International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data
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An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
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Published in Science (American Association for the Advancement of Science) (12.12.2014)
Published in Science (American Association for the Advancement of Science) (12.12.2014)
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Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment
Dong, Lei, Yu, Wen-Mei, Zheng, Hong, Loh, Mignon L, Bunting, Silvia T, Pauly, Melinda, Huang, Gang, Zhou, Muxiang, Broxmeyer, Hal E, Scadden, David T, Qu, Cheng-Kui
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Impact of Asparaginase Discontinuation on Outcome in Childhood Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group
Gupta, Sumit, Wang, Cindy, Raetz, Elizabeth A, Schore, Reuven, Salzer, Wanda L, Larsen, Eric C, Maloney, Kelly W, Mattano, Jr, Len A, Carroll, William L, Winick, Naomi J, Hunger, Stephen P, Loh, Mignon L, Devidas, Meenakshi
Published in Journal of clinical oncology (10.06.2020)
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Prognostic significance of minimal residual disease in high risk B-ALL: a report from Children's Oncology Group study AALL0232
Borowitz, Michael J., Wood, Brent L., Devidas, Meenakshi, Loh, Mignon L., Raetz, Elizabeth A., Salzer, Wanda L., Nachman, James B., Carroll, Andrew J., Heerema, Nyla A., Gastier-Foster, Julie M., Willman, Cheryl L., Dai, Yunfeng, Winick, Naomi J., Hunger, Stephen P., Carroll, William L., Larsen, Eric
Published in Blood (20.08.2015)
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Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia
Tasian, Sarah K., Teachey, David T., Li, Yong, Shen, Feng, Harvey, Richard C., Chen, I-Ming, Ryan, Theresa, Vincent, Tiffaney L., Willman, Cheryl L., Perl, Alexander E., Hunger, Stephen P., Loh, Mignon L., Carroll, Martin, Grupp, Stephan A.
Published in Blood (12.01.2017)
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Detection of Minimal Residual Disease in B Lymphoblastic Leukemia by High-Throughput Sequencing of IGH
WU, David, EMERSON, Ryan O, WILLIAMSON, David, WOOD, Brent L, ROBINS, Harlan, SHERWOOD, Anna, LOH, Mignon L, ANGIOLILLO, Anne, HOWIE, Bryan, VOGT, Jennifer, RIEDER, Mark, KIRSCH, Ilan, CARLSON, Christopher
Published in Clinical cancer research (01.09.2014)
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Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia
Oshima, Koichi, Khiabanian, Hossein, da Silva-Almeida, Ana C., Tzoneva, Gannie, Abate, Francesco, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Carpenter, Zachary, Penson, Alex, Perez-Garcia, Arianne, Eckert, Cornelia, Nicolas, Concepción, Balbin, Milagros, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Devidas, Meenakshi, Loh, Mignon L., Kirschner-Schwabe, Renate, Palomero, Teresa, Rabadan, Raul, Ferrando, Adolfo A.
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2016)
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FLT3 inhibitor lestaurtinib plus chemotherapy for newly diagnosed KMT2A-rearranged infant acute lymphoblastic leukemia: Children's Oncology Group trial AALL0631
Brown, Patrick A, Kairalla, John A, Hilden, Joanne M, Dreyer, ZoAnn E, Carroll, Andrew J, Heerema, Nyla A, Wang, Cindy, Devidas, Meenakshi, Gore, Lia, Salzer, Wanda L, Winick, Naomi J, Carroll, William L, Raetz, Elizabeth A, Borowitz, Michael J, Small, Donald, Loh, Mignon L, Hunger, Stephen P
Published in Leukemia (01.05.2021)
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International Consensus Definition of DNA Methylation Subgroups in Juvenile Myelomonocytic Leukemia
Schönung, Maximilian, Meyer, Julia, Nöllke, Peter, Olshen, Adam B, Hartmann, Mark, Murakami, Norihiro, Wakamatsu, Manabu, Okuno, Yusuke, Plass, Christoph, Loh, Mignon L, Niemeyer, Charlotte M, Muramatsu, Hideki, Flotho, Christian, Stieglitz, Elliot, Lipka, Daniel B
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Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia
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Published in Nature communications (19.12.2017)
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Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia
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Published in Blood (25.10.2012)
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Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk
Vijayakrishnan, Jayaram, Qian, Maoxiang, Studd, James B, Yang, Wenjian, Kinnersley, Ben, Law, Philip J, Broderick, Peter, Raetz, Elizabeth A, Allan, James, Pui, Ching-Hon, Vora, Ajay, Evans, William E, Moorman, Anthony, Yeoh, Allen, Yang, Wentao, Li, Chunliang, Bartram, Claus R, Mullighan, Charles G, Zimmerman, Martin, Hunger, Stephen P, Schrappe, Martin, Relling, Mary V, Stanulla, Martin, Loh, Mignon L, Houlston, Richard S, Yang, Jun J
Published in Nature communications (25.11.2019)
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Mutation-specific signaling profiles and kinase inhibitor sensitivities of juvenile myelomonocytic leukemia revealed by induced pluripotent stem cells
Tasian, Sarah K, Casas, Jessica A, Posocco, David, Gandre-Babbe, Shilpa, Gagne, Alyssa L, Liang, Ge, Loh, Mignon L, Weiss, Mitchell J, French, Deborah L, Chou, Stella T
Published in Leukemia (01.01.2019)
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Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia
Tasian, Sarah K., Doral, Michelle Y., Borowitz, Michael J., Wood, Brent L., Chen, I-Ming, Harvey, Richard C., Gastier-Foster, Julie M., Willman, Cheryl L., Hunger, Stephen P., Mullighan, Charles G., Loh, Mignon L.
Published in Blood (26.07.2012)
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Nishii, Rina, Baskin-Doerfler, Rebekah, Yang, Wentao, Oak, Ninad, Zhao, Xujie, Yang, Wenjian, Hoshitsuki, Keito, Bloom, Mackenzie, Verbist, Katherine, Burns, Melissa, Li, Zhenhua, Lin, Ting-Nien, Qian, Maoxiang, Moriyama, Takaya, Gastier-Foster, Julie M., Rabin, Karen R., Raetz, Elizabeth, Mullighan, Charles, Pui, Ching-Hon, Yeoh, Allen Eng-Juh, Zhang, Jinghui, Metzger, Monika L., Klco, Jeffery M., Hunger, Stephen P., Newman, Scott, Wu, Gang, Loh, Mignon L., Nichols, Kim E., Yang, Jun J.
Published in Blood (21.01.2021)
Published in Blood (21.01.2021)
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Outcome of Patients Treated for Relapsed or Refractory Acute Lymphoblastic Leukemia: A Therapeutic Advances in Childhood Leukemia Consortium Study
Ko, Richard H, LINGYUN JI, GAYNON, Paul S, LOH, Mignon L, BARNETTE, Phillip, BOSTROM, Bruce, HUTCHINSON, Raymond, RAETZ, Elizabeth, SEIBEL, Nita L, TWIST, Clare J, ECKROTH, Elena, SPOSTO, Richard
Published in Journal of clinical oncology (01.02.2010)
Published in Journal of clinical oncology (01.02.2010)
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