Safety and activity of alisertib, an investigational aurora kinase A inhibitor, in patients with breast cancer, small-cell lung cancer, non-small-cell lung cancer, head and neck squamous-cell carcinoma, and gastro-oesophageal adenocarcinoma: a five-arm phase 2 study
Melichar, Bohuslav, Prof, Adenis, Antoine, Prof, Lockhart, A Craig, MD, Bennouna, Jaafar, Prof, Dees, E Claire, Prof, Kayaleh, Omar, MD, Obermannova, Radka, MD, DeMichele, Angela, MD, Zatloukal, Petr, Prof, Zhang, Bin, DSc, Ullmann, Claudio Dansky, MD, Schusterbauer, Claudia, MD
Published in The lancet oncology (01.04.2015)
Published in The lancet oncology (01.04.2015)
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Vemurafenib for BRAF V600-Mutant Erdheim-Chester Disease and Langerhans Cell Histiocytosis: Analysis of Data From the Histology-Independent, Phase 2, Open-label VE-BASKET Study
Diamond, Eli L, Subbiah, Vivek, Lockhart, A Craig, Blay, Jean-Yves, Puzanov, Igor, Chau, Ian, Raje, Noopur S, Wolf, Jurgen, Erinjeri, Joseph P, Torrisi, Jean, Lacouture, Mario, Elez, Elena, Martínez-Valle, Ferran, Durham, Benjamin, Arcila, Maria E, Ulaner, Gary, Abdel-Wahab, Omar, Pitcher, Bethany, Makrutzki, Martina, Riehl, Todd, Baselga, José, Hyman, David M
Published in JAMA oncology (01.03.2018)
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Efficacy and Safety of Pembrolizumab for Heavily Pretreated Patients With Advanced, Metastatic Adenocarcinoma or Squamous Cell Carcinoma of the Esophagus: The Phase 2 KEYNOTE-180 Study
Shah, Manish A, Kojima, Takashi, Hochhauser, Daniel, Enzinger, Peter, Raimbourg, Judith, Hollebecque, Antoine, Lordick, Florian, Kim, Sung-Bae, Tajika, Masahiro, Kim, Heung Tae, Lockhart, A Craig, Arkenau, Hendrik-Tobias, El-Hajbi, Farid, Gupta, Mukul, Pfeiffer, Per, Liu, Qi, Lunceford, Jared, Kang, S Peter, Bhagia, Pooja, Kato, Ken
Published in JAMA oncology (01.04.2019)
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Molecular Characterization of KRAS Wild-type Tumors in Patients with Pancreatic Adenocarcinoma
Philip, Philip A, Azar, Ibrahim, Xiu, Joanne, Hall, Michael J, Hendifar, Andrew Eugene, Lou, Emil, Hwang, Jimmy J, Gong, Jun, Feldman, Rebecca, Ellis, Michelle, Stafford, Phil, Spetzler, David, Khushman, Moh'd M, Sohal, Davendra, Lockhart, A Craig, Weinberg, Benjamin A, El-Deiry, Wafik S, Marshall, John, Shields, Anthony F, Korn, W Michael
Published in Clinical cancer research (13.06.2022)
Published in Clinical cancer research (13.06.2022)
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The preclinical discovery and development of zolbetuximab for the treatment of gastric cancer
Zeng, Yongji, Lockhart, A Craig, Jin, Ramon U
Published in Expert opinion on drug discovery (02.08.2024)
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Large-scale analysis of KMT2 mutations defines a distinctive molecular subset with treatment implication in gastric cancer
Wang, Jingyuan, Xiu, Joanne, Baca, Yasmine, Battaglin, Francesca, Arai, Hiroyuki, Kawanishi, Natsuko, Soni, Shivani, Zhang, Wu, Millstein, Joshua, Salhia, Bodour, Goldberg, Richard M., Philip, Philip A., Seeber, Andreas, Hwang, Jimmy J., Shields, Anthony F., Marshall, John L., Astsaturov, Igor, Craig Lockhart, A., Gatalica, Zoran, Michael Korn, W., Lenz, Heinz-Josef
Published in Oncogene (29.07.2021)
Published in Oncogene (29.07.2021)
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Effects of rifampin, itraconazole and esomeprazole on the pharmacokinetics of alisertib, an investigational aurora a kinase inhibitor in patients with advanced malignancies
Zhou, Xiaofei, Pant, Shubham, Nemunaitis, John, Craig Lockhart, A., Falchook, Gerald, Bauer, Todd M., Patel, Manish, Sarantopoulos, John, Bargfrede, Michael, Muehler, Andreas, Rangachari, Lakshmi, Zhang, Bin, Venkatakrishnan, Karthik
Published in Investigational new drugs (01.04.2018)
Published in Investigational new drugs (01.04.2018)
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Vorolanib (X-82), an oral anti-VEGFR/PDGFR/CSF1R tyrosine kinase inhibitor, with everolimus in solid tumors: results of a phase I study
Pedersen, Katrina S., Grierson, Patrick M., Picus, Joel, Lockhart, A. Craig, Roth, Bruce J., Liu, Jingxia, Morton, Ashley, Chan, Emily, Huffman, Jesse, Liang, Chris, Wang-Gillam, Andrea, Tan, Benjamin
