Nuclear receptor Nur77 and Yin‐Yang 1 synergistically increase mitochondrial abundance and activity in macrophages
Koenis, Duco S., Evers‐van Gogh, Inkie J. A., van Loenen, Pieter B., Zwart, Wilbert, Kalkhoven, Eric, Vries, Carlie J. M.
Published in FEBS letters (01.07.2024)
Published in FEBS letters (01.07.2024)
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Nuclear Receptor Nur77 Controls Cardiac Fibrosis through Distinct Actions on Fibroblasts and Cardiomyocytes
Medzikovic, Lejla, Heese, Hylja, van Loenen, Pieter B, van Roomen, Cindy P A A, Hooijkaas, Ingeborg B, Christoffels, Vincent M, Creemers, Esther E, de Vries, Carlie J M, de Waard, Vivian
Published in International journal of molecular sciences (05.02.2021)
Published in International journal of molecular sciences (05.02.2021)
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Nur77 protects against adverse cardiac remodelling by limiting neuropeptide Y signalling in the sympathoadrenal-cardiac axis
Medzikovic, Lejla, van Roomen, Cindy, Baartscheer, Antonius, van Loenen, Pieter B, de Vos, Judith, Bakker, Erik N T P, Koenis, Duco S, Damanafshan, Amin, Creemers, Esther E, Arkenbout, E Karin, de Vries, Carlie J M, de Waard, Vivian
Published in Cardiovascular research (01.10.2018)
Published in Cardiovascular research (01.10.2018)
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Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1α and affect bone marrow homeostasis in mice and humans
Koenis, Duco S., Medzikovic, Lejla, Vos, Mariska, Beldman, Thijs J., van Loenen, Pieter B., van Tiel, Claudia M., Hamers, Anouk A.J., Otermin Rubio, Iker, de Waard, Vivian, de Vries, Carlie J.M.
Published in The Journal of biological chemistry (28.09.2018)
Published in The Journal of biological chemistry (28.09.2018)
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Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity
Kurakula, Kondababu, Koenis, Duco S, Herzik, Jr, Mark A, Liu, Yanyun, Craft, Jr, John W, van Loenen, Pieter B, Vos, Mariska, Tran, M Khang, Versteeg, Henri H, Goumans, Marie-José T H, Ruf, Wolfram, de Vries, Carlie J M, Şen, Mehmet
Published in Haematologica (Roma) (01.06.2018)
Published in Haematologica (Roma) (01.06.2018)
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Sphingosine‐1‐Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning
Keul, Petra, Borren, Marcel M. G. J., Ghanem, Alexander, Müller, Frank Ulrich, Baartscheer, Antonius, Verkerk, Arie O., Stümpel, Frank, Schulte, Jan Sebastian, Hamdani, Nazha, Linke, Wolfgang A., Loenen, Pieter, Matus, Marek, Schmitz, Wilhelm, Stypmann, Jörg, Tiemann, Klaus, Ravesloot, Jan‐Hindrik, Alewijnse, Astrid E., Hermann, Sven, Spijkers, Léon J. A., Hiller, Karl‐Heinz, Herr, Deron, Heusch, Gerd, Schäfers, Michael, Peters, Stephan L. M., Chun, Jerold, Levkau, Bodo
Published in Journal of the American Heart Association (20.05.2016)
Published in Journal of the American Heart Association (20.05.2016)
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LIM-Only Protein FHL2 Is a Positive Regulator of Liver X Receptors in Smooth Muscle Cells Involved in Lipid Homeostasis
Kurakula, Kondababu, Sommer, Daniela, Sokolovic, Milka, Moerland, Perry D., Scheij, Saskia, van Loenen, Pieter B., Koenis, Duco S., Zelcer, Noam, van Tiel, Claudia M., de Vries, Carlie J. M.
Published in Molecular and cellular biology (01.01.2015)
Published in Molecular and cellular biology (01.01.2015)
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Sphingosine-1-Phosphate Receptor-1 Controls Venous Endothelial Barrier Integrity in Zebrafish
Tobia, Chiara, Chiodelli, Paola, Nicoli, Stefania, Dell’Era, Patrizia, Buraschi, Simone, Mitola, Stefania, Foglia, Efrem, van Loenen, Pieter B, Alewijnse, Astrid E, Presta, Marco
Published in Arteriosclerosis, thrombosis, and vascular biology (01.09.2012)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.09.2012)
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Agonist-dependent effects of mutations in the sphingosine-1-phosphate type 1 receptor
van Loenen, Pieter B., de Graaf, Chris, Verzijl, Dennis, Leurs, Rob, Rognan, Didier, Peters, Stephan L.M., Alewijnse, Astrid E.
