Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia
Kim, Minsoo, Haney, Jillian R., Zhang, Pan, Hernandez, Leanna M., Wang, Lee-kai, Perez-Cano, Laura, Loohuis, Loes M. Olde, de la Torre-Ubieta, Luis, Gandal, Michael J.
Published in Nature neuroscience (01.06.2021)
Published in Nature neuroscience (01.06.2021)
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Journal Article
Structural Brain Alterations in Youth With Psychosis and Bipolar Spectrum Symptoms
Jalbrzikowski, Maria, Freedman, David, Hegarty, Catherine E., Mennigen, Eva, Karlsgodt, Katherine H., Olde Loohuis, Loes M., Ophoff, Roel A., Gur, Raquel E., Bearden, Carrie E.
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01.11.2019)
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01.11.2019)
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Journal Article
Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia
Olde Loohuis, Loes M., Mangul, Serghei, Ori, Anil P. S., Jospin, Guillaume, Koslicki, David, Yang, Harry Taegyun, Wu, Timothy, Boks, Marco P., Lomen-Hoerth, Catherine, Wiedau-Pazos, Martina, Cantor, Rita M., de Vos, Willem M., Kahn, René S., Eskin, Eleazar, Ophoff, Roel A.
Published in Translational psychiatry (10.05.2018)
Published in Translational psychiatry (10.05.2018)
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Journal Article
Polygenic scoring accuracy varies across the genetic ancestry continuum
Ding, Yi, Hou, Kangcheng, Xu, Ziqi, Pimplaskar, Aditya, Petter, Ella, Boulier, Kristin, Privé, Florian, Vilhjálmsson, Bjarni J., Olde Loohuis, Loes M., Pasaniuc, Bogdan
Published in Nature (London) (22.06.2023)
Published in Nature (London) (22.06.2023)
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Journal Article
Genetic and clinical analyses of psychosis spectrum symptoms in a large multiethnic youth cohort reveal significant link with ADHD
Olde Loohuis, Loes M., Mennigen, Eva, Ori, Anil P. S., Perkins, Diana, Robinson, Elise, Addington, Jean, Cadenhead, Kristin S., Cornblatt, Barbara A., Mathalon, Daniel H., McGlashan, Thomas H., Seidman, Larry J., Keshavan, Matcheri S., Stone, William S., Tsuang, Ming T., Walker, Elaine F., Woods, Scott W., Cannon, Tyrone D., Gur, Ruben C., Gur, Raquel E., Bearden, Carrie E., Ophoff, Roel A.
Published in Translational psychiatry (28.01.2021)
Published in Translational psychiatry (28.01.2021)
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Journal Article
Geospatial investigations in Colombia reveal variations in the distribution of mood and psychotic disorders
Song, Janet, Ramírez, Mauricio Castaño, Okano, Justin T., Service, Susan K., de la Hoz, Juan, Díaz-Zuluaga, Ana M., Upegui, Cristian Vargas, Gallago, Cristian, Arias, Alejandro, Sánchez, Alexandra Valderrama, Teshiba, Terri, Sabatti, Chiara, Gur, Ruben C., Bearden, Carrie E., Escobar, Javier I., Reus, Victor I., Jaramillo, Carlos Lopez, Freimer, Nelson B., Olde Loohuis, Loes M., Blower, Sally
Published in Communications medicine (21.02.2024)
Published in Communications medicine (21.02.2024)
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Journal Article
Defining the distance between diseases using SNOMED CT embeddings
Fu, Mingzhou, Yan, Yu, Olde Loohuis, Loes M, Chang, Timothy S
Published in Journal of biomedical informatics (01.03.2023)
Published in Journal of biomedical informatics (01.03.2023)
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Journal Article
Whole blood transcriptome analysis in bipolar disorder reveals strong lithium effect
Krebs, Catharine E., Ori, Anil P.S., Vreeker, Annabel, Wu, Timothy, Cantor, Rita M., Boks, Marco P. M., Kahn, Rene S., Olde Loohuis, Loes M., Ophoff, Roel A.
Published in Psychological medicine (01.11.2020)
Published in Psychological medicine (01.11.2020)
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Journal Article
A Genetic Population Isolate in The Netherlands Showing Extensive Haplotype Sharing and Long Regions of Homozygosity
Somers, Metten, Olde Loohuis, Loes M, Aukes, Maartje F, Pasaniuc, Bogdan, de Visser, Kees C L, Kahn, René S, Sommer, Iris E, Ophoff, Roel A
Published in Genes (04.05.2017)
Published in Genes (04.05.2017)
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Journal Article
State-Dependent Functional Dysconnectivity in Youth With Psychosis Spectrum Symptoms
Mennigen, Eva, Jolles, Dietsje D, Hegarty, Catherine E, Gupta, Mohan, Jalbrzikowski, Maria, Olde Loohuis, Loes M, Ophoff, Roel A, Karlsgodt, Katherine H, Bearden, Carrie E
Published in Schizophrenia bulletin (01.03.2020)
Published in Schizophrenia bulletin (01.03.2020)
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Journal Article
Double hits in schizophrenia
Vorstman, Jacob A S, Olde Loohuis, Loes M, Kahn, René S, Ophoff, Roel A
Published in Human molecular genetics (01.08.2018)
Published in Human molecular genetics (01.08.2018)
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Journal Article
Meta-analysis of epigenetic aging in schizophrenia reveals multifaceted relationships with age, sex, illness duration, and polygenic risk
Ori, Anil P S, Olde Loohuis, Loes M, Guintivano, Jerry, Hannon, Eilis, Dempster, Emma, St Clair, David, Bass, Nick J, McQuillin, Andrew, Mill, Jonathan, Sullivan, Patrick F, Kahn, Rene S, Horvath, Steve, Ophoff, Roel A
Published in Clinical epigenetics (08.04.2024)
Published in Clinical epigenetics (08.04.2024)
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Journal Article
Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates
Sul, Jae Hoon, Service, Susan K., Huang, Alden Y., Ramensky, Vasily, Hwang, Sun-Goo, Teshiba, Terri M., Park, YoungJun, Ori, Anil P. S., Zhang, Zhongyang, Mullins, Niamh, Olde Loohuis, Loes M., Fears, Scott C., Araya, Carmen, Araya, Xinia, Spesny, Mitzi, Bejarano, Julio, Ramirez, Margarita, Castrillón, Gabriel, Gomez-Makhinson, Juliana, Lopez, Maria C., Montoya, Gabriel, Montoya, Claudia P., Aldana, Ileana, Escobar, Javier I., Ospina-Duque, Jorge, Kremeyer, Barbara, Bedoya, Gabriel, Ruiz-Linares, Andres, Cantor, Rita M., Molina, Julio, Coppola, Giovanni, Ophoff, Roel A., Macaya, Gabriel, Lopez-Jaramillo, Carlos, Reus, Victor, Bearden, Carrie E., Sabatti, Chiara, Freimer, Nelson B.
