Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3‑Kinase δ for the Treatment of Respiratory Disease
Down, Kenneth, Amour, Augustin, Baldwin, Ian R, Cooper, Anthony W. J, Deakin, Angela M, Felton, Leigh M, Guntrip, Stephen B, Hardy, Charlotte, Harrison, Zoë A, Jones, Katherine L, Jones, Paul, Keeling, Suzanne E, Le, Joelle, Livia, Stefano, Lucas, Fiona, Lunniss, Christopher J, Parr, Nigel J, Robinson, Ed, Rowland, Paul, Smith, Sarah, Thomas, Daniel A, Vitulli, Giovanni, Washio, Yoshiaki, Hamblin, J. Nicole
Published in Journal of medicinal chemistry (24.09.2015)
Published in Journal of medicinal chemistry (24.09.2015)
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Journal Article
Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity Target
Henley, Zoë A, Amour, Augustin, Barton, Nick, Bantscheff, Marcus, Bergamini, Giovanna, Bertrand, Sophie M, Convery, Máire, Down, Kenneth, Dümpelfeld, Birgit, Edwards, Chris D, Grandi, Paola, Gore, Paul M, Keeling, Steve, Livia, Stefano, Mallett, David, Maxwell, Aoife, Price, Mark, Rau, Christina, Reinhard, Friedrich B. M, Rowedder, James, Rowland, Paul, Taylor, Jonathan A, Thomas, Daniel A, Hessel, Edith M, Hamblin, J. Nicole
Published in Journal of medicinal chemistry (23.01.2020)
Published in Journal of medicinal chemistry (23.01.2020)
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Journal Article
Design and development of arrayable syntheses to accelerate SAR studies of pyridopyrimidinone and pyrimidopyrimidinone
Wan, Zehong, Yan, Hongxing, Hall, Ralph F., Lin, Xichen, Livia, Stefano, Respondek, Tomasz, Widdowson, Katherine L., Zhu, Chongjie, Callahan, James F.
Published in Tetrahedron letters (21.01.2009)
Published in Tetrahedron letters (21.01.2009)
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Journal Article
Pyrimidopyridine compound used as a CSBP/RK/p38 modulator
COOPER, ANTHONY, WILLIAM, JAMES, BOEHM, JEFFREY, C, NEVINS, NEYSA, NORTON, BETH, A, LIVIA, STEFANO, WAN, ZEHONG, CALLAHAN, JAMES, FRANCIS
Year of Publication 12.06.2013
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Year of Publication 12.06.2013
Patent
8-PHENYL-7,8-DIHYDROPYRIDO[2,3-d]PYRIMIDIN-7-ONES
COOPER, ANTHONY, WILLIAM, JAMES, BOEHM, JEFFREY, C, NEVINS, NEYSA, NORTON, BETH, A, LIVIA, STEFANO, WAN, ZEHONG, CALLAHAN, JAMES, FRANCIS
Year of Publication 14.11.2012
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Year of Publication 14.11.2012
Patent
Pyrimidopyridine compound used as a CSBP/RK/p38 modulator
COOPER, ANTHONY, WILLIAM, JAMES, BOEHM, JEFFREY, C, NEVINS, NEYSA, NORTON, BETH, A, LIVIA, STEFANO, WAN, ZEHONG, CALLAHAN, JAMES, FRANCIS
Year of Publication 02.05.2012
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Year of Publication 02.05.2012
Patent
Pyrimidopyridine compound used as a CSBP/RK/p38 modulator
COOPER, ANTHONY, WILLIAM, JAMES, BOEHM, JEFFREY, C, NEVINS, NEYSA, NORTON, BETH, A, LIVIA, STEFANO, WAN, ZEHONG, CALLAHAN, JAMES, FRANCIS
Year of Publication 04.04.2012
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Year of Publication 04.04.2012
Patent
NOVEL COMPOUNDS
STEFANO LIVIA, JAMES FRANCIS CALLAHAN, BETH A NORTON, JEFFREY C. BOEHM, ANTHONY WILLIAM JAMES COOPER, WAN ZEHONG, NEYSA NEVINS
Year of Publication 31.01.2012
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Year of Publication 31.01.2012
Patent
NOVEL COMPOUNDS
STEFANO LIVIA, JAMES FRANCIS CALLAHAN, BETH A NORTON, JEFFREY C. BOEHM, ANTHONY WILLIAM JAMES COOPER, WAN ZEHONG, NEYSA NEVINS
Year of Publication 13.01.2012
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Year of Publication 13.01.2012
Patent
Compounds
BOEHM JEFFREY C, BAMBOROUGH PAUL, CALLAHAN JAMES F, COOPER ANTHONY WILLIAM JAMES, LIN XICHEN, LIVIA STEFANO, WAN ZEHONG, NEVINS NEYSA, NORTON BETH A
Year of Publication 26.06.2012
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Year of Publication 26.06.2012
Patent
Compounds
Callahan, James F, Boehm, Jeffrey C, Cooper, Anthony William James, Livia, Stefano, Bamborough, Paul, Nevins, Neysa, Wan, Zehong, Norton, Beth A, Lin, Xichen
Year of Publication 26.06.2012
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Year of Publication 26.06.2012
Patent
NOVEL COMPOUNDS
COOPER, ANTHONY, WILLIAM, JAMES, BOEHM, JEFFREY, C, NEVINS, NEYSA, NORTON, BETH, A, LIVIA, STEFANO, WAN, ZEHONG, CALLAHAN, JAMES, FRANCIS
Year of Publication 29.12.2010
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Year of Publication 29.12.2010
Patent
NOVEL COMPOUNDS
COOPER, ANTHONY, WILLIAM, JAMES, BOEHM, JEFFREY, C, NEVINS, NEYSA, NORTON, BETH, A, LIVIA, STEFANO, WAN, ZEHONG, CALLAHAN, JAMES, FRANCIS
Year of Publication 27.05.2009
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Year of Publication 27.05.2009
Patent
Novel Compounds
COOPER, ANTHONY, WILLIAM, JAMES, BOEHM, JEFFREY, C, NEVINS, NEYSA, NORTON, BETH, A, LIVIA, STEFANO, WAN, ZEHONG, CALLAHAN, JAMES, FRANCIS
Year of Publication 29.10.2008
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Year of Publication 29.10.2008
Patent
Compounds
BOEHM JEFFREY C, BAMBOROUGH PAUL, CALLAHAN JAMES F, COOPER ANTHONY WILLIAM JAMES, LIN XICHEN, LIVIA STEFANO, WAN ZEHONG, NEVINS NEYSA, NORTON BETH A
Year of Publication 16.03.2010
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Year of Publication 16.03.2010
Patent