Proteases in cancer drug delivery
Vandooren, Jennifer, Opdenakker, Ghislain, Loadman, Paul M., Edwards, Dylan R.
Published in Advanced drug delivery reviews (01.02.2016)
Published in Advanced drug delivery reviews (01.02.2016)
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Journal Article
A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota
Watson, Henry, Mitra, Suparna, Croden, Fiona C, Taylor, Morag, Wood, Henry M, Perry, Sarah L, Spencer, Jade A, Quirke, Phil, Toogood, Giles J, Lawton, Clare L, Dye, Louise, Loadman, Paul M, Hull, Mark A
Published in Gut (01.11.2018)
Published in Gut (01.11.2018)
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Journal Article
How can the potential of the duocarmycins be unlocked for cancer therapy?
Jukes, Zoë, Morais, Goreti Ribeiro, Loadman, Paul M., Pors, Klaus
Published in Drug discovery today (01.02.2021)
Published in Drug discovery today (01.02.2021)
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Journal Article
Progress towards a clinically-successful ATR inhibitor for cancer therapy
Barnieh, Francis M., Loadman, Paul M., Falconer, Robert A.
Published in Current research in pharmacology and drug discovery (01.01.2021)
Published in Current research in pharmacology and drug discovery (01.01.2021)
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Journal Article
Precision pharmacology: Mass spectrometry imaging and pharmacokinetic drug resistance
Jove, Maria, Spencer, Jade, Clench, Malcolm, Loadman, Paul M., Twelves, Chris
Published in Critical reviews in oncology/hematology (01.09.2019)
Published in Critical reviews in oncology/hematology (01.09.2019)
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Journal Article
Eicosapentaenoic acid and aspirin, alone and in combination, for the prevention of colorectal adenomas (seAFOod Polyp Prevention trial): a multicentre, randomised, double-blind, placebo-controlled, 2 × 2 factorial trial
Hull, Mark A, Sprange, Kirsty, Hepburn, Trish, Tan, Wei, Shafayat, Aisha, Rees, Colin J, Clifford, Gayle, Logan, Richard F, Loadman, Paul M, Williams, Elizabeth A, Whitham, Diane, Montgomery, Alan A
Published in The Lancet (British edition) (15.12.2018)
Published in The Lancet (British edition) (15.12.2018)
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Journal Article
Anticolorectal cancer activity of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid
Cockbain, Andrew J, Volpato, Milene, Race, Amanda D, Munarini, Alessandra, Fazio, Chiara, Belluzzi, Andrea, Loadman, Paul M, Toogood, Giles J, Hull, Mark A
Published in Gut (01.11.2014)
Published in Gut (01.11.2014)
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Journal Article
FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms
Tomlinson, Darren C, Baxter, Euan W, Loadman, Paul M, Hull, Mark A, Knowles, Margaret A
Published in PloS one (12.06.2012)
Published in PloS one (12.06.2012)
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Journal Article
Cytochrome P450 Binding and Bioactivation of Tumor-Targeted Duocarmycin Agents
Bart, Aaron G, Morais, Goreti, Vangala, Venu R, Loadman, Paul M, Pors, Klaus, Scott, Emily E
Published in Drug metabolism and disposition (01.01.2022)
Published in Drug metabolism and disposition (01.01.2022)
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Journal Article
Recent advances in the analysis of polysialic acid from complex biological systems
Guo, Xiaoxiao, Elkashef, Sara M., Loadman, Paul M., Patterson, Laurence H., Falconer, Robert A.
Published in Carbohydrate polymers (15.11.2019)
Published in Carbohydrate polymers (15.11.2019)
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Journal Article
Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy
Ansari, Celina, Tikhomirov, Grigory A., Hong, Su Hyun, Falconer, Robert A., Loadman, Paul M., Gill, Jason H., Castaneda, Rosalinda, Hazard, Florette K., Tong, Ling, Lenkov, Olga D., Felsher, Dean W., Rao, Jianghong, Daldrup-Link, Heike E.
