High-throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by methylated DNA sequencing (MeD-seq) of LpnPI digested fragments
Deger, Teoman, Boers, Ruben G, de Weerd, Vanja, Angus, Lindsay, van der Put, Marjolijn M J, Boers, Joachim B, Azmani, Z, van IJcken, Wilfred F J, Grünhagen, Dirk J, van Dessel, Lisanne F, Lolkema, Martijn P J K, Verhoef, Cornelis, Sleijfer, Stefan, Martens, John W M, Gribnau, Joost, Wilting, Saskia M
Published in Clinical epigenetics (01.12.2021)
Published in Clinical epigenetics (01.12.2021)
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Impact of panel design and cut-off on tumour mutational burden assessment in metastatic solid tumour samples
Mankor, Joanne M., Paats, Marthe S., Groenendijk, Floris H., Roepman, Paul, Dinjens, Winand N. M., Dubbink, Hendrikus J., Sleijfer, Stefan, Cuppen, Edwin, Lolkema, Martijn P. J. K.
Published in British journal of cancer (01.03.2020)
Published in British journal of cancer (01.03.2020)
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Evaluation of the Khorana, PROTECHT, and 5‐SNP scores for prediction of venous thromboembolism in patients with cancer
Guman, Noori A. M., van Geffen, Roos J., Mulder, Frits I., van Haaps, Thijs F., Hovsepjan, Vahram, Labots, Mariette, Cirkel, Geert A., Y. F. L. de Vos, Filip, ten Tije, Albert J., Beerepoot, Laurens V., Tjan‐Heijnen, Vivianne C. G., van Laarhoven, Hanneke W. M., Hamberg, Paul, Vulink, Annelie J. E., Los, Maartje, Zwinderman, Aeilko H., Ferwerda, Bart, Lolkema, Martijn P. J. K., Steeghs, Neeltje, Büller, Harry R., Kamphuisen, Pieter W., van Es, Nick
Published in Journal of thrombosis and haemostasis (01.12.2021)
Published in Journal of thrombosis and haemostasis (01.12.2021)
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Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer
van Geel, Robin M. J. M., van Brummelen, Emilie M. J., Eskens, Ferry A. L. M., Huijberts, Sanne C. F. A., de Vos, Filip Y. F. L., Lolkema, Martijn P. J. K., Devriese, Lot A., Opdam, Frans L., Marchetti, Serena, Steeghs, Neeltje, Monkhorst, Kim, Thijssen, Bas, Rosing, Hilde, Huitema, Alwin D. R., Beijnen, Jos H., Bernards, René, Schellens, Jan H. M.
Published in British journal of cancer (01.04.2020)
Published in British journal of cancer (01.04.2020)
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Risk of Thromboembolic Events after Perioperative Chemotherapy Versus Surgery Alone for Esophageal Adenocarcinoma
Verhage, Roy J. J., van der Horst, Sylvia, van der Sluis, Pieter C., Lolkema, Martijn P. J. K., van Hillegersberg, Richard
Published in Annals of surgical oncology (01.02.2012)
Published in Annals of surgical oncology (01.02.2012)
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Consensus molecular subtype 4 (CMS4)-targeted therapy in primary colon cancer: A proof-of-concept study
Peters, Niek A., Constantinides, Alexander, Ubink, Inge, van Kuik, Joyce, Bloemendal, Haiko J., van Dodewaard, Joyce M., Brink, Menno A., Schwartz, Thijs P., Lolkema, Martijn P.J.K., Lacle, Miangela M., Moons, Leon M., Geesing, Joost, van Grevenstein, Wilhelmina M.U., Roodhart, Jeanine M. L., Koopman, Miriam, Elias, Sjoerd G., Borel Rinkes, Inne H.M., Kranenburg, Onno
Published in Frontiers in oncology (06.09.2022)
Published in Frontiers in oncology (06.09.2022)
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CAST: A retrospective analysis of cabazitaxel and abiraterone acetate sequential treatment in patients with metastatic castrate‐resistant prostate cancer previously treated with docetaxel
Wissing, Michel D., Coenen, Jules L.L.M., van den Berg, Pieter, Westgeest, Hans M., van den Eertwegh, Alfons J.M., van Oort, Inge M., Bos, Monique M., Bergman, André M., Hamberg, Paul, ten Tije, Albert J., Los, Maartje, Lolkema, Martijn P.J.K., de Wit, Ronald, Gelderblom, Hans
Published in International journal of cancer (15.03.2015)
Published in International journal of cancer (15.03.2015)
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Abstract 5673: In-depth analysis of the genomic landscape of 91 metastatic neuroendocrine tumors reveals subtype-heterogeneity and potential therapeutic targets
