Nox4 mediates the expression of plasminogen activator inhibitor-1 via p38 MAPK pathway in cultured human endothelial cells
Jaulmes, Amandine, Sansilvestri-Morel, Patricia, Rolland-Valognes, Gaëlle, Bernhardt, Fabienne, Gaertner, Roger, Lockhart, Brian P, Cordi, Alex, Wierzbicki, Michel, Rupin, Alain, Verbeuren, Tony J
Published in Thrombosis research (01.09.2009)
Published in Thrombosis research (01.09.2009)
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S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab
Burbridge, Mike F, Bossard, Céline J, Saunier, Carine, Fejes, Imre, Bruno, Alain, Léonce, Stéphane, Ferry, Gilles, Da Violante, Georges, Bouzom, François, Cattan, Valérie, Jacquet-Bescond, Anne, Comoglio, Paolo M, Lockhart, Brian P, Boutin, Jean A, Cordi, Alex, Ortuno, Jean-Claude, Pierré, Alain, Hickman, John A, Cruzalegui, Francisco H, Depil, Stéphane
Published in Molecular cancer therapeutics (01.09.2013)
Published in Molecular cancer therapeutics (01.09.2013)
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Neuropilin-1 is upregulated in hepatocellular carcinoma and contributes to tumour growth and vascular remodelling
Bergé, Mathieu, Allanic, David, Bonnin, Philippe, de Montrion, Catherine, Richard, Johann, Suc, Michel, Boivin, Jean-François, Contrerès, Jean-Olivier, Lockhart, Brian P, Pocard, Marc, Lévy, Bernard I, Tucker, Gordon C, Tobelem, Gérard, Merkulova-Rainon, Tatyana
Published in Journal of hepatology (01.10.2011)
Published in Journal of hepatology (01.10.2011)
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Genetic deletion of trace amine 1 receptors reveals their role in auto-inhibiting the actions of ecstasy (MDMA)
Di Cara, Benjamin, Maggio, Roberto, Aloisi, Gabriella, Rivet, Jean-Michel, Lundius, Ebba Gregorsson, Yoshitake, Takashi, Svenningsson, Per, Brocco, Mauricette, Gobert, Alain, De Groote, Lotte, Cistarelli, Laetitia, Veiga, Sylvie, De Montrion, Catherine, Rodriguez, Marianne, Galizzi, Jean-Pierre, Lockhart, Brian P, Cogé, Francis, Boutin, Jean A, Vayer, Philippe, Verdouw, P Monika, Groenink, Lucianne, Millan, Mark J
Published in The Journal of neuroscience (23.11.2011)
Published in The Journal of neuroscience (23.11.2011)
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Only a subset of Met-activated pathways are required to sustain oncogene addiction
Bertotti, Andrea, Burbridge, Mike F, Gastaldi, Stefania, Galimi, Francesco, Torti, Davide, Medico, Enzo, Giordano, Silvia, Corso, Simona, Rolland-Valognes, Gaëlle, Lockhart, Brian P, Hickman, John A, Comoglio, Paolo M, Trusolino, Livio
Published in Science signaling (08.12.2009)
Published in Science signaling (08.12.2009)
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Neuroprotective and anti-amnesic potentials of sigma (σ) receptor ligands
Maurice, Tangui, Lockhart, Brian P.
Published in Progress in Neuropsychopharmacology & Biological Psychiatry (1997)
Published in Progress in Neuropsychopharmacology & Biological Psychiatry (1997)
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Abstract 848: Preclinical antitumor activity of S 49076, a novel MET / AXL / FGFR kinase inhibitor and molecular stratification for tumor sensitivity
Burbridge, Mike F., Bossard, Celine, Saunier, Carine, Fejes, Imre, Bruno, Alain, Pierre, Alain, Guigal-Stephan, Nolwen, Rodriguez, Marianne, Galizzi, Jean-Pierre, Lockhart, Brian P., Jacquet-Bescond, Anne, Ortuno, Jean-Claude, Cruzalegui, Francisco H., Depil, Stephane
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Abstract A240: Preclinical molecular stratification of human tumors sensitive or resistant to S 49076, a novel MET/FGFR/AXL kinase inhibitor
Burbridge, Mike F., Bossard, Celine, Saunier, Carine, Bourrier, Chantal, Guigal-Stephan, Nolwen, Rodriguez, Marianne, Galizzi, Jean-Pierre, Jacquet-Bescond, Anne, Lockhart, Brian P., Ortuno, Jean-Claude, Cruzalegui, Francisco, Depil, Stephane
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Journal Article
Abstract A238: S 49076, a novel, potent, MET/FGFR/AXL kinase inhibitor with wide antitumor activity
Burbridge, Mike F., Saunier, Carine, Bossard, Celine, Bruno, Alain, Fejes, Imre, Rolland-Valognes, Gaelle, Pierre, Alain, Lopez-Busto, Natividad, Jacquet-Bescond, Anne, Lockhart, Brian P., Cordi, Alex, Hickman, John A., Trusolino, Livio, Comoglio, Paolo M., Ortuno, Jean-Claude, Cruzalegui, Francisco, Depil, Stephane
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Journal Article
Only a subset of Met-activated pathways are required to sustain oncogene addiction
Bertotti, Andrea, Burbridge, Mike F, Gastaldi, Stefania, Galimi, Francesco, Torti, Davide, Medico, Enzo, Giordano, Silvia, Corso, Simona, Rolland-Valognes, Gaëlle, Lockhart, Brian P, Hickman, John A, Comoglio, Paolo M, Trusolino, Livio
Published in Science signaling (2009)
Published in Science signaling (2009)
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Journal Article
P1-415 S18986, enhances BDNF expression in rat primary neuronal cultures
Lockhart, Brian P., Rodriguez, Marianne, Catesson, Sandra, Mourlevat, Sophie, Peron, Philippe, Villain, Nadège, Danober, Laurence, Boutin, Jean A., Galizzi, Jean-Pierre, Lestage, Pierre J.
Published in Neurobiology of aging (01.07.2004)
Published in Neurobiology of aging (01.07.2004)
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Reversion of β 25–35-amyloid peptide-induced amnesia by NMDA receptor-associated glycine site agonists
Maurice, Tangui, Lockhart, Brian P., Su, Tsung-Ping, Privat, Alain
Published in Brain research (26.08.1996)
Published in Brain research (26.08.1996)
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The epidermolytic (exfoliative) toxins of Staphylococcus aureus
Bailey, C J, Lockhart, B P, Redpath, M B, Smith, T P
Published in Medical microbiology and immunology (01.08.1995)
Published in Medical microbiology and immunology (01.08.1995)
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