DNA replication stress: Causes, resolution and disease
Mazouzi, Abdelghani, Velimezi, Georgia, Loizou, Joanna I.
Published in Experimental cell research (15.11.2014)
Published in Experimental cell research (15.11.2014)
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Validating the concept of mutational signatures with isogenic cell models
Zou, Xueqing, Owusu, Michel, Harris, Rebecca, Jackson, Stephen P., Loizou, Joanna I., Nik-Zainal, Serena
Published in Nature communications (01.05.2018)
Published in Nature communications (01.05.2018)
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Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy
Huber, Kilian V. M., Salah, Eidarus, Radic, Branka, Gridling, Manuela, Elkins, Jonathan M., Stukalov, Alexey, Jemth, Ann-Sofie, Göktürk, Camilla, Sanjiv, Kumar, Strömberg, Kia, Pham, Therese, Berglund, Ulrika Warpman, Colinge, Jacques, Bennett, Keiryn L., Loizou, Joanna I., Helleday, Thomas, Knapp, Stefan, Superti-Furga, Giulio
Published in Nature (London) (10.04.2014)
Published in Nature (London) (10.04.2014)
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Tissue Specific DNA Repair Outcomes Shape the Landscape of Genome Editing
Meyenberg, Mathilde, Ferreira da Silva, Joana, Loizou, Joanna I
Published in Frontiers in genetics (03.09.2021)
Published in Frontiers in genetics (03.09.2021)
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Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis
Serwas, Nina K., Hoeger, Birgit, Ardy, Rico C., Stulz, Sigrun V., Sui, Zhenhua, Memaran, Nima, Meeths, Marie, Krolo, Ana, Yüce Petronczki, Özlem, Pfajfer, Laurène, Hou, Tie Z., Halliday, Neil, Santos-Valente, Elisangela, Kalinichenko, Artem, Kennedy, Alan, Mace, Emily M., Mukherjee, Malini, Tesi, Bianca, Schrempf, Anna, Pickl, Winfried F., Loizou, Joanna I., Kain, Renate, Bidmon-Fliegenschnee, Bettina, Schickel, Jean-Nicolas, Glauzy, Salomé, Huemer, Jakob, Garncarz, Wojciech, Salzer, Elisabeth, Pierides, Iro, Bilic, Ivan, Thiel, Jens, Priftakis, Peter, Banerjee, Pinaki P., Förster-Waldl, Elisabeth, Medgyesi, David, Huber, Wolf-Dietrich, Orange, Jordan S., Meffre, Eric, Sansom, David M., Bryceson, Yenan T., Altman, Amnon, Boztug, Kaan
Published in Nature communications (15.07.2019)
Published in Nature communications (15.07.2019)
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FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair
Kratz, Katja, Artola-Borán, Mariela, Kobayashi-Era, Saho, Koh, Gene, Oliveira, Goncalo, Kobayashi, Shunsuke, Oliveira, Andreia, Zou, Xueqing, Richter, Julia, Tsuda, Masataka, Sasanuma, Hiroyuki, Takeda, Shunichi, Loizou, Joanna I., Sartori, Alessandro A., Nik-Zainal, Serena, Jiricny, Josef
Published in Molecular and cellular biology (01.09.2021)
Published in Molecular and cellular biology (01.09.2021)
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A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability
Moretton, Amandine, Kourtis, Savvas, Gañez Zapater, Antoni, Calabrò, Chiara, Espinar Calvo, Maria Lorena, Fontaine, Frédéric, Darai, Evangelia, Abad Cortel, Etna, Block, Samuel, Pascual‐Reguant, Laura, Pardo‐Lorente, Natalia, Ghose, Ritobrata, Vander Heiden, Matthew G, Janic, Ana, Müller, André C, Loizou, Joanna I, Sdelci, Sara
Published in Molecular systems biology (11.07.2023)
Published in Molecular systems biology (11.07.2023)
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Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH
Mazouzi, Abdelghani, Battistini, Federica, Moser, Sarah C., Ferreira da Silva, Joana, Wiedner, Marc, Owusu, Michel, Lardeau, Charles-Hugues, Ringler, Anna, Weil, Beatrix, Neesen, Jürgen, Orozco, Modesto, Kubicek, Stefan, Loizou, Joanna I.