van Riet, Job, van de Werken, Harmen J., Cuppen, Edwin, Eskens, Ferry A. L. M., Tesselaar, Margot E., van Veenendaal, Linde M., Klümpen, Heinz-Josef, Dercksen, Wouter, Valk, Gerlof D., Lolkema, Martijn P. J. K., Sleijfer, Stefan, Mostert, Bianca
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Robot-assisted minimally invasive thoraco-laparoscopic esophagectomy versus open transthoracic esophagectomy for resectable esophageal cancer, a randomized controlled trial (ROBOT trial)
van der Sluis, Pieter C, Ruurda, Jelle P, van der Horst, Sylvia, Verhage, Roy J J, Besselink, Marc G H, Prins, Margriet J D, Haverkamp, Leonie, Schippers, Carlo, Rinkes, Inne H M Borel, Joore, Hans C A, Ten Kate, Fiebo Jw, Koffijberg, Hendrik, Kroese, Christiaan C, van Leeuwen, Maarten S, Lolkema, Martijn P J K, Reerink, Onne, Schipper, Marguerite E I, Steenhagen, Elles, Vleggaar, Frank P, Voest, Emile E, Siersema, Peter D, van Hillegersberg, Richard
Published in Current controlled trials in cardiovascular medicine (30.11.2012)
Published in Current controlled trials in cardiovascular medicine (30.11.2012)
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A phase 1b/2 study of LEE011 in combination with binimetinib (MEK162) in patients with NRAS -mutant melanoma: Early encouraging clinical activity
Sosman, Jeffrey Alan, Kittaneh, Muaiad, Lolkema, Martijn P. J. K., Postow, Michael Andrew, Schwartz, Gary, Franklin, Catherine, Matano, Alessandro, Bhansali, Suraj, Parasuraman, Sudha, Kim, Kevin
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Association analysis of polymorphisms in genes related to sunitinib pharmacokinetics
Diekstra, Meta, Klümpen, Heinz Josef, Lolkema, Martijn P. J. K., Yu, Huixin, Kloth, Jacqueline S.L., Gelderblom, Hans, van Schaik, Ron H.N., Gurney, Howard, Swen, Jesse J, Huitema, Alwin D.R., Steeghs, Neeltje, Mathijssen, Ron H.J.
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Phase I study of the selective BRAF V600 inhibitor encorafenib (LGX818) combined with cetuximab and with or without the α-specific PI3K inhibitor BYL719 in patients with advanced BRAF -mutant colorectal cancer
Geel, Robin Van, Elez, Elena, Bendell, Johanna C., Faris, Jason Edward, Lolkema, Martijn P. J. K., Eskens, Ferry, Spreafico, Anna, Kavan, Petr, Delord, Jean-Pierre, Schuler, Martin H., Wainberg, Zev A., Yamada, Yasuhide, Yoshino, Takayuki, Demuth, Tim, Avsar, Emin, Chatterjee, Arkendu, Zhu, Peijuan, Bernards, Rene, Tabernero, Josep, Schellens, Jan HM
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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A first-in-human trial of RG7116, a glycoengineered monoclonal antibody targeting HER3, in patients with advanced/metastatic tumors of epithelial cell origin expressing HER3 protein
Meulendijks, Didier, Lolkema, Martijn P. J. K., Voest, Emile E., De Jonge, Maja J., Sleijfer, Stefan, Schellens, Jan HM, Fleitas, Tania, Cervantes-Ruiperez, Andres, Martinez-Garcia, Maria, Taus, Alvaro, Soerensen, Morten Mau, Thomas, Marlene, Meneses-Lorente, Georgina, Adessi, Celine, Di Scala, Lilla, Keelara, Abiraj, Jacob, Wolfgang, Weisser, Martin, Lassen, Ulrik Niels
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Phase I study of safety, tolerability, and pharmacokinetics of pazopanib in combination with oral topotecan in patients with advanced solid tumors
Milojkovic Kerklaan, Bojana, Lolkema, Martijn P. J. K., Devriese, Lot A., Voest, Emile E., Nol-Boekel, A., Mergui-Roelvink, M., Mykulowycz, Kristine, Stoebenau, Joseph E, Fang, Lei, Legenne, Philippe, Wissel, Paul Stephen, Smith, Deborah A., Giantonio, Bruce J., Schellens, Jan HM, Witteveen, Petronella
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Journal Article
Fibronectin is a hypoxia-independent target of the tumor suppressor VHL
Bluyssen, Hans A.R., Lolkema, Martijn P.J.K., van Beest, Moniek, Boone, Michelle, Snijckers, Cristel M.J.T., Los, Maartje, Gebbink, Martijn F.B.G., Braam, Branko, Holstege, Frank C.P., Giles, Rachel H., Voest, Emile E.
Published in FEBS letters (02.01.2004)
Published in FEBS letters (02.01.2004)
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