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Progress towards a clinically-successful ATR inhibitor for cancer therapy
Barnieh, Francis M., Loadman, Paul M., Falconer, Robert A.
Published in Current research in pharmacology and drug discovery (01.01.2021)
Published in Current research in pharmacology and drug discovery (01.01.2021)
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Anticolorectal cancer activity of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid
Cockbain, Andrew J, Volpato, Milene, Race, Amanda D, Munarini, Alessandra, Fazio, Chiara, Belluzzi, Andrea, Loadman, Paul M, Toogood, Giles J, Hull, Mark A
Published in Gut (01.11.2014)
Published in Gut (01.11.2014)
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Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy
Ansari, Celina, Tikhomirov, Grigory A., Hong, Su Hyun, Falconer, Robert A., Loadman, Paul M., Gill, Jason H., Castaneda, Rosalinda, Hazard, Florette K., Tong, Ling, Lenkov, Olga D., Felsher, Dean W., Rao, Jianghong, Daldrup-Link, Heike E.
Published in Small (Weinheim an der Bergstrasse, Germany) (01.02.2014)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.02.2014)
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Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment
Elkashef, Sara M., Allison, Simon J., Sadiq, Maria, Basheer, Haneen A., Ribeiro Morais, Goreti, Loadman, Paul M., Pors, Klaus, Falconer, Robert A.
Published in Scientific reports (09.09.2016)
Published in Scientific reports (09.09.2016)
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Eicosapentaenoic acid free fatty acid prevents and suppresses colonic neoplasia in colitis‐associated colorectal cancer acting on Notch signaling and gut microbiota
Piazzi, Giulia, D'Argenio, Giuseppe, Prossomariti, Anna, Lembo, Vincenzo, Mazzone, Giovanna, Candela, Marco, Biagi, Elena, Brigidi, Patrizia, Vitaglione, Paola, Fogliano, Vincenzo, D'Angelo, Leonarda, Fazio, Chiara, Munarini, Alessandra, Belluzzi, Andrea, Ceccarelli, Claudio, Chieco, Pasquale, Balbi, Tiziana, Loadman, Paul M., Hull, Mark A., Romano, Marco, Bazzoli, Franco, Ricciardiello, Luigi
Published in International journal of cancer (01.11.2014)
Published in International journal of cancer (01.11.2014)
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Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer
Presa, Daniela, Khurram, Syed A., Zubir, Amir Z. A., Smarakan, Sneha, Cooper, Patricia A., Morais, Goreti R., Sadiq, Maria, Sutherland, Mark, Loadman, Paul M., McCaul, James, Shnyder, Steven D., Patterson, Laurence H., Pors, Klaus
Published in Scientific reports (23.09.2021)
Published in Scientific reports (23.09.2021)
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FGFR1-Induced Epithelial to Mesenchymal Transition through MAPK/PLCγ/COX-2-Mediated Mechanisms
Tomlinson, Darren C., Baxter, Euan W., Loadman, Paul M., Hull, Mark A., Knowles, Margaret A.