Published in Molecular cell (16.11.2017)
Published in Molecular cell (16.11.2017)
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Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48
Velimezi, Georgia, Robinson-Garcia, Lydia, Muñoz-Martínez, Francisco, Wiegant, Wouter W., Ferreira da Silva, Joana, Owusu, Michel, Moder, Martin, Wiedner, Marc, Rosenthal, Sara Brin, Fisch, Kathleen M., Moffat, Jason, Menche, Jörg, van Attikum, Haico, Jackson, Stephen P., Loizou, Joanna I.
Published in Nature communications (11.06.2018)
Published in Nature communications (11.06.2018)
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High activation of STAT5A drives peripheral T-cell lymphoma and leukemia
Maurer, Barbara, Nivarthi, Harini, Wingelhofer, Bettina, Pham, Ha Thi Thanh, Schlederer, Michaela, Suske, Tobias, Grausenburger, Reinhard, Schiefer, Ana-Iris, Prchal-Murphy, Michaela, Chen, Doris, Winkler, Susanne, Merkel, Olaf, Kornauth, Christoph, Hofbauer, Maximilian, Hochgatterer, Birgit, Hoermann, Gregor, Hoelbl-Kovacic, Andrea, Prochazkova, Jana, Lobello, Cosimo, Cumaraswamy, Abbarna A, Latzka, Johanna, Kitzwögerer, Melitta, Chott, Andreas, Janikova, Andrea, Pospíšilova, Šárka, Loizou, Joanna I, Kubicek, Stefan, Valent, Peter, Kolbe, Thomas, Grebien, Florian, Kenner, Lukas, Gunning, Patrick T, Kralovics, Robert, Herling, Marco, Müller, Mathias, Rülicke, Thomas, Sexl, Veronika, Moriggl, Richard
Published in Haematologica (Roma) (01.02.2020)
Published in Haematologica (Roma) (01.02.2020)
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Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet
Meyenberg, Mathilde, Hakobyan, Anna, Papac-Milicevic, Nikolina, Göderle, Laura, Langner, Franziska L., Markovic, Mateo, Lee, Ji-Hyun, Koo, Bon-Kyoung, Busslinger, Georg A., da Silva, Israel Tojal, Binder, Christoph J., Menche, Jörg, Loizou, Joanna I.
Published in Scientific reports (26.08.2023)
Published in Scientific reports (26.08.2023)
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MEK inhibitors block growth of lung tumours with mutations in ataxia–telangiectasia mutated
Smida, Michal, Fece de la Cruz, Ferran, Kerzendorfer, Claudia, Uras, Iris Z., Mair, Barbara, Mazouzi, Abdelghani, Suchankova, Tereza, Konopka, Tomasz, Katz, Amanda M., Paz, Keren, Nagy-Bojarszky, Katalin, Muellner, Markus K., Bago-Horvath, Zsuzsanna, Haura, Eric B., Loizou, Joanna I., Nijman, Sebastian M. B.
Published in Nature communications (06.12.2016)
Published in Nature communications (06.12.2016)
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A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN
Mazouzi, Abdelghani, Stukalov, Alexey, Müller, André C., Chen, Doris, Wiedner, Marc, Prochazkova, Jana, Chiang, Shih-Chieh, Schuster, Michael, Breitwieser, Florian P., Pichlmair, Andreas, El-Khamisy, Sherif F., Bock, Christoph, Kralovics, Robert, Colinge, Jacques, Bennett, Keiryn L., Loizou, Joanna I.
Published in Cell reports (Cambridge) (26.04.2016)
Published in Cell reports (Cambridge) (26.04.2016)
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Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia
Moder, Martin, Velimezi, Georgia, Owusu, Michel, Mazouzi, Abdelghani, Wiedner, Marc, Ferreira da Silva, Joana, Robinson-Garcia, Lydia, Schischlik, Fiorella, Slavkovsky, Rastislav, Kralovics, Robert, Schuster, Michael, Bock, Christoph, Ideker, Trey, Jackson, Stephen P., Menche, Jörg, Loizou, Joanna I.
Published in Nature communications (01.11.2017)
Published in Nature communications (01.11.2017)
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Pan-cancer analysis of the interplay between mutational signatures and cellular signaling
Hakobyan, Anna, Meyenberg, Mathilde, Vardazaryan, Nelli, Hancock, Joel, Vulliard, Loan, Loizou, Joanna I., Menche, Jörg
Published in iScience (21.06.2024)
Published in iScience (21.06.2024)
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