Type I and III interferons disrupt lung epithelial repair during recovery from viral infection
Major, Jack, Crotta, Stefania, Llorian, Miriam, McCabe, Teresa M, Gad, Hans Henrik, Priestnall, Simon L, Hartmann, Rune, Wack, Andreas
Published in Science (07.08.2020)
Published in Science (07.08.2020)
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USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer
Nelson, Jessica K., Thin, May Zaw, Evan, Theodore, Howell, Steven, Wu, Mary, Almeida, Bruna, Legrave, Nathalie, Koenis, Duco S., Koifman, Gabriela, Sugimoto, Yoichiro, Llorian Sopena, Miriam, MacRae, James, Nye, Emma, Howell, Michael, Snijders, Ambrosius P., Prachalias, Andreas, Zen, Yoh, Sarker, Debashis, Behrens, Axel
Published in Nature communications (19.04.2022)
Published in Nature communications (19.04.2022)
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Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection
Bradley, Konrad C., Finsterbusch, Katja, Schnepf, Daniel, Crotta, Stefania, Llorian, Miriam, Davidson, Sophia, Fuchs, Serge Y., Staeheli, Peter, Wack, Andreas
Published in Cell reports (Cambridge) (02.07.2019)
Published in Cell reports (Cambridge) (02.07.2019)
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Cell-intrinsic Aryl Hydrocarbon Receptor signalling is required for the resolution of injury-induced colonic stem cells
Shah, Kathleen, Maradana, Muralidhara Rao, Joaquina Delàs, M., Metidji, Amina, Graelmann, Frederike, Llorian, Miriam, Chakravarty, Probir, Li, Ying, Tolaini, Mauro, Shapiro, Michael, Kelly, Gavin, Cheshire, Chris, Bhurta, Deendyal, Bharate, Sandip B., Stockinger, Brigitta
Published in Nature communications (05.04.2022)
Published in Nature communications (05.04.2022)
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Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation
Crotta, Stefania, Villa, Matteo, Major, Jack, Finsterbusch, Katja, Llorian, Miriam, Carmeliet, Peter, Buescher, Joerg, Wack, Andreas
Published in Nature communications (13.02.2023)
Published in Nature communications (13.02.2023)
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IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes
Yang, Jie, Cornelissen, Ferry, Papazian, Natalie, Reijmers, Rogier M, Llorian, Miriam, Cupedo, Tom, Coles, Mark, Seddon, Benedict
Published in The Journal of experimental medicine (02.04.2018)
Published in The Journal of experimental medicine (02.04.2018)
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Impaired immune response drives age-dependent severity of COVID-19
Beer, Julius, Crotta, Stefania, Breithaupt, Angele, Ohnemus, Annette, Becker, Jan, Sachs, Benedikt, Kern, Lisa, Llorian, Miriam, Ebert, Nadine, Labroussaa, Fabien, Nhu Thao, Tran Thi, Trueeb, Bettina Salome, Jores, Joerg, Thiel, Volker, Beer, Martin, Fuchs, Jonas, Kochs, Georg, Wack, Andreas, Schwemmle, Martin, Schnepf, Daniel
Published in The Journal of experimental medicine (05.12.2022)
Published in The Journal of experimental medicine (05.12.2022)
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Identification of RBPMS as a mammalian smooth muscle master splicing regulator via proximity of its gene with super-enhancers
Nakagaki-Silva, Erick E, Gooding, Clare, Llorian, Miriam, Jacob, Aishwarya G, Richards, Frederick, Buckroyd, Adrian, Sinha, Sanjay, Smith, Christopher Wj
Published in eLife (08.07.2019)
Published in eLife (08.07.2019)
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Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB
Smith, Christopher W J, Llorian, Miriam, Schwartz, Schraga, Clark, Tyson A, Hollander, Dror, Tan, Lit-Yeen, Spellman, Rachel, Gordon, Adele, Schweitzer, Anthony C, de la Grange, Pierre, Ast, Gil
Published in Nature structural & molecular biology (01.09.2010)
Published in Nature structural & molecular biology (01.09.2010)
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Alternative splicing: global insights
Hallegger, Martina, Llorian, Miriam, Smith, Christopher W.J
Published in The FEBS journal (01.02.2010)
Published in The FEBS journal (01.02.2010)
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Critical role of WNK1 in MYC-dependent early mouse thymocyte development