Published in Translational psychiatry (24.02.2020)
Published in Translational psychiatry (24.02.2020)
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Journal Article
Genome-wide burden of deleterious coding variants increased in schizophrenia
Loohuis, Loes M. Olde, Vorstman, Jacob A. S., Ori, Anil P., Staats, Kim A., Wang, Tina, Richards, Alexander L., Leonenko, Ganna, Walters, James T., DeYoung, Joseph, Cantor, Rita M., Ophoff, Roel A.
Published in Nature communications (09.07.2015)
Published in Nature communications (09.07.2015)
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Journal Article
The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma
Loohuis, Loes M, Albersen, Monique, de Jong, Simone, Wu, Timothy, Luykx, Jurjen J, Jans, Judith J M, Verhoeven-Duif, Nanda M, Ophoff, Roel A
Published in Genes (22.12.2018)
Published in Genes (22.12.2018)
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Journal Article
Polygenic Risk Associations with Clinical Characteristics and Recurrence of Dupuytren Disease
Riesmeijer, Sophie A, Nolte, Ilja M, Olde Loohuis, Loes M, Reus, Lianne M, Boltz, Toni, Ng, Michael, Furniss, Dominic, Werker, Paul M N, Ophoff, Roel A
Published in Plastic and reconstructive surgery (1963) (01.03.2024)
Published in Plastic and reconstructive surgery (1963) (01.03.2024)
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Journal Article
Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia
de Vrij, Femke M., Bouwkamp, Christian G., Gunhanlar, Nilhan, Shpak, Guy, Lendemeijer, Bas, Baghdadi, Maarouf, Gopalakrishna, Shreekara, Ghazvini, Mehrnaz, Li, Tracy M., Quadri, Marialuisa, Olgiati, Simone, Breedveld, Guido J., Coesmans, Michiel, Mientjes, Edwin, de Wit, Ton, Verheijen, Frans W., Beverloo, H. Berna, Cohen, Dan, Kok, Rob M., Bakker, P. Roberto, Nijburg, Aviva, Spijker, Annet T., Haffmans, P. M. Judith, Hoencamp, Erik, Bergink, Veerle, Vorstman, Jacob A., Wu, Timothy, Olde Loohuis, Loes M., Amin, Najaf, Langen, Carolyn D., Hofman, Albert, Hoogendijk, Witte J., van Duijn, Cornelia M., Ikram, M. Arfan, Vernooij, Meike W., Tiemeier, Henning, Uitterlinden, André G., Elgersma, Ype, Distel, Ben, Gribnau, Joost, White, Tonya, Bonifati, Vincenzo, Kushner, Steven A.
Published in Molecular psychiatry (01.05.2019)
Published in Molecular psychiatry (01.05.2019)
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Journal Article
Predicting diagnostic conversion from major depressive disorder to bipolar disorder: an EHR based study from Colombia
Service, Susan K, De La Hoz, Juan, Diaz-Zuluaga, Ana M, Arias, Alejandro, Pimplaskar, Aditya, Luu, Chuc, Mena, Laura, Valencia, Johanna, Ramírez, Mauricio Castaño, Bearden, Carrie E, Sabbati, Chiara, Reus, Victor I, López-Jaramillo, Carlos, Freimer, Nelson B, Loohuis, Loes M Olde
Published in medRxiv : the preprint server for health sciences (02.10.2023)
Published in medRxiv : the preprint server for health sciences (02.10.2023)
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Journal Article
Distinguishing different psychiatric disorders using DDx-PRS
Peyrot, Wouter J, Panagiotaropoulou, Georgia, Olde Loohuis, Loes M, Adams, Mark J, Awasthi, Swapnil, Ge, Tian, McIntosh, Andrew M, Mitchell, Brittany L, Mullins, Niamh, O'Connell, Kevin S, Penninx, Brenda W J H, Posthuma, Danielle, Ripke, Stephan, Ruderfer, Douglas M, Uffelmann, Emil, Vilhjalmsson, Bjarni J, Zhu, Zhihong, Smoller, Jordan W, Price, Alkes L
Published in medRxiv : the preprint server for health sciences (04.02.2024)
Published in medRxiv : the preprint server for health sciences (04.02.2024)
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