Published in Investigational new drugs (01.10.2021)
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Margetuximab plus pembrolizumab in patients with previously treated, HER2-positive gastro-oesophageal adenocarcinoma (CP-MGAH22–05): a single-arm, phase 1b–2 trial
Catenacci, Daniel V T, Kang, Yoon-Koo, Park, Haeseong, Uronis, Hope E, Lee, Keun-Wook, Ng, Matthew C H, Enzinger, Peter C, Park, Se Hoon, Gold, Philip J, Lacy, Jill, Hochster, Howard S, Oh, Sang Cheul, Kim, Yeul Hong, Marrone, Kristen A, Kelly, Ronan J, Juergens, Rosalyn A, Kim, Jong Gwang, Bendell, Johanna C, Alcindor, Thierry, Sym, Sun Jin, Song, Eun-Kee, Chee, Cheng Ean, Chao, Yee, Kim, Sunnie, Lockhart, A Craig, Knutson, Keith L, Yen, Jennifer, Franovic, Aleksandra, Nordstrom, Jeffrey L, Li, Daner, Wigginton, Jon, Davidson-Moncada, Jan K, Rosales, Minori Koshiji, Bang, Yung-Jue
Published in The lancet oncology (01.08.2020)
Published in The lancet oncology (01.08.2020)
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Adjuvant chemotherapy for patients with pathologic node-positive esophageal cancer after induction chemotherapy is associated with improved survival
Samson, Pamela, Puri, Varun, Lockhart, A. Craig, Robinson, Clifford, Broderick, Stephen, Patterson, G. Alexander, Meyers, Bryan, Crabtree, Traves
Published in The Journal of thoracic and cardiovascular surgery (01.10.2018)
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Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids
NAGATHIHALLI, Nagaraj S, BEESETTY, Yugandhar, WOOIN LEE, WASHINGTON, M. Kay, XI CHEN, LOCKHART, A. Craig, MERCHANT, Nipun B
Published in Cancer research (Chicago, Ill.) (01.04.2014)
Published in Cancer research (Chicago, Ill.) (01.04.2014)
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A phase I trial of temsirolimus and erlotinib in patients with refractory solid tumors
Park, Haeseong, Williams, Kerry, Trikalinos, Nikolaos A., Larson, Sarah, Tan, Benjamin, Waqar, Saiama, Suresh, Rama, Morgensztern, Daniel, Van Tine, Brian A., Govindan, Ramaswamy, Luo, Jingqin, Lockhart, A. Craig, Wang-Gillam, Andrea
Published in Cancer chemotherapy and pharmacology (01.03.2021)
Published in Cancer chemotherapy and pharmacology (01.03.2021)
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Neoadjuvant Chemotherapy versus Chemoradiation Prior to Esophagectomy: Impact on Rate of Complete Pathologic Response and Survival in Esophageal Cancer Patients
Samson, Pamela, Robinson, Clifford, Bradley, Jeffrey, Lockhart, A. Craig, Puri, Varun, Broderick, Stephen, Kreisel, Daniel, Krupnick, A. Sasha, Patterson, G. Alexander, Meyers, Bryan, Crabtree, Traves
Published in Journal of thoracic oncology (01.12.2016)
Published in Journal of thoracic oncology (01.12.2016)
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Phase I Study of Intravenous Vascular Endothelial Growth Factor Trap, Aflibercept, in Patients With Advanced Solid Tumors
LOCKHART, A. Craig, ROTHENBERG, Mace L, GULTEKIN, David H, KOUTCHER, Jason A, DONNELLY, Edwin F, ANDAL, Ric, DANCY, Isabelle, SPRIGGS, David R, TEW, William P, DUPONT, Jakob, COOPER, Wendy, CHEVALIER, Paul, STERNAS, Lars, BUZENET, Giliane, KOEHLER, Elizabeth, SOSMAN, Jeffrey A, SCHWARTZ, Lawrence H
Published in Journal of clinical oncology (10.01.2010)
Published in Journal of clinical oncology (10.01.2010)
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Safety and preliminary evidence of biologic efficacy of a mammaglobin-a DNA vaccine in patients with stable metastatic breast cancer
Tiriveedhi, Venkataswarup, Tucker, Natalia, Herndon, John, Li, Lijin, Sturmoski, Mark, Ellis, Matthew, Ma, Cynthia, Naughton, Michael, Lockhart, A Craig, Gao, Feng, Fleming, Timothy, Goedegebuure, Peter, Mohanakumar, Thalachallour, Gillanders, William E
Published in Clinical cancer research (01.12.2014)
Published in Clinical cancer research (01.12.2014)
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PIB is a non-specific imaging marker of amyloid-beta (Aβ) peptide-related cerebral amyloidosis
Lockhart, A., Lamb, J.R., Osredkar, T., Sue, L.I., Joyce, J.N., Ye, L., Libri, V., Leppert, D., Beach, T.G.
Published in Brain (London, England : 1878) (01.10.2007)
Published in Brain (London, England : 1878) (01.10.2007)
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