Köchl, Robert, Vanes, Lesley, Llorian Sopena, Miriam, Chakravarty, Probir, Hartweger, Harald, Fountain, Kathryn, White, Andrea, Cowan, Jennifer, Anderson, Graham, Tybulewicz, Victor Lj
Published in eLife (14.10.2020)
Published in eLife (14.10.2020)
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The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators
Llorian, Miriam, Gooding, Clare, Bellora, Nicolas, Hallegger, Martina, Buckroyd, Adrian, Wang, Xiao, Rajgor, Dipen, Kayikci, Melis, Feltham, Jack, Ule, Jernej, Eyras, Eduardo, Smith, Christopher W J
Published in Nucleic acids research (14.10.2016)
Published in Nucleic acids research (14.10.2016)
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Dual RNA Processing Roles of Pat1b via Cytoplasmic Lsm1-7 and Nuclear Lsm2-8 Complexes
Vindry, Caroline, Marnef, Aline, Broomhead, Helen, Twyffels, Laure, Ozgur, Sevim, Stoecklin, Georg, Llorian, Miriam, Smith, Christopher W., Mata, Juan, Weil, Dominique, Standart, Nancy
Published in Cell reports (Cambridge) (01.08.2017)
Published in Cell reports (Cambridge) (01.08.2017)
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Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes
Lana-Elola, Eva, Cater, Heather, Watson-Scales, Sheona, Greenaway, Simon, Müller-Winkler, Jennifer, Gibbins, Dorota, Nemes, Mihaela, Slender, Amy, Hough, Tertius, Keskivali-Bond, Piia, Scudamore, Cheryl L, Herbert, Eleanor, Banks, Gareth T, Mobbs, Helene, Canonica, Tara, Tosh, Justin, Noy, Suzanna, Llorian, Miriam, Nolan, Patrick M, Griffin, Julian L, Good, Mark, Simon, Michelle, Mallon, Ann-Marie, Wells, Sara, Fisher, Elizabeth M C, Tybulewicz, Victor L J
Published in Disease models & mechanisms (01.10.2021)
Published in Disease models & mechanisms (01.10.2021)
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Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation
Păun, Oana, Tan, Yu Xuan, Patel, Harshil, Strohbuecker, Stephanie, Ghanate, Avinash, Cobolli-Gigli, Clementina, Llorian Sopena, Miriam, Gerontogianni, Lina, Goldstone, Robert, Ang, Siew-Lan, Guillemot, François, Dias, Cristina
Published in Genes & development (01.03.2023)
Published in Genes & development (01.03.2023)
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Defining the roles and interactions of PTB
Kafasla, Panagiota, Mickleburgh, Ian, Llorian, Miriam, Coelho, Miguel, Gooding, Clare, Cherny, Dmitry, Joshi, Amar, Kotik-Kogan, Olga, Curry, Stephen, Eperon, Ian C, Jackson, Richard J, Smith, Christopher W J
Published in Biochemical Society transactions (01.08.2012)
Published in Biochemical Society transactions (01.08.2012)
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Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils
Huerga Encabo, Hector, Aramburu, Iker Valle, Garcia-Albornoz, Manuel, Piganeau, Marion, Wood, Henry, Song, Anna, Ferrelli, Alessandra, Sharma, Aneesh, Minutti, Carlos M., Domart, Marie-Charlotte, Papazoglou, Despoina, Gurashi, Kristian, Llorian Sopena, Miriam, Goldstone, Robert, Fallesen, Todd, Wang, Qian, Ariza-McNaughton, Linda, Wiseman, Daniel H., Batta, Kiran, Gupta, Rajeev, Papayannopoulos, Venizelos, Bonnet, Dominique
Published in Cell stem cell (01.06.2023)
Published in Cell stem cell (01.06.2023)
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Polypyrimidine tract‐binding protein binds to the 5′ untranslated region of the mouse mammary tumor virus mRNA and stimulates cap‐independent translation initiation
Cáceres, Carlos J., Contreras, Nataly, Angulo, Jenniffer, Vera‐Otarola, Jorge, Pino‐Ajenjo, Constanza, Llorian, Miriam, Ameur, Melissa, Lisboa, Francisco, Pino, Karla, Lowy, Fernando, Sargueil, Bruno, López‐Lastra, Marcelo
Published in The FEBS journal (01.05.2016)
Published in The FEBS journal (01.05.2016)
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Therapeutic KRASG12C inhibition drives effective interferon-mediated antitumor immunity in immunogenic lung cancers
Mugarza, Edurne, van Maldegem, Febe, Boumelha, Jesse, Moore, Christopher, Rana, Sareena, Llorian Sopena, Miriam, East, Philip, Ambler, Rachel, Anastasiou, Panayiotis, Romero-Clavijo, Pablo, Valand, Karishma, Cole, Megan, Molina-Arcas, Miriam, Downward, Julian
Published in Science advances (22.07.2022)
Published in Science advances (22.07.2022)
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