Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder
Galvani, Giuseppe, Mottolese, Nicola, Gennaccaro, Laura, Loi, Manuela, Medici, Giorgio, Tassinari, Marianna, Fuchs, Claudia, Ciani, Elisabetta, Trazzi, Stefania
Published in Journal of neuroinflammation (08.07.2021)
Published in Journal of neuroinflammation (08.07.2021)
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Journal Article
Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder
Tassinari, Marianna, Mottolese, Nicola, Galvani, Giuseppe, Ferrara, Domenico, Gennaccaro, Laura, Loi, Manuela, Medici, Giorgio, Candini, Giulia, Rimondini, Roberto, Ciani, Elisabetta, Trazzi, Stefania
Published in International journal of molecular sciences (01.08.2022)
Published in International journal of molecular sciences (01.08.2022)
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Journal Article
CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling
Fuchs, Claudia, Medici, Giorgio, Trazzi, Stefania, Gennaccaro, Laura, Galvani, Giuseppe, Berteotti, Chiara, Ren, Elisa, Loi, Manuela, Ciani, Elisabetta
Published in Brain pathology (Zurich, Switzerland) (01.09.2019)
Published in Brain pathology (Zurich, Switzerland) (01.09.2019)
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Journal Article
Early-onset brain alterations during postnatal development in a mouse model of CDKL5 deficiency disorder
Tassinari, Marianna, Uguagliati, Beatrice, Trazzi, Stefania, Cerchier, Camilla Bruna, Cavina, Ottavia Vera, Mottolese, Nicola, Loi, Manuela, Candini, Giulia, Medici, Giorgio, Ciani, Elisabetta
Published in Neurobiology of disease (15.06.2023)
Published in Neurobiology of disease (15.06.2023)
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Journal Article
Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons
Loi, Manuela, Trazzi, Stefania, Fuchs, Claudia, Galvani, Giuseppe, Medici, Giorgio, Gennaccaro, Laura, Tassinari, Marianna, Ciani, Elisabetta
Published in Molecular neurobiology (01.05.2020)
Published in Molecular neurobiology (01.05.2020)
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Journal Article
A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder
Gennaccaro, Laura, Fuchs, Claudia, Loi, Manuela, Roncacè, Vincenzo, Trazzi, Stefania, Ait-Bali, Yassine, Galvani, Giuseppe, Berardi, Anna Cecilia, Medici, Giorgio, Tassinari, Marianna, Ren, Elisa, Rimondini, Roberto, Giustetto, Maurizio, Aicardi, Giorgio, Ciani, Elisabetta
Published in Neurobiology of disease (01.06.2021)
Published in Neurobiology of disease (01.06.2021)
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Journal Article
Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder
Loi, Manuela, Gennaccaro, Laura, Fuchs, Claudia, Trazzi, Stefania, Medici, Giorgio, Galvani, Giuseppe, Mottolese, Nicola, Tassinari, Marianna, Giorgini, Roberto Rimondini, Milelli, Andrea, Ciani, Elisabetta
Published in International journal of molecular sciences (31.05.2021)
Published in International journal of molecular sciences (31.05.2021)
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Journal Article
Functional and Structural Impairments in the Perirhinal Cortex of a Mouse Model of CDKL5 Deficiency Disorder Are Rescued by a TrkB Agonist
Ren, Elisa, Roncacé, Vincenzo, Trazzi, Stefania, Fuchs, Claudia, Medici, Giorgio, Gennaccaro, Laura, Loi, Manuela, Galvani, Giuseppe, Ye, Keqiang, Rimondini, Roberto, Aicardi, Giorgio, Ciani, Elisabetta
Published in Frontiers in cellular neuroscience (30.04.2019)
Published in Frontiers in cellular neuroscience (30.04.2019)
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Journal Article
Cardiac Functional and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder
Loi, Manuela, Bastianini, Stefano, Candini, Giulia, Rizzardi, Nicola, Medici, Giorgio, Papa, Valentina, Gennaccaro, Laura, Mottolese, Nicola, Tassinari, Marianna, Uguagliati, Beatrice, Berteotti, Chiara, Martire, Viviana Lo, Zoccoli, Giovanna, Cenacchi, Giovanna, Trazzi, Stefania, Bergamini, Christian, Ciani, Elisabetta
Published in International journal of molecular sciences (01.03.2023)
Published in International journal of molecular sciences (01.03.2023)
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Journal Article
Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning
Pellegrini, Camilla, Columbaro, Marta, Schena, Elisa, Prencipe, Sabino, Andrenacci, Davide, Iozzo, Patricia, Angela Guzzardi, Maria, Capanni, Cristina, Mattioli, Elisabetta, Loi, Manuela, Araujo-Vilar, David, Squarzoni, Stefano, Cinti, Saverio, Morselli, Paolo, Giorgetti, Assuero, Zanotti, Laura, Gambineri, Alessandra, Lattanzi, Giovanna
Published in Experimental & molecular medicine (02.08.2019)
Published in Experimental & molecular medicine (02.08.2019)
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Journal Article
