SUMO1 degrader induces ER stress and ROS accumulation through deSUMOylation of TCF4 and inhibition of its transcription of StarD7 in colon cancer
Zhao, Yin Quan, Jin, Hong Ri, Kim, Daeho, Jung, Sung Han, Liu, Sheng, Wan, Jun, Lo, Ho‐Yin, Fu, Xue Qi, Wang, Quan, Hao, Chunhai, Bellail, Anita C.
Published in Molecular carcinogenesis (01.09.2023)
Published in Molecular carcinogenesis (01.09.2023)
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Journal Article
Development of moral reasoning in situational and cultural contexts
Lo, Jesse Ho-Yin, Fu, Genyue, Lee, Kang, Cameron, Catherine Ann
Published in Journal of moral education (02.04.2020)
Published in Journal of moral education (02.04.2020)
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Journal Article
Brown grease pyrolysis under pressure: Extending the range of reaction conditions and hydrocarbon product distributions
Pratt, Lawrence M., Kim, Jihyun, Lo, Ho-Yin, Xiao, Dequan
Published in Fuel (Guildford) (01.04.2021)
Published in Fuel (Guildford) (01.04.2021)
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Journal Article
Cognitive impairment in Irritable Bowel Syndrome (IBS): A systematic review
Lam, Novem Ching-Yee, Yeung, Hoi-Yan, Li, Wai-Kiu, Lo, Ho-Yin, Yuen, Chun-Fong, Chang, Raymond Chuen-Chung, Ho, Yuen-Shan
Published in Brain research (15.09.2019)
Published in Brain research (15.09.2019)
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Journal Article
Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors
Bellail, Anita C, Jin, Hong Ri, Lo, Ho-Yin, Jung, Sung Han, Hamdouchi, Chafiq, Kim, Daeho, Higgins, Ryan K, Blanck, Maximilian, le Sage, Carlos, Cross, Benedict C S, Li, Jing, Mosley, Amber L, Wijeratne, Aruna B, Jiang, Wen, Ghosh, Manali, Zhao, Yin Quan, Hauck, Paula M, Shekhar, Anantha, Hao, Chunhai
Published in Science translational medicine (13.10.2021)
Published in Science translational medicine (13.10.2021)
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Journal Article
Substituted pyrazoles as novel sEH antagonist: Investigation of key binding interactions within the catalytic domain
Lo, Ho Yin, Man, Chuk C., Fleck, Roman W., Farrow, Neil A., Ingraham, Richard H., Kukulka, Alison, Proudfoot, John R., Betageri, Raj, Kirrane, Tom, Patel, Usha, Sharma, Rajiv, Hoermann, Mary Ann, Kabcenell, Alisa, Lombaert, Stéphane De
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
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Journal Article
Benzimidazolone as potent chymase inhibitor: Modulation of reactive metabolite formation in the hydrophobic (P 1) region
Lo, Ho Yin, Nemoto, Peter A., Kim, Jin Mi, Hao, Ming-Hong, Qian, Kevin C., Farrow, Neil A., Albaugh, Daniel R., Fowler, Danielle M., Schneiderman, Richard D., Michael August, E., Martin, Leslie, Hill-Drzewi, Melissa, Pullen, Steven S., Takahashi, Hidenori, De Lombaert, Stéphane
Published in Bioorganic & medicinal chemistry letters (01.08.2011)
Published in Bioorganic & medicinal chemistry letters (01.08.2011)
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Journal Article
Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)
MORIARTY, Kevin J, TAKAHASHI, Hidenori, LEI QIAO, RYAN, Declan, DESJARLAIS, Renee, ROBINSON, Darius, WILSON, Matthew, BOBKO, Mark, COOK, Brian N, HO YIN LO, NEMOTO, Peter A, KASHEM, Mohammed A, PULLEN, Steven S, WOLAK, John P, WHITE, André, MAGOLDA, Ronald L, TOMCZUK, Bruce, HNIN HNIN KHINE, SALLATI, Rosemarie H, RAYMOND, Ernest L, WOSKA, Joseph R, JEANFAVRE, Deborah D, ROTH, Gregory P, WINTERS, Michael P
Published in Bioorganic & medicinal chemistry (15.10.2008)
Published in Bioorganic & medicinal chemistry (15.10.2008)
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Journal Article
Cover Image, Volume 62, Issue 9
Zhao, Yin Quan, Jin, Hong Ri, Kim, Daeho, Jung, Sung Han, Liu, Sheng, Wan, Jun, Lo, Ho‐Yin, Fu, Xue Qi, Wang, Quan, Hao, Chunhai, Bellail, Anita C.
Published in Molecular carcinogenesis (01.09.2023)
Published in Molecular carcinogenesis (01.09.2023)
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Journal Article
Synthesis, SAR, and Series Evolution of Novel Oxadiazole-Containing 5‑Lipoxygenase Activating Protein Inhibitors: Discovery of 2‑[4-(3-{(R)‑1-[4-(2-Amino-pyrimidin-5-yl)-phenyl]-1-cyclopropyl-ethyl}-[1,2,4]oxadiazol-5-yl)-pyrazol-1-yl]‑N,N‑dimethyl-acetamide (BI 665915)
Takahashi, Hidenori, Riether, Doris, Bartolozzi, Alessandra, Bosanac, Todd, Berger, Valentina, Binetti, Ralph, Broadwater, John, Chen, Zhidong, Crux, Rebecca, De Lombaert, Stéphane, Dave, Rajvee, Dines, Jonathon A, Fadra-Khan, Tazmeen, Flegg, Adam, Garrigou, Michael, Hao, Ming-Hong, Huber, John, Hutzler, J. Matthew, Kerr, Steven, Kotey, Adrian, Liu, Weimin, Lo, Ho Yin, Loke, Pui Leng, Mahaney, Paige E, Morwick, Tina M, Napier, Spencer, Olague, Alan, Pack, Edward, Padyana, Anil K, Thomson, David S, Tye, Heather, Wu, Lifen, Zindell, Renee M, Abeywardane, Asitha, Simpson, Thomas
Published in Journal of medicinal chemistry (26.02.2015)
Published in Journal of medicinal chemistry (26.02.2015)
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Journal Article
2-Aminobenzimidazoles as potent ITK antagonists: de novo design of a pyrrole system targeting additional hydrogen bonding interaction
Lo, Ho Yin, Bentzien, Jörg, White, Andre, Man, Chuk C., Fleck, Roman W., Pullen, Steven S., Khine, Hnin Hnin, King, Josephine, Woska, Joseph R., Wolak, John P., Kashem, Mohammed A., Roth, Gregory P., Takahashi, Hidenori
Published in Tetrahedron letters (15.12.2008)
Published in Tetrahedron letters (15.12.2008)
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Journal Article
2-Aminobenzimidazoles as potent ITK antagonists: trans-stilbene-like moieties targeting the kinase specificity pocket
Lo, Ho Yin, Bentzien, Jörg, Fleck, Roman W, Pullen, Steven S, Khine, Hnin Hnin, Woska, Jr, Joseph R, Kugler, Stanley Z, Kashem, Mohammed A, Takahashi, Hidenori
Published in Bioorganic & medicinal chemistry (01.12.2008)
Published in Bioorganic & medicinal chemistry (01.12.2008)
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Journal Article