Published in Small (Weinheim an der Bergstrasse, Germany) (01.02.2014)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.02.2014)
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Journal Article
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs
Eschweiler, Simon, Ramírez-Suástegui, Ciro, Li, Yingcong, King, Emma, Chudley, Lindsey, Thomas, Jaya, Wood, Oliver, von Witzleben, Adrian, Jeffrey, Danielle, McCann, Katy, Simon, Hayley, Mondal, Monalisa, Wang, Alice, Dicker, Martina, Lopez-Guadamillas, Elena, Chou, Ting-Fang, Dobbs, Nicola A., Essame, Louisa, Acton, Gary, Kelly, Fiona, Halbert, Gavin, Sacco, Joseph J., Schache, Andrew Graeme, Shaw, Richard, McCaul, James Anthony, Paterson, Claire, Davies, Joseph H., Brennan, Peter A., Singh, Rabindra P., Loadman, Paul M., Wilson, William, Hackshaw, Allan, Seumois, Gregory, Okkenhaug, Klaus, Thomas, Gareth J., Jones, Terry M., Ay, Ferhat, Friberg, Greg, Kronenberg, Mitchell, Vanhaesebroeck, Bart, Vijayanand, Pandurangan, Ottensmeier, Christian H.
Published in Nature (London) (26.05.2022)
Published in Nature (London) (26.05.2022)
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Journal Article
Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment
Elkashef, Sara M., Allison, Simon J., Sadiq, Maria, Basheer, Haneen A., Ribeiro Morais, Goreti, Loadman, Paul M., Pors, Klaus, Falconer, Robert A.
Published in Scientific reports (09.09.2016)
Published in Scientific reports (09.09.2016)
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Journal Article
The effect of aspirin and eicosapentaenoic acid on urinary biomarkers of prostaglandin E2 synthesis and platelet activation in participants of the seAFOod polyp prevention trial
Sun, Ge, Fuller, Harriett, Fenton, Hayley, Race, Amanda D, Downing, Amy, Williams, Elizabeth A, Rees, Colin J, Brown, Louise C, Loadman, Paul M, Hull, Mark A
Published in International journal of cancer (01.03.2024)
Published in International journal of cancer (01.03.2024)
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Journal Article
The effect of aspirin and eicosapentaenoic acid on urinary biomarkers of prostaglandin E 2 synthesis and platelet activation in participants of the seAFOod polyp prevention trial
Sun, Ge, Fuller, Harriett, Fenton, Hayley, Race, Amanda D, Downing, Amy, Williams, Elizabeth A, Rees, Colin J, Brown, Louise C, Loadman, Paul M, Hull, Mark A
Published in International journal of cancer (01.03.2024)
Published in International journal of cancer (01.03.2024)
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Journal Article
Colorectal polyp outcomes after participation in the seAFOod polyp prevention trial: Evidence of rebound elevated colorectal polyp risk after short‐term aspirin use
Downing, Amy, Fenton, Hayley, Nickerson, Claire, Loadman, Paul M., Williams, Elizabeth A., Rees, Colin J., Brown, Louise C., Morris, Eva J. A., Hull, Mark A.
Published in Alimentary pharmacology & therapeutics (01.09.2023)
Published in Alimentary pharmacology & therapeutics (01.09.2023)
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Journal Article
Eicosapentaenoic acid free fatty acid prevents and suppresses colonic neoplasia in colitis‐associated colorectal cancer acting on Notch signaling and gut microbiota
Piazzi, Giulia, D'Argenio, Giuseppe, Prossomariti, Anna, Lembo, Vincenzo, Mazzone, Giovanna, Candela, Marco, Biagi, Elena, Brigidi, Patrizia, Vitaglione, Paola, Fogliano, Vincenzo, D'Angelo, Leonarda, Fazio, Chiara, Munarini, Alessandra, Belluzzi, Andrea, Ceccarelli, Claudio, Chieco, Pasquale, Balbi, Tiziana, Loadman, Paul M., Hull, Mark A., Romano, Marco, Bazzoli, Franco, Ricciardiello, Luigi
Published in International journal of cancer (01.11.2014)
Published in International journal of cancer (01.11.2014)
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Journal Article