Voluntary Running Improves Behavioral and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder
Mottolese, Nicola, Uguagliati, Beatrice, Tassinari, Marianna, Cerchier, Camilla Bruna, Loi, Manuela, Candini, Giulia, Rimondini, Roberto, Medici, Giorgio, Trazzi, Stefania, Ciani, Elisabetta
Published in Biomolecules (Basel, Switzerland) (01.09.2023)
Published in Biomolecules (Basel, Switzerland) (01.09.2023)
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Journal Article
Emerin Phosphorylation during the Early Phase of the Oxidative Stress Response Influences Emerin-BAF Interaction and BAF Nuclear Localization
Cenni, Vittoria, Squarzoni, Stefano, Loi, Manuela, Mattioli, Elisabetta, Lattanzi, Giovanna, Capanni, Cristina
Published in Cells (Basel, Switzerland) (06.06.2020)
Published in Cells (Basel, Switzerland) (06.06.2020)
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Journal Article
Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder
Fuchs, Claudia, Gennaccaro, Laura, Ren, Elisa, Galvani, Giuseppe, Trazzi, Stefania, Medici, Giorgio, Loi, Manuela, Conway, Erin, Devinsky, Orrin, Rimondini, Roberto, Ciani, Elisabetta
Published in Neuropharmacology (01.05.2020)
Published in Neuropharmacology (01.05.2020)
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Journal Article
Barrier-to-autointegration factor (BAF) involvement in prelamin A-related chromatin organization changes
Loi, Manuela, Cenni, Vittoria, Duchi, Serena, Squarzoni, Stefano, Lopez-Otin, Carlos, Foisner, Roland, Lattanzi, Giovanna, Capanni, Cristina
Published in Oncotarget (29.03.2016)
Published in Oncotarget (29.03.2016)
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Journal Article
Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder
Medici, Giorgio, Tassinari, Marianna, Galvani, Giuseppe, Bastianini, Stefano, Gennaccaro, Laura, Loi, Manuela, Mottolese, Nicola, Alvente, Sara, Berteotti, Chiara, Sagona, Giulia, Lupori, Leonardo, Candini, Giulia, Baggett, Helen Rappe, Zoccoli, Giovanna, Giustetto, Maurizio, Muotri, Alysson, Pizzorusso, Tommaso, Nakai, Hiroyuki, Trazzi, Stefania, Ciani, Elisabetta
Published in Neurotherapeutics (01.10.2022)
Published in Neurotherapeutics (01.10.2022)
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Journal Article
Long term breeding of the Lmna G609G progeric mouse: Characterization of homozygous and heterozygous models
Zaghini, Anna, Sarli, Giuseppe, Barboni, Catia, Sanapo, Mara, Pellegrino, Valeria, Diana, Alessia, Linta, Nikolina, Rambaldi, Julie, D'Apice, Maria Rosaria, Murdocca, Michela, Baleani, Massimiliano, Baruffaldi, Fabio, Fognani, Roberta, Mecca, Rosaria, Festa, Anna, Papparella, Serenella, Paciello, Orlando, Prisco, Francesco, Capanni, Cristina, Loi, Manuela, Schena, Elisa, Lattanzi, Giovanna, Squarzoni, Stefano
Published in Experimental gerontology (01.02.2020)
Published in Experimental gerontology (01.02.2020)
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Journal Article
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease
Santini, Alan, Tassinari, Elisa, Poeta, Eleonora, Loi, Manuela, Ciani, Elisabetta, Trazzi, Stefania, Piccarducci, Rebecca, Daniele, Simona, Martini, Claudia, Pagliarani, Barbara, Tarozzi, Andrea, Bersani, Matteo, Spyrakis, Francesca, Danková, Daniela, Olsen, Christian A., Soldati, Roberto, Tumiatti, Vincenzo, Montanari, Serena, De Simone, Angela, Milelli, Andrea
Published in ACS chemical neuroscience (05.06.2024)
Published in ACS chemical neuroscience (05.06.2024)
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Journal Article
Age-Related Cognitive and Motor Decline in a Mouse Model of CDKL5 Deficiency Disorder is Associated with Increased Neuronal Senescence and Death
Gennaccaro, Laura, Fuchs, Claudia, Loi, Manuela, Pizzo, Riccardo, Alvente, Sara, Berteotti, Chiara, Lupori, Leonardo, Sagona, Giulia, Galvani, Giuseppe, Gurgone, Antonia, Raspanti, Alessandra, Medici, Giorgio, Tassinari, Marianna, Trazzi, Stefania, Ren, Elisa, Rimondini, Roberto, Pizzorusso, Tommaso, Zoccoli, Giovanna, Giustetto, Maurizio, Ciani, Elisabetta
Published in Aging and disease (01.06.2021)
Published in Aging and disease (01.06.2021)
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Journal Article
A GABA B receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder
Gennaccaro, Laura, Fuchs, Claudia, Loi, Manuela, Roncacè, Vincenzo, Trazzi, Stefania, Ait-Bali, Yassine, Galvani, Giuseppe, Berardi, Anna Cecilia, Medici, Giorgio, Tassinari, Marianna, Ren, Elisa, Rimondini, Roberto, Giustetto, Maurizio, Aicardi, Giorgio, Ciani, Elisabetta
Published in Neurobiology of disease (01.06.2021)
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Published in Neurobiology of disease (01.06.2021)
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