Published in European journal of pharmacology (30.09.2011)
Published in European journal of pharmacology (30.09.2011)
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S1P receptor signalling and RGS proteins; expression and function in vascular smooth muscle cells and transfected CHO cells
Hendriks-Balk, Mariëlle C., van Loenen, Pieter B., Hajji, Najat, Michel, Martin C., Peters, Stephan L.M., Alewijnse, Astrid E.
Published in European journal of pharmacology (14.12.2008)
Published in European journal of pharmacology (14.12.2008)
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Sphingosine-1-phosphate regulates RGS2 and RGS16 mRNA expression in vascular smooth muscle cells
Hendriks-Balk, Mariëlle C., Hajji, Najat, van Loenen, Pieter B., Michel, Martin C., Peters, Stephan L.M., Alewijnse, Astrid E.
Published in European journal of pharmacology (15.03.2009)
Published in European journal of pharmacology (15.03.2009)
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Embryonic expression patterns of the Drosophila dystrophin-associated glycoprotein complex orthologs
Dekkers, Linda C., van der Plas, Mariska C., van Loenen, Pieter B., den Dunnen, Johan T., van Ommen, Gert-Jan B., Fradkin, Lee G., Noordermeer, Jasprina N.
Published in Gene Expression Patterns (01.03.2004)
Published in Gene Expression Patterns (01.03.2004)
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Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response through Transcriptional Reprogramming of Mitochondrial Metabolism
Koenis, Duco Steven, Medzikovic, Lejla, van Loenen, Pieter Bas, van Weeghel, Michel, Huveneers, Stephan, Vos, Mariska, Evers-van Gogh, Ingrid Johanna, Van den Bossche, Jan, Speijer, Dave, Kim, Yongsoo, Wessels, Lodewyk, Zelcer, Noam, Zwart, Wilbert, Kalkhoven, Eric, de Vries, Carlie Jacoba
Published in Cell reports (Cambridge) (21.08.2018)
Published in Cell reports (Cambridge) (21.08.2018)
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Controlled large-scale manufacturing of hiPSC-derived cardiomyocytes in stirred-tank bioreactors for high-throughput safety assessment in drug discovery and development
de Korte, Tessa, Veenman, Jessica, Langenberg, Karin, van Loenen, Pieter, Nacken, Peter, Famili, Farbod, Reijerkerk, Arie
Published in Journal of pharmacological and toxicological methods (01.09.2020)
Published in Journal of pharmacological and toxicological methods (01.09.2020)
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High throughput screening in calcium transient assay to assess cardiotoxicity of compounds using hiPSC-derived cardiomyocytes
Famili, Farbod, Lam, Tsang Wai, van Loenen, Pieter, Nacken, Peter, Bras, Maaike, Honarnejad, Saman, Jiang, Yang, Borgdroff, Viola, Bohlen, Heribert, Reijerkerk, Arie, Rutjes, Helma, Braam, Stefan, Luerman, Greg
Published in Journal of pharmacological and toxicological methods (01.09.2019)
Published in Journal of pharmacological and toxicological methods (01.09.2019)
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Journal Article
Sphingosine‐1‐Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca 2+ Sensitivity and Na + /H + Exchange and Mediates Protection by Ischemic Preconditioning
Keul, Petra, van Borren, Marcel M. G. J., Ghanem, Alexander, Müller, Frank Ulrich, Baartscheer, Antonius, Verkerk, Arie O., Stümpel, Frank, Schulte, Jan Sebastian, Hamdani, Nazha, Linke, Wolfgang A., van Loenen, Pieter, Matus, Marek, Schmitz, Wilhelm, Stypmann, Jörg, Tiemann, Klaus, Ravesloot, Jan‐Hindrik, Alewijnse, Astrid E., Hermann, Sven, Spijkers, Léon J. A., Hiller, Karl‐Heinz, Herr, Deron, Heusch, Gerd, Schäfers, Michael, Peters, Stephan L. M., Chun, Jerold, Levkau, Bodo
Published in Journal of the American Heart Association (06.05.2016)
Published in Journal of the American Heart Association (06.05.2016)
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Molecular and Cellular Pharmacology: Sphingosine-1-phosphate regulates RGS2 and RGS16 mRNA expression in vascular smooth muscle cells
Hendriks-Balk, Marielle C, Hajji, Najat, van Loenen, Pieter B, Michel, Martin C, Peters, Stephan L M, Alewijnse, Astrid E
Published in European journal of pharmacology (01.03.2009)
Published in European journal of pharmacology (01.03.2009)
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SIP receptor signalling and RGS proteins; expression and function in vascular smooth muscle cells and transfected CHO cells
HENDRIKS-BALK, Mariëlle C, VAN LOENEN, Pieter B, HAJJI, Najat, MICHEL, Martin C, PETERS, Stephan L. M, ALEWIJNSE, Astrid E
Published in European journal of pharmacology (2008)
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Published in European journal of pharmacology (2008)
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