita I., Rubinstein, Mark P., Day, Terry A., Lo, Roger S., Paulos, Chrystal M., Neskey, David M.
Published in Cell reports. Medicine (19.10.2021)
Published in Cell reports. Medicine (19.10.2021)
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Response and recurrence correlates in individuals treated with neoadjuvant anti-PD-1 therapy for resectable oral cavity squamous cell carcinoma
Liu, Sixue, Knochelmann, Hannah M., Lomeli, Shirley H., Hong, Aayoung, Richardson, Mary, Yang, Zhentao, Lim, Raymond J., Wang, Yan, Dumitras, Camelia, Krysan, Kostyantyn, Timmers, Cynthia, Romeo, Martin J., Krieg, Carsten, O’Quinn, Elizabeth C., Horton, Joshua D., Dubinett, Steve M., Paulos, Chrystal M., Neskey, David M., Lo, Roger S.
Published in Cell reports. Medicine (19.10.2021)
Published in Cell reports. Medicine (19.10.2021)
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Sizing Large Proteins and Protein Complexes by Electrospray Ionization Mass Spectrometry and Ion Mobility
Kaddis, Catherine S., Lomeli, Shirley H., Yin, Sheng, Berhane, Beniam, Apostol, Marcin I., Kickhoefer, Valerie A., Rome, Leonard H., Loo, Joseph A.
Published in Journal of the American Society for Mass Spectrometry (01.07.2007)
Published in Journal of the American Society for Mass Spectrometry (01.07.2007)
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Dominant B-cell epitopes from cancer/stem cell antigen SOX2 recognized by serum samples from cancer patients
Shih, Julia, Rahman, Munira, Luong, Quang T, Lomeli, Shirley H, Riss, Joseph, Prins, Robert M, Gure, Ali O, Zeng, Gang
Published in American journal of clinical and experimental immunology (01.01.2014)
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Published in American journal of clinical and experimental immunology (01.01.2014)
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Exploiting Drug Addiction Mechanisms to Select against MAPKi-Resistant Melanoma
Hong, Aayoung, Moriceau, Gatien, Sun, Lu, Lomeli, Shirley, Piva, Marco, Damoiseaux, Robert, Holmen, Sheri L, Sharpless, Norman E, Hugo, Willy, Lo, Roger S
Published in Cancer discovery (01.01.2018)
Published in Cancer discovery (01.01.2018)
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Recurrent Tumor Cell-Intrinsic and -Extrinsic Alterations during MAPKi-Induced Melanoma Regression and Early Adaptation
Song, Chunying, Piva, Marco, Sun, Lu, Hong, Aayoung, Moriceau, Gatien, Kong, Xiangju, Zhang, Hong, Lomeli, Shirley, Qian, Jin, Yu, Clarissa C, Damoiseaux, Robert, Kelley, Mark C, Dahlman, Kimberley B, Scumpia, Philip O, Sosman, Jeffrey A, Johnson, Douglas B, Ribas, Antoni, Hugo, Willy, Lo, Roger S
Published in Cancer discovery (01.11.2017)
Published in Cancer discovery (01.11.2017)
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