sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers
Suárez‐Calvet, Marc, Kleinberger, Gernot, Araque Caballero, Miguel Ángel, Brendel, Matthias, Rominger, Axel, Alcolea, Daniel, Fortea, Juan, Lleó, Alberto, Blesa, Rafael, Gispert, Juan Domingo, Sánchez‐Valle, Raquel, Antonell, Anna, Rami, Lorena, Molinuevo, José L, Brosseron, Frederic, Traschütz, Andreas, Heneka, Michael T, Struyfs, Hanne, Engelborghs, Sebastiaan, Sleegers, Kristel, Van Broeckhoven, Christine, Zetterberg, Henrik, Nellgård, Bengt, Blennow, Kaj, Crispin, Alexander, Ewers, Michael, Haass, Christian
Published in EMBO molecular medicine (01.05.2016)
Published in EMBO molecular medicine (01.05.2016)
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Blood Biomarkers in Neurodegenerative Diseases: Implications for the Clinical Neurologist
Alcolea, Daniel, Beeri, Michal Schnaider, Rojas, Julio C, Gardner, Raquel C, Lleó, Alberto
Published in Neurology (25.07.2023)
Published in Neurology (25.07.2023)
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YKL-40 (Chitinase 3-like I) is expressed in a subset of astrocytes in Alzheimer's disease and other tauopathies
Querol-Vilaseca, Marta, Colom-Cadena, Martí, Pegueroles, Jordi, San Martín-Paniello, Carla, Clarimon, Jordi, Belbin, Olivia, Fortea, Juan, Lleó, Alberto
Published in Journal of neuroinflammation (09.06.2017)
Published in Journal of neuroinflammation (09.06.2017)
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Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study
Fortea, Juan, Vilaplana, Eduard, Carmona-Iragui, Maria, Benejam, Bessy, Videla, Laura, Barroeta, Isabel, Fernández, Susana, Altuna, Miren, Pegueroles, Jordi, Montal, Víctor, Valldeneu, Silvia, Giménez, Sandra, González-Ortiz, Sofía, Muñoz, Laia, Estellés, Teresa, Illán-Gala, Ignacio, Belbin, Olivia, Camacho, Valle, Wilson, Liam Reese, Annus, Tiina, Osorio, Ricardo S, Videla, Sebastián, Lehmann, Sylvain, Holland, Anthony J, Alcolea, Daniel, Clarimón, Jordi, Zaman, Shahid H, Blesa, Rafael, Lleó, Alberto
Published in The Lancet (British edition) (27.06.2020)
Published in The Lancet (British edition) (27.06.2020)
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Plasma and CSF biomarkers for the diagnosis of Alzheimer's disease in adults with Down syndrome: a cross-sectional study
Fortea, Juan, Carmona-Iragui, María, Benejam, Bessy, Fernández, Susana, Videla, Laura, Barroeta, Isabel, Alcolea, Daniel, Pegueroles, Jordi, Muñoz, Laia, Belbin, Olivia, de Leon, Mony J, Maceski, Aleksandra Maleska, Hirtz, Christophe, Clarimón, Jordi, Videla, Sebastián, Delaby, Constance, Lehmann, Sylvain, Blesa, Rafael, Lleó, Alberto
Published in Lancet neurology (01.10.2018)
Published in Lancet neurology (01.10.2018)
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Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology
Ashton, Nicholas J, Brum, Wagner S, Di Molfetta, Guglielmo, Benedet, Andrea L, Arslan, Burak, Jonaitis, Erin, Langhough, Rebecca E, Cody, Karly, Wilson, Rachael, Carlsson, Cynthia M, Vanmechelen, Eugeen, Montoliu-Gaya, Laia, Lantero-Rodriguez, Juan, Rahmouni, Nesrine, Tissot, Cecile, Stevenson, Jenna, Servaes, Stijn, Therriault, Joseph, Pascoal, Tharick, Lleó, Alberto, Alcolea, Daniel, Fortea, Juan, Rosa-Neto, Pedro, Johnson, Sterling, Jeromin, Andreas, Blennow, Kaj, Zetterberg, Henrik
Published in Archives of neurology (Chicago) (01.03.2024)
Published in Archives of neurology (Chicago) (01.03.2024)
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APOE4 homozygozity represents a distinct genetic form of Alzheimer's disease
Fortea, Juan, Pegueroles, Jordi, Alcolea, Daniel, Belbin, Olivia, Dols-Icardo, Oriol, Vaqué-Alcázar, Lídia, Videla, Laura, Gispert, Juan Domingo, Suárez-Calvet, Marc, Johnson, Sterling C, Sperling, Reisa, Bejanin, Alexandre, Lleó, Alberto, Montal, Víctor
Published in Nature medicine (01.05.2024)
Published in Nature medicine (01.05.2024)
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Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors
Powers, Rani K., Culp-Hill, Rachel, Ludwig, Michael P., Smith, Keith P., Waugh, Katherine A., Minter, Ross, Tuttle, Kathryn D., Lewis, Hannah C., Rachubinski, Angela L., Granrath, Ross E., Carmona-Iragui, María, Wilkerson, Rebecca B., Kahn, Darcy E., Joshi, Molishree, Lleó, Alberto, Blesa, Rafael, Fortea, Juan, D’Alessandro, Angelo, Costello, James C., Sullivan, Kelly D., Espinosa, Joaquin M.
