Physicochemical Properties, Form, and Formulation Selection Strategy for a Biopharmaceutical Classification System Class II Preclinical Drug Candidate
Lohani, Sachin, Cooper, Harriet, Jin, Xiaoling, Nissley, Becky P., Manser, Kimberly, Rakes, Linda Huong, Cummings, John J., Fauty, Scott E., Bak, Annette
Published in Journal of pharmaceutical sciences (01.10.2014)
Published in Journal of pharmaceutical sciences (01.10.2014)
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Journal Article
Spectroscopic Characterization of Molecular Aggregates in Solutions: Impact on Crystallization of Indomethacin Polymorphs from Acetonitrile and Ethanol
Lohani, Sachin, Nesmelova, Irina V, Suryanarayanan, Raj, Grant, David J.W
Published in Crystal growth & design (01.06.2011)
Published in Crystal growth & design (01.06.2011)
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Journal Article
Development and validation of a GC method for a key nemtabrutinib intermediate: Implementation of an in-situ free base sample preparation protocol
Rivera, Nelo R., Zewge, Daniel, Arvary, Rebecca, Lin, Mingxiang, Lohani, Sachin
Published in Journal of pharmaceutical and biomedical analysis (15.04.2024)
Published in Journal of pharmaceutical and biomedical analysis (15.04.2024)
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Journal Article
Challenges with retention and recovery of impurities containing acidic moieties during analytical UHPLC method development and validation for gefapixant freebase
Halsey, Holst, Hall, Jackson, Huang, Chunli, Liu, Wenjun, Parganiha, Priya, Song, Siqing, Duran-Capece, Alicia, Fett, Joseph, Mathkar, Shilpa, Lohani, Sachin
Published in Journal of pharmaceutical and biomedical analysis (05.01.2024)
Published in Journal of pharmaceutical and biomedical analysis (05.01.2024)
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Journal Article
Universal ion chromatography method for anions in active pharmaceutical ingredients enabled by computer-assisted separation modeling
Yuan, Tianyu, Merai, Dolee, Gunsch, Matthew J., Peters, Ryan, Lohani, Sachin, Bernardoni, Frank, Zompa, Michael A., Ahmad, Imad Haidar, Regalado, Erik L., Pohl, Christopher A.
Published in Journal of pharmaceutical and biomedical analysis (15.04.2024)
Published in Journal of pharmaceutical and biomedical analysis (15.04.2024)
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Journal Article
Development of a derivatization RP-HPLC method for determination of sulfuryl chloride in chlorosulfonic acid for gefapixant citrate manufacture
Huang, Chunli, Song, Siqing, Liu, Wenjun, Parganiha, Priya, Zhuang, Ping, Lohani, Sachin, Alwedi, Embarek, Ren, Hong, Bishara, Daniel, Chang, Hsieh Yao D.
Published in Journal of pharmaceutical and biomedical analysis (05.06.2022)
Published in Journal of pharmaceutical and biomedical analysis (05.06.2022)
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Journal Article
Gefapixant Citrate (MK-7264) Sulfonamide Step Speciation Study: Investigation into Precipitation–Dissolution Events during Addition of Chlorosulfonic Acid
Rivera, Nelo R., Cohen, Ryan D., Zhang, Si-Wei, Dance, Zachary E. X., Halsey, Holst M., Song, Siqing, Bu, Xiaodong, Reibarkh, Mikhail, Ren, Hong, Lee, Alfred Y., Chang, Darryl, Lohani, Sachin
Published in Organic process research & development (17.02.2023)
Published in Organic process research & development (17.02.2023)
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Journal Article
A Holistic Strategy for Cyanide Control and Safety for Pharmaceutical Manufacturing
Zompa, Michael A, Di Maso, Michael J, Guzman, Francisco, Zhao, Ralph, Jellett, Lisa, Arvary, Rebecca, Song, Siqing, Chang, Darryl, Ren, Hong, Lohani, Sachin
Published in Organic process research & development (20.08.2021)
Published in Organic process research & development (20.08.2021)
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Journal Article
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 1: Introduction and Process Overview
Ren, Hong, Maloney, Kevin M, Basu, Kallol, Di Maso, Michael J, Humphrey, Guy R, Peng, Feng, Desmond, Richard, Otte, Douglas A. L, Alwedi, Embarek, Liu, Wenjun, Zhang, Si-Wei, Song, Siqing, Arvary, Rebecca A, Zompa, Michael A, Lehnherr, Dan, Martin, Gary E, Chang, Hsieh Yao D, Mohan, Anne E, Guzman, Francisco J, Jellett, Lisa, Lee, Alfred Y, Spencer, Glenn, Fisher, Elizabeth S, Naber, John R, Gao, Hong, Lohani, Sachin, Ruck, Rebecca T, Campeau, Louis-Charles
Published in Organic process research & development (20.11.2020)
Published in Organic process research & development (20.11.2020)
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Journal Article
Generic reversed‐phase ultra‐high‐pressure liquid chromatography methodology developed by using computer‐assisted modeling for streamlined performance evaluation of a wide range of stationary phase columns
Ahmad, Imad A. Haidar, Losacco, Gioacchino Luca, Figus, Margaret, Korani, Deepa, Gunsch, Matthew J., Lhotka, Hayley R., Hullen, Kari, Hartman, Robert, Lohani, Sachin, Hamilton, Simon, Mangion, Ian, Regalado, Erik L.
Published in Separation science plus (01.05.2022)
Published in Separation science plus (01.05.2022)
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Journal Article
Front Cover: Generic reversed‐phase ultra‐high‐pressure liquid chromatography methodology developed by using computer‐assisted modeling for streamlined performance evaluation of a wide range of stationary phase columns
Ahmad, Imad A. Haidar, Losacco, Gioacchino Luca, Figus, Margaret, Korani, Deepa, Gunsch, Matthew J., Lhotka, Hayley R., Hullen, Kari, Hartman, Robert, Lohani, Sachin, Hamilton, Simon, Mangion, Ian, Regalado, Erik L.
Published in Separation science plus (01.05.2022)
Published in Separation science plus (01.05.2022)
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Journal Article
Syntheses of T N building blocks N α-(9-fluorenylmethoxycarbonyl)- O-(3,4,6-tri- O-acetyl-2-azido-2-deoxy-α- d-galactopyranosyl)- l-serine/ l-threonine pentafluorophenyl esters: comparison of protocols and elucidation of side reactions
Liu, Mian, Young, Victor G., Lohani, Sachin, Live, David, Barany, George
Published in Carbohydrate research (23.05.2005)
Published in Carbohydrate research (23.05.2005)
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Journal Article
Syntheses of T(N) building blocks Nalpha-(9-fluorenylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-azido-2-deoxy-alpha-D-galactopyranosyl)-L-serine/L-threonine pentafluorophenyl esters: comparison of protocols and elucidation of side reactions
Liu, Mian, Young, Jr, Victor G, Lohani, Sachin, Live, David, Barany, George
Published in Carbohydrate research (23.05.2005)
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Published in Carbohydrate research (23.05.2005)
Journal Article
Syntheses of TN building blocks Nα-(9-fluorenylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-d-galactopyranosyl)-l-serine/l-threonine pentafluorophenyl esters: comparison of protocols and elucidation of side reactions
Liu, Mian, Young, Victor G., Lohani, Sachin, Live, David, Barany, George
Published in Carbohydrate research (01.05.2005)
Published in Carbohydrate research (01.05.2005)
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Journal Article