Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing
Lo Sardo, Valentina, Chubukov, Pavel, Ferguson, William, Kumar, Aditya, Teng, Evan L., Duran, Michael, Zhang, Lei, Cost, Gregory, Engler, Adam J., Urnov, Fyodor, Topol, Eric J., Torkamani, Ali, Baldwin, Kristin K.
Published in Cell (13.12.2018)
Published in Cell (13.12.2018)
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Journal Article
Selective conversion of fibroblasts into peripheral sensory neurons
Blanchard, Joel W, Eade, Kevin T, Szűcs, Attila, Lo Sardo, Valentina, Tsunemoto, Rachel K, Williams, Daniel, Sanna, Pietro Paolo, Baldwin, Kristin K
Published in Nature neuroscience (01.01.2015)
Published in Nature neuroscience (01.01.2015)
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Journal Article
An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin
Lo Sardo, Valentina, Zuccato, Chiara, Gaudenzi, Germano, Vitali, Barbara, Ramos, Catarina, Tartari, Marzia, Myre, Michael A, Walker, James A, Pistocchi, Anna, Conti, Luciano, Valenza, Marta, Drung, Binia, Schmidt, Boris, Gusella, James, Zeitlin, Scott, Cotelli, Franco, Cattaneo, Elena
Published in Nature neuroscience (01.05.2012)
Published in Nature neuroscience (01.05.2012)
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Journal Article
Phylogenetic Comparison of Huntingtin Homologues Reveals the Appearance of a Primitive polyQ in Sea Urchin
Tartari, Marzia, Gissi, Carmela, Lo Sardo, Valentina, Zuccato, Chiara, Picardi, Ernesto, Pesole, Graziano, Cattaneo, Elena
Published in Molecular biology and evolution (01.02.2008)
Published in Molecular biology and evolution (01.02.2008)
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Journal Article
Mechanical activation of noncoding-RNA-mediated regulation of disease-associated phenotypes in human cardiomyocytes
Kumar, Aditya, Thomas, Stephanie K, Wong, Kirsten C, Lo Sardo, Valentina, Cheah, Daniel S, Hou, Yang-Hsun, Placone, Jesse K, Tenerelli, Kevin P, Ferguson, William C, Torkamani, Ali, Topol, Eric J, Baldwin, Kristin K, Engler, Adam J
Published in Nature biomedical engineering (01.02.2019)
Published in Nature biomedical engineering (01.02.2019)
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Journal Article
High shear stress enhances endothelial permeability in the presence of the risk haplotype at 9p21.3
Teng, Evan L., Masutani, Evan M., Yeoman, Benjamin, Fung, Jessica, Lian, Rachel, Ngo, Brenda, Kumar, Aditya, Placone, Jesse K., Lo Sardo, Valentina, Engler, Adam J.
Published in APL bioengineering (01.09.2021)
Published in APL bioengineering (01.09.2021)
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Journal Article
Influence of donor age on induced pluripotent stem cells
Lo Sardo, Valentina, Ferguson, William, Erikson, Galina A, Topol, Eric J, Baldwin, Kristin K, Torkamani, Ali
Published in Nature biotechnology (01.01.2017)
Published in Nature biotechnology (01.01.2017)
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The effect of aging on human induced pluripotent stem cells
Sardo, Valentina Lo, Ferguson, William, Erikson, Galina A., Topol, Eric J, Baldwin, Kristin K, Torkamani, Ali
Published in Nature biotechnology (12.12.2016)
Published in Nature biotechnology (12.12.2016)
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Journal Article
Abstract 288: Novel Mechanisms of Non-coding Genomic Regulation Identified in Cardiac Disease-in-a-dish Models
Kumar, Aditya, Thomas, Stephanie, Wong, Kirsten, Tenerelli, Kevin, Lo Sardo, Valentina, Ferguson, William, Topol, Eric, Baldwin, Kristin, Engler, Adam
Published in Circulation research (22.07.2016)
Published in Circulation research (22.07.2016)
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Journal Article
Abstract 289: Improved Disease Modeling Reveals 9p21 Risk Allele Regulates Connexins to Induce Arrhythmic Phenotypes
Kumar, Aditya, Thomas, Stephanie, Wong, Kirsten, Lo Sardo, Valentina, Cheah, Daniel, Tenerelli, Kevin, Ferguson, William, Topol, Eric, Baldwin, Kristin, Engler, Adam
Published in Circulation research (21.07.2017)
Published in Circulation research (21.07.2017)
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Journal Article
Metabolic Dysregulation of the Lysophospholipid/Autotaxin Axis in the Chromosome 9p21 Gene SNP rs10757274
Meckelmann, Sven W, Hawksworth, Jade I, White, Daniel, Andrews, Robert, Rodrigues, Patricia, O'Connor, Anne, Alvarez-Jarreta, Jorge, Tyrrell, Victoria J, Hinz, Christine, Zhou, You, Williams, Julie, Aldrovandi, Maceler, Watkins, William J, Engler, Adam J, Lo Sardo, Valentina, Slatter, David A, Allen, Stuart M, Acharya, Jay, Mitchell, Jacquie, Cooper, Jackie, Aoki, Junken, Kano, Kuniyuki, Humphries, Steve E, O'Donnell, Valerie B
Published in Circulation. Genomic and precision medicine (01.06.2020)
Published in Circulation. Genomic and precision medicine (01.06.2020)
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