Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions
Burr, Stephen P., Costa, Ana S.H., Grice, Guinevere L., Timms, Richard T., Lobb, Ian T., Freisinger, Peter, Dodd, Roger B., Dougan, Gordon, Lehner, Paul J., Frezza, Christian, Nathan, James A.
Published in Cell metabolism (08.11.2016)
Published in Cell metabolism (08.11.2016)
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The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes
Ortmann, Brian M, Burrows, Natalie, Lobb, Ian T, Arnaiz, Esther, Wit, Niek, Bailey, Peter S J, Jordon, Louise H, Lombardi, Olivia, Peñalver, Ana, McCaffrey, James, Seear, Rachel, Mole, David R, Ratcliffe, Peter J, Maxwell, Patrick H, Nathan, James A
Published in Nature genetics (01.07.2021)
Published in Nature genetics (01.07.2021)
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MARCH6 and TRC8 facilitate the quality control of cytosolic and tail‐anchored proteins
Stefanovic‐Barrett, Sandra, Dickson, Anna S, Burr, Stephen P, Williamson, James C, Lobb, Ian T, Boomen, Dick JH, Lehner, Paul J, Nathan, James A
Published in EMBO reports (01.05.2018)
Published in EMBO reports (01.05.2018)
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USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF
Jurisic, Anamarija, Sung, Pei‐Ju, Wappett, Mark, Daubriac, Julien, Lobb, Ian T., Kung, Wei‐Wei, Crawford, Nyree, Page, Natalie, Cassidy, Eamon, Feutren‐Burton, Stephanie, Rountree, J. S. Shane, Helm, Matthew D., O'Dowd, Colin R., Kennedy, Richard D., Gavory, Gerald, Cranston, Aaron N., Longley, Daniel B., Jacq, Xavier, Harrison, Timothy
Published in Clinical and translational medicine (01.04.2024)
Published in Clinical and translational medicine (01.04.2024)
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Identification of a novel TIF-IA-NF-κB nucleolar stress response pathway
Chen, Jingyu, Lobb, Ian T, Morin, Pierre, Novo, Sonia M, Simpson, James, Kennerknecht, Kathrin, von Kriegsheim, Alex, Batchelor, Emily E, Oakley, Fiona, Stark, Lesley A
Published in Nucleic acids research (06.07.2018)
Published in Nucleic acids research (06.07.2018)
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A Role for the Autophagic Receptor, SQSTM1/p62, in Trafficking NF-κB/RelA to Nucleolar Aggresomes
Lobb, Ian T, Morin, Pierre, Martin, Kirsty, Thoms, Hazel C, Wills, Jimi C, Lleshi, Xhordi, Olsen, Karl C F, Duncan, Rory R, Stark, Lesley A
Published in Molecular cancer research (01.02.2021)
Published in Molecular cancer research (01.02.2021)
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Abstract 6057: Discovery of a novel function for USP7 inhibitors: Reprogramming the tumor microenvironment
Jacq, Xavier, Jurisic, Anamarija, Daubriac, Julien, Lobb, Ian T., Wappett, Mark, Cranston, Aaron, Sung, Peggy, Gavory, Gerald, O'Dowd, Colin, Harisson, Tim
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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