Transthyretin neuroprotection in Alzheimer's disease is dependent on proteolysis
Silva, Catarina S., Eira, Jessica, Ribeiro, Carlos A., Oliveira, Ângela, Sousa, Mónica M., Cardoso, Isabel, Liz, Márcia A.
Published in Neurobiology of aging (01.11.2017)
Published in Neurobiology of aging (01.11.2017)
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Journal Article
Profilin 1 delivery tunes cytoskeletal dynamics toward CNS axon regeneration
Pinto-Costa, Rita, Sousa, Sara C, Leite, Sérgio C, Nogueira-Rodrigues, Joana, Ferreira da Silva, Tiago, Machado, Diana, Marques, Joana, Costa, Ana Catarina, Liz, Márcia A, Bartolini, Francesca, Brites, Pedro, Costell, Mercedes, Fässler, Reinhard, Sousa, Mónica M
Published in The Journal of clinical investigation (01.04.2020)
Published in The Journal of clinical investigation (01.04.2020)
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Journal Article
Targeting transthyretin in Alzheimer's disease: Drug discovery of small-molecule chaperones as disease-modifying drug candidates for Alzheimer's disease
Cotrina, Ellen Y., Santos, Luis Miguel, Rivas, Josep, Blasi, Daniel, Leite, José Pedro, Liz, Márcia A., Busquets, Maria Antònia, Planas, Antoni, Prohens, Rafel, Gimeno, Ana, Jiménez-Barbero, Jesús, Gales, Luis, Llop, Jordi, Quintana, Jordi, Cardoso, Isabel, Arsequell, Gemma
Published in European journal of medicinal chemistry (15.12.2021)
Published in European journal of medicinal chemistry (15.12.2021)
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Journal Article
Transthyretin interacts with actin regulators in a Drosophila model of familial amyloid polyneuropathy
I. Oliveira da Silva, Marina, Lopes, Carla S., Liz, Márcia A.
Published in Scientific reports (12.08.2020)
Published in Scientific reports (12.08.2020)
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Journal Article
Linking Alpha-Synuclein to the Actin Cytoskeleton: Consequences to Neuronal Function
Oliveira da Silva, Marina I., Liz, Márcia A.
Published in Frontiers in cell and developmental biology (12.08.2020)
Published in Frontiers in cell and developmental biology (12.08.2020)
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Journal Article
Design, Synthesis, and Biological Evaluation of Hybrid Glypromate Analogues Using 2‑Azanorbornane as a Prolyl and Pipecolyl Surrogate
Sampaio-Dias, Ivo E, Santejo, Miguel, Silva-Reis, Sara C, Liz, Márcia A, Alcoholado, Cristina, Algarra, Manuel, García-Mera, Xerardo, Rodríguez-Borges, José E
Published in ACS chemical neuroscience (06.10.2021)
Published in ACS chemical neuroscience (06.10.2021)
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Journal Article
α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway
Oliveira da Silva, Marina I., Santejo, Miguel, Babcock, Isaac W., Magalhães, Ana, Minamide, Laurie S., Won, Seok-Joon, Castillo, Erika, Gerhardt, Ellen, Fahlbusch, Christiane, Swanson, Raymond A., Outeiro, Tiago F., Taipa, Ricardo, Ruff, Michael, Bamburg, James R., Liz, Márcia A.
Published in Cell death & disease (13.04.2024)
Published in Cell death & disease (13.04.2024)
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Journal Article
Transthyretin is a metallopeptidase with an inducible active site
Liz, Márcia A, Leite, Sérgio C, Juliano, Luiz, Saraiva, Maria J, Damas, Ana M, Bur, Daniel, Sousa, Mónica M
Published in Biochemical journal (01.05.2012)
Published in Biochemical journal (01.05.2012)
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Journal Article
Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2
Liz, Márcia A, Mar, Fernando M, Santos, Telma E, Pimentel, Helena I, Marques, Ana M, Morgado, Marlene M, Vieira, Sílvia, Sousa, Vera F, Pemble, Hayley, Wittmann, Torsten, Sutherland, Calum, Woodgett, James R, Sousa, Mónica M
Published in BMC biology (12.06.2014)
Published in BMC biology (12.06.2014)
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Journal Article
Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation
Eira, Jessica, Magalhães, Joana, Macedo, Nídia, Pero, Maria Elena, Misgeld, Thomas, Sousa, Mónica M., Bartolini, Francesca, Liz, Márcia A.
Published in Frontiers in cell and developmental biology (08.11.2021)
Published in Frontiers in cell and developmental biology (08.11.2021)
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Journal Article
Aboard transthyretin: From transport to cleavage
Liz, Márcia A, Mar, Fernando M, Franquinho, Filipa, Sousa, Mónica M
Published in IUBMB life (01.06.2010)
Published in IUBMB life (01.06.2010)
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Journal Article
Neuropeptide Y expression and function during osteoblast differentiation - insights from transthyretin knockout mice
Nunes, Ana F, Liz, Márcia A, Franquinho, Filipa, Teixeira, Liliana, Sousa, Vera, Chenu, Chantal, Lamghari, Meriem, Sousa, Mónica M
Published in The FEBS journal (2010)
Published in The FEBS journal (2010)
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Journal Article
Substrate specificity of transthyretin: identification of natural substrates in the nervous system
Liz, Márcia A, Fleming, Carolina E, Nunes, Ana F, Almeida, Maria R, Mar, Fernando M, Choe, Youngchool, Craik, Charles S, Powers, James C, Bogyo, Matthew, Sousa, Mónica M
Published in Biochemical journal (15.04.2009)
Published in Biochemical journal (15.04.2009)
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Journal Article
Neuronal deletion of GSK3[beta] increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2
Liz, Márcia A, Mar, Fernando M, Santos, Telma E, Pimentel, Helena I, Marques, Ana M, Morgado, Marlene M, Vieira, Sílvia, Sousa, Vera F, Pemble, Hayley, Wittmann, Torsten, Sutherland, Calum, Woodgett, James R, Sousa, Mónica M
Published in BMC biology (12.06.2014)
Published in BMC biology (12.06.2014)
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Journal Article
Modulating vitamin C transport in hippocampal microglia to target synapse and memory deficits in Parkinson’s Disease
Portugal, Camila C., Pacheco, Ana M., Santos, Evelyn C.S., Liz, Márcia A., Socodato, Renato, Relvas, Joao B.
Published in Free radical biology & medicine (01.06.2024)
Published in Free radical biology & medicine (01.06.2024)
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Journal Article
α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrP C -CCR5 dependent pathway
Oliveira da Silva, Marina I, Santejo, Miguel, Babcock, Isaac W, Magalhães, Ana, Minamide, Laurie S, Won, Seok-Joon, Castillo, Erika, Gerhardt, Ellen, Fahlbusch, Christiane, Swanson, Raymond A, Outeiro, Tiago F, Taipa, Ricardo, Ruff, Michael, Bamburg, James R, Liz, Márcia A
Published in Cell death & disease (13.04.2024)
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Published in Cell death & disease (13.04.2024)
Journal Article