Published in Nature communications (18.10.2019)
Published in Nature communications (18.10.2019)
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Nanoscale structure of amyloid-β plaques in Alzheimer’s disease
Querol-Vilaseca, Marta, Colom-Cadena, Martí, Pegueroles, Jordi, Nuñez-Llaves, Raúl, Luque-Cabecerans, Joan, Muñoz-Llahuna, Laia, Andilla, Jordi, Belbin, Olivia, Spires-Jones, Tara L., Gelpi, Ellen, Clarimon, Jordi, Loza-Alvarez, Pablo, Fortea, Juan, Lleó, Alberto
Published in Scientific reports (26.03.2019)
Published in Scientific reports (26.03.2019)
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Amyloid precursor protein metabolism and inflammation markers in preclinical Alzheimer disease
Alcolea, Daniel, Martínez-Lage, Pablo, Sánchez-Juan, Pascual, Olazarán, Javier, Antúnez, Carmen, Izagirre, Andrea, Ecay-Torres, Mirian, Estanga, Ainara, Clerigué, Montserrat, Guisasola, Maria Concepción, Sánchez Ruiz, Domingo, Marín Muñoz, Juan, Calero, Miguel, Blesa, Rafael, Clarimón, Jordi, Carmona-Iragui, María, Morenas-Rodríguez, Estrella, Rodríguez-Rodríguez, Eloy, Vázquez Higuera, José Luis, Fortea, Juan, Lleó, Alberto
Published in Neurology (18.08.2015)
Published in Neurology (18.08.2015)
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Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain
Colom-Cadena, Martí, Davies, Caitlin, Sirisi, Sònia, Lee, Ji-Eun, Simzer, Elizabeth M., Tzioras, Makis, Querol-Vilaseca, Marta, Sánchez-Aced, Érika, Chang, Ya Yin, Holt, Kristjan, McGeachan, Robert I., Rose, Jamie, Tulloch, Jane, Wilkins, Lewis, Smith, Colin, Andrian, Teodora, Belbin, Olivia, Pujals, Sílvia, Horrocks, Mathew H., Lleó, Alberto, Spires-Jones, Tara L.
Published in Neuron (Cambridge, Mass.) (19.07.2023)
Published in Neuron (Cambridge, Mass.) (19.07.2023)
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Altered microRNAs related to synaptic function as potential plasma biomarkers for Alzheimer's disease
Siedlecki-Wullich, Dolores, Català-Solsona, Judit, Fábregas, Cristina, Hernández, Isabel, Clarimon, Jordi, Lleó, Alberto, Boada, Merce, Saura, Carlos A, Rodríguez-Álvarez, José, Miñano-Molina, Alfredo J
Published in Alzheimer's research & therapy (15.05.2019)
Published in Alzheimer's research & therapy (15.05.2019)
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The proton-pump inhibitor lansoprazole enhances amyloid beta production
Badiola, Nahuai, Alcalde, Victor, Pujol, Albert, Münter, Lisa-Marie, Multhaup, Gerd, Lleó, Alberto, Coma, Mireia, Soler-López, Montserrat, Aloy, Patrick
Published in PloS one (08.03.2013)
Published in PloS one (08.03.2013)
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Decreased CX3CL1 Levels in the Cerebrospinal Fluid of Patients With Alzheimer's Disease
Perea, Juan R, Lleó, Alberto, Alcolea, Daniel, Fortea, Juan, Ávila, Jesús, Bolós, Marta
Published in Frontiers in neuroscience (07.09.2018)
Published in Frontiers in neuroscience (07.09.2018)
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Neuropsychological deficits in patients with cognitive complaints after COVID‐19
García‐Sánchez, Carmen, Calabria, Marco, Grunden, Nicholas, Pons, Catalina, Arroyo, Juan Antonio, Gómez‐Anson, Beatriz, Lleó, Alberto, Alcolea, Daniel, Belvís, Roberto, Morollón, Noemí, Mur, Isabel, Pomar, Virginia, Domingo, Pere
Published in Brain and Behavior (01.03.2022)
Published in Brain and Behavior (01.03.2022)
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CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer´s disease
del Campo, Marta, Vermunt, Lisa, Peeters, Carel F. W., Sieben, Anne, Hok-A-Hin, Yanaika S., Lleó, Alberto, Alcolea, Daniel, van Nee, Mirrelijn, Engelborghs, Sebastiaan, van Alphen, Juliette L., Arezoumandan, Sanaz, Chen-Plotkin, Alice, Irwin, David J., van der Flier, Wiesje M., Lemstra, Afina W., Teunissen, Charlotte E.
Published in Nature communications (13.09.2023)
Published in Nature communications (13.09.2023)
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Changes in Synaptic Proteins Precede Neurodegeneration Markers in Preclinical Alzheimer's Disease Cerebrospinal Fluid
Lleó, Alberto, Núñez-Llaves, Raúl, Alcolea, Daniel, Chiva, Cristina, Balateu-Paños, Daniel, Colom-Cadena, Martí, Gomez-Giro, Gemma, Muñoz, Laia, Querol-Vilaseca, Marta, Pegueroles, Jordi, Rami, Lorena, Lladó, Albert, Molinuevo, José L., Tainta, Mikel, Clarimón, Jordi, Spires-Jones, Tara, Blesa, Rafael, Fortea, Juan, Martínez-Lage, Pablo, Sánchez-Valle, Raquel, Sabidó, Eduard, Bayés, Àlex, Belbin, Olivia
Published in Molecular & cellular proteomics (01.03.2019)
Published in Molecular & cellular proteomics (01.03.2019)
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