Published in PloS one (12.06.2012)
Published in PloS one (12.06.2012)
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Targeted microbubbles carrying lipid-oil-nanodroplets for ultrasound-triggered delivery of the hydrophobic drug, combretastatin A4
Charalambous, Antonia, Mico, Victoria, McVeigh, Laura E., Marston, Gemma, Ingram, Nicola, Volpato, Milène, Peyman, Sally A., McLaughlan, James R., Wierzbicki, Antonia, Loadman, Paul M., Bushby, Richard J., Markham, Alexander F., Evans, Stephen D., Coletta, P. Louise
Published in Nanomedicine (01.08.2021)
Published in Nanomedicine (01.08.2021)
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Maleimide–Thiol Linkages Alter the Biodistribution of SN38 Therapeutic Microbubbles Compared to Biotin–Avidin While Preserving Parity in Tumoral Drug Delivery
Ingram, Nicola, Abou-Saleh, Radwa H., Race, Amanda D., Loadman, Paul M., Bushby, Richard J., Evans, Stephen D., Coletta, P. Louise
Published in Pharmaceutics (01.03.2024)
Published in Pharmaceutics (01.03.2024)
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Randomised, placebo-controlled, phase 3 trial of the effect of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) on colorectal cancer recurrence and survival after surgery for resectable liver metastases: EPA for Metastasis Trial 2 (EMT2) study protocol
Hull, Mark A, Ow, Pei Loo, Ruddock, Sharon, Brend, Tim, Smith, Alexandra F, Marshall, Helen, Song, Mingyang, Chan, Andrew T, Garrett, Wendy S, Yilmaz, Omer, Drew, David A, Collinson, Fiona, Cockbain, Andrew J, Jones, Robert, Loadman, Paul M, Hall, Peter S, Moriarty, Catherine, Cairns, David A, Toogood, Giles J
Published in BMJ open (29.11.2023)
Published in BMJ open (29.11.2023)
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Pharmacological Inhibition of polysialyltransferase ST8SiaII Modulates Tumour Cell Migration
Al-Saraireh, Yousef M. J., Sutherland, Mark, Springett, Bradley R., Freiberger, Friedrich, Ribeiro Morais, Goreti, Loadman, Paul M., Errington, Rachel J., Smith, Paul J., Fukuda, Minoru, Gerardy-Schahn, Rita, Patterson, Laurence H., Shnyder, Steven D., Falconer, Robert A.
Published in PloS one (09.08.2013)
Published in PloS one (09.08.2013)
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Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin‐fixed paraffin‐embedded adenocarcinoma tissue sections
Djidja, Marie‐Claude, Francese, Simona, Loadman, Paul M., Sutton, Chris W., Scriven, Peter, Claude, Emmanuelle, Snel, Marten F., Franck, Julien, Salzet, Michel, Clench, Malcolm R.
Published in Proteomics (Weinheim) (01.05.2009)
Published in Proteomics (Weinheim) (01.05.2009)
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A Single Short ‘Tone Burst’ Results in Optimal Drug Delivery to Tumours Using Ultrasound-Triggered Therapeutic Microbubbles
Ingram, Nicola, McVeigh, Laura E., Abou-Saleh, Radwa H., Batchelor, Damien V. B., Loadman, Paul M., McLaughlan, James R., Markham, Alexander F., Evans, Stephen D., Coletta, P. Louise
Published in Pharmaceutics (11.03.2022)
Published in Pharmaceutics (11.03.2022)
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Hypoxia-Selective Targeting by the Bioreductive Prodrug AQ4N in Patients with Solid Tumors: Results of a Phase I Study
Albertella, Mark R., Loadman, Paul M., Jones, Philip H., Phillips, Roger M., Rampling, Roy, Burnet, Neil, Alcock, Chris, Anthoney, Alan, Vjaters, Egils, Dunk, Chris R., Harris, Peter A., Wong, Alvin, Lalani, Alshad S., Twelves, Chris J.
Published in Clinical cancer research (15.02.2008)
Published in Clinical cancer research (15.02.2008)
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Proteases in cancer drug delivery
Vandooren, Jennifer, Opdenakker, Ghislain, Loadman, Paul M., Edwards, Dylan R.
Published in Advanced drug delivery reviews (01.02.2016)
Published in Advanced drug delivery reviews (01.02.2016)
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A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota
Watson, Henry, Mitra, Suparna, Croden, Fiona C, Taylor, Morag, Wood, Henry M, Perry, Sarah L, Spencer, Jade A, Quirke, Phil, Toogood, Giles J, Lawton, Clare L, Dye, Louise, Loadman, Paul M, Hull, Mark A
Published in Gut (01.11.2018)
Published in Gut (01.11.2018)
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