Neutrophil Extracellular Traps Drive Endothelial-to-Mesenchymal Transition
Pieterse, Elmar, Rother, Nils, Garsen, Marjolein, Hofstra, Julia M, Satchell, Simon C, Hoffmann, Markus, Loeven, Markus A, Knaapen, Hanneke K, van der Heijden, Olivier W.H, Berden, Jo H.M, Hilbrands, Luuk B, van der Vlag, Johan
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2017)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2017)
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CD44 is required for the pathogenesis of experimental crescentic glomerulonephritis and collapsing focal segmental glomerulosclerosis
Eymael, Jennifer, Sharma, Shagun, Loeven, Markus A., Wetzels, Jack F., Mooren, Fieke, Florquin, Sandrine, Deegens, Jeroen K., Willemsen, Brigith K., Sharma, Vikram, van Kuppevelt, Toin H., Bakker, Marinka A., Ostendorf, Tammo, Moeller, Marcus J., Dijkman, Henry B., Smeets, Bart, van der Vlag, Johan
Published in Kidney international (01.03.2018)
Published in Kidney international (01.03.2018)
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Blocking of inflammatory heparan sulfate domains by specific antibodies is not protective in experimental glomerulonephritis
van Gemst, Jasper J, Passmann, Nathalie J H G, Rops, Angelique L W M M, van Kuppevelt, Toin H, Berden, Jo H, Loeven, Markus A, Rabelink, Ton J, Smeets, Bart, van der Vlag, Johan
Published in PloS one (23.12.2021)
Published in PloS one (23.12.2021)
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A Novel Choroidal Endothelial Cell Line Has a Decreased Affinity for the Age-Related Macular Degeneration-Associated Complement Factor H Variant 402H
Loeven, Markus A, van Gemst, Jasper J, Schophuizen, Carolien M S, Tilakaratna, Viranga, van den Heuvel, Lambert P, Day, Anthony J, Klevering, B Jeroen, van der Vlag, Johan
Published in Investigative ophthalmology & visual science (01.02.2018)
Published in Investigative ophthalmology & visual science (01.02.2018)
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Selective Binding of Heparin/Heparan Sulfate Oligosaccharides to Factor H and Factor H-Related Proteins: Therapeutic Potential for C3 Glomerulopathies
Loeven, Markus A, Maciej-Hulme, Marissa L, Yanginlar, Cansu, Hubers, Melanie C, Kellenbach, Edwin, de Graaf, Mark, van Kuppevelt, Toin H, Wetzels, Jack, Rabelink, Ton J, Smith, Richard J H, van der Vlag, Johan
Published in Frontiers in immunology (18.08.2021)
Published in Frontiers in immunology (18.08.2021)
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Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis
LWMM Rops, Angelique, Loeven, Markus A., van Gemst, Jasper J., Eversen, Iris, Van Wijk, Xander M., Dijkman, Henry B., van Kuppevelt, Toin H., Berden, Jo H.M., Rabelink, Ton J., Esko, Jeffrey D., van der Vlag, Johan
Published in Kidney international (01.11.2014)
Published in Kidney international (01.11.2014)
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Journal Article
RNA Contaminates Glycosaminoglycans Extracted from Cells and Tissues
van Gemst, Jasper J, Loeven, Markus A, de Graaf, Mark J J, Berden, Jo H M, Rabelink, Ton J, Smit, Cornelis H, van der Vlag, Johan
Published in PloS one (29.11.2016)
Published in PloS one (29.11.2016)
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Inhibition of mTOR delayed but could not prevent experimental collapsing focal segmental glomerulosclerosis
Miesen, Laura, Eymael, Jennifer, Sharma, Shagun, Loeven, Markus A., Willemsen, Brigith, Bakker-van Bebber, Marinka, Mooren, Fieke, Meyer-Schwesinger, Catherine, Dijkman, Henry, Wetzels, Jack F. M., Jansen, Jitske, van der Vlag, Johan, Smeets, Bart
Published in Scientific reports (22.05.2020)
Published in Scientific reports (22.05.2020)
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Mutations in Complement Factor H Impair Alternative Pathway Regulation on Mouse Glomerular Endothelial Cells in Vitro
Loeven, Markus A., Rops, Angelique L., Lehtinen, Markus J., van Kuppevelt, Toin H., Daha, Mohamed R., Smith, Richard J., Bakker, Marinka, Berden, Jo H., Rabelink, Ton J., Jokiranta, T. Sakari, van der Vlag, Johan
Published in The Journal of biological chemistry (04.03.2016)
Published in The Journal of biological chemistry (04.03.2016)
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Panels of chemically-modified heparin polysaccharides and natural heparan sulfate saccharides both exhibit differences in binding to Slit and Robo, as well as variation between protein binding and cellular activity
Ahmed, Yassir A, Yates, Edwin A, Moss, Diana J, Loeven, Markus A, Hussain, Sadaf-Ahmahni, Hohenester, Erhard, Turnbull, Jeremy E, Powell, Andrew K
Published in Molecular bioSystems (01.01.2016)
Published in Molecular bioSystems (01.01.2016)
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Heparan sulfate-modifying enzymes differentially determine complement factor H/factor H-related protein binding to glomerular endothelial cells
Loeven, Markus A., Satchell, Simon C., van Kuppevelt, Toin H., van der Vlag, Johan
Published in Molecular immunology (01.09.2017)
Published in Molecular immunology (01.09.2017)
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Panels of chemically-modified heparin polysaccharides and natural heparan sulfate saccharides both exhibit differences in binding to Slit and Robo, as well as variation between protein binding and cellular activityElectronic supplementary information (ESI) available: NMR chemical shift characterisation of modified heparins, protein sequence alignment methodology and data, protein binding and activity assay dose-response curves. See DOI: 10.1039/c6mb00432f
Ahmed, Yassir A, Yates, Edwin A, Moss, Diana J, Loeven, Markus A, Hussain, Sadaf-Ahmahni, Hohenester, Erhard, Turnbull, Jeremy E, Powell, Andrew K
Year of Publication 20.09.2016
Year of Publication 20.09.2016
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Panels of chemically-modified heparin polysaccharides and natural heparan sulfate saccharides both exhibit differences in binding to Slit and Robo, as well as variation between protein binding and cellular activity† †Electronic supplementary information (ESI) available: NMR chemical shift characterisation of modified heparins, protein sequence alignment methodology and data, protein binding and activity assay dose-response curves. See DOI: 10.1039/c6mb00432f Click here for additional data file
Ahmed, Yassir A., Yates, Edwin A., Moss, Diana J., Loeven, Markus A., Hussain, Sadaf-Ahmahni, Hohenester, Erhard, Turnbull, Jeremy E., Powell, Andrew K.
Published in Molecular bioSystems (04.08.2016)
Published in Molecular bioSystems (04.08.2016)
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