Serum-induced monocyte differentiation and monocyte chemotaxis are regulated by the p38 MAP kinase signal transduction pathway
Ayala, Julia M., Goyal, Shefali, Liverton, Nigel J., Claremon, Dave A., O'Keefe, Stephen J., Hanlon, William A.
Published in Journal of leukocyte biology (01.06.2000)
Published in Journal of leukocyte biology (01.06.2000)
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Nonpeptide glycoprotein IIb/IIIa inhibitors: Substituted quinazolinediones and quinazolinones as potent fibrinogen receptor antagonists
Liverton, Nigel J., Armstrong, Donna J., Claremon, David A., Remy, David C., Baldvin, John J., Lynch, Robert J., Zhang, Guixiang, Gould, Robert J.
Published in Bioorganic & medicinal chemistry letters (03.03.1998)
Published in Bioorganic & medicinal chemistry letters (03.03.1998)
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Design and Synthesis of Potent, Selective, and Orally Bioavailable Tetrasubstituted Imidazole Inhibitors of p38 Mitogen-Activated Protein Kinase
Liverton, Nigel J, Butcher, John W, Claiborne, Christopher F, Claremon, David A, Libby, Brian E, Nguyen, Kevin T, Pitzenberger, Steven M, Selnick, Harold G, Smith, Garry R, Tebben, Andrew, Vacca, Joseph P, Varga, Sandor L, Agarwal, Lily, Dancheck, Kim, Forsyth, Amy J, Fletcher, Daniel S, Frantz, Betsy, Hanlon, William A, Harper, Coral F, Hofsess, Scott J, Kostura, Matthew, Lin, Jiunn, Luell, Sylvie, O'Neill, Edward A, Orevillo, Chad J, Pang, Margaret, Parsons, Janey, Rolando, Anna, Sahly, Yousif, Visco, Denise M, O'Keefe, Stephen J
Published in Journal of medicinal chemistry (17.06.1999)
Published in Journal of medicinal chemistry (17.06.1999)
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Total synthesis of (+)-latrunculin B
Zibuck, Regina, Liverton, Nigel J, Smith, Amos B
Published in Journal of the American Chemical Society (01.04.1986)
Published in Journal of the American Chemical Society (01.04.1986)
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Journal Article
Design and Synthesis of Novel Isoquinoline-3-nitriles as Orally Bioavailable Kv1.5 Antagonists for the Treatment of Atrial Fibrillation
Trotter, B. Wesley, Nanda, Kausik K, Kett, Nathan R, Regan, Christopher P, Lynch, Joseph J, Stump, Gary L, Kiss, Laszlo, Wang, Jixin, Spencer, Robert H, Kane, Stefanie A, White, Rebecca B, Zhang, Rena, Anderson, Kenneth D, Liverton, Nigel J, McIntyre, Charles J, Beshore, Douglas C, Hartman, George D, Dinsmore, Christopher J
Published in Journal of medicinal chemistry (30.11.2006)
Published in Journal of medicinal chemistry (30.11.2006)
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Journal Article
Total synthesis of (+)-latrunculin A
Smith, Amos B., Noda, Ichio, Remiszewski, Stacy W., Liverton, Nigel J., Zibuck, Regina
Published in Journal of organic chemistry (01.06.1990)
Published in Journal of organic chemistry (01.06.1990)
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Journal Article
Class III Antiarrhythmic Activity in Vivo by Selective Blockade of the Slowly Activating Cardiac Delayed Rectifier Potassium Current IKs by (R)-2-(2,4- Trifluoromethyl)-N-[2-oxo-5-phenyl- 1-(2,2,2-trifluoroethyl)-2,3-dihydro- 1H-benzo[e][1,4]diazepin-3-yl]acetamide
SELNICK, Harold G., LIVERTON, Nigel J., BALDWIN, John J., BUTCHER, John W., CLAREMON, David A., ELLIOTT, Jason M., FREIDINGER, Roger M., KING, Stella A., LIBBY, Brian E., MCINTYRE, Charles J., PRIBUSH, David A., REMY, David C., SMITH, Garry R., TEBBEN, Andrew J., JURKIEWICZ, Nancy K., LYNCH, Joseph J., SALATA, Joseph J., SANGUINETTI, Michael C., SIEGL, Peter K. S., SLAUGHTER, Donald E., VYAS, Kamlesh
Published in Journal of medicinal chemistry (21.11.1997)
Published in Journal of medicinal chemistry (21.11.1997)
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Journal Article
Adenosine-2′-monophosphate derivatives: Structural requirements as substrates for inositol monophosphatase
Leeson, Paul D., James, Kim, Lennon, Ian C., Liverton, Nigel J., Aspley, Sue, Jackson, Rosamond G.
Published in Bioorganic & medicinal chemistry letters (01.10.1993)
Published in Bioorganic & medicinal chemistry letters (01.10.1993)
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Journal Article
An efficient photochemical approach to the trans-bicyclo[5.1.0]octene ring system
Wood, John L, Liverton, Nigel J, Visnick, Melean, Smith, Amos B
Published in Journal of the American Chemical Society (01.06.1989)
Published in Journal of the American Chemical Society (01.06.1989)
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Journal Article
A total synthesis of zoapatanol
COOKSON, R. C, LIVERTON, N. J
Published in Journal of the Chemical Society, Perkin Transactions 1 (1985)
Published in Journal of the Chemical Society, Perkin Transactions 1 (1985)
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Journal Article
Antiarrhythmic efficacy of selective blockade of the cardiac slowly activating delayed rectifier current, I(Ks), in canine models of malignant ischemic ventricular arrhythmia
Lynch, Jr, J J, Houle, M S, Stump, G L, Wallace, A A, Gilberto, D B, Jahansouz, H, Smith, G R, Tebben, A J, Liverton, N J, Selnick, H G, Claremon, D A, Billman, G E
Published in Circulation (New York, N.Y.) (02.11.1999)
Published in Circulation (New York, N.Y.) (02.11.1999)
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Journal Article
An efficient synthesis of tetrasubstituted imidazoles from N-(2-Oxo)-amides
Claiborne, Christopher F., Liverton, Nigel J., Nguyen, Kevin T.
Published in Tetrahedron letters (03.12.1998)
Published in Tetrahedron letters (03.12.1998)
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Journal Article
NR2B-Selective N-Methyl-d-aspartate Antagonists: Synthesis and Evaluation of 5-Substituted Benzimidazoles
McCauley, John A., Theberge, Cory R., Romano, Joseph J., Billings, Susan B., Anderson, Kenneth D., Claremon, David A., Freidinger, Roger M., Bednar, Rodney A., Mosser, Scott D., Gaul, Stanley L., Connolly, Thomas M., Condra, Cindra L., Xia, Menghang, Cunningham, Michael E., Bednar, Bohumil, Stump, Gary L., Lynch, Joseph J., Macaulay, Alison, Wafford, Keith A., Koblan, Kenneth S., Liverton, Nigel J.
Published in Journal of medicinal chemistry (08.04.2004)
Published in Journal of medicinal chemistry (08.04.2004)
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Journal Article
Antiarrhythmic efficacy of selective blockade of the cardiac slowly activating delayed rectifier current, IKs, in canine models of malignant ischemic ventricular arrhythmia
LYNCH, J. J, HOULE, M. S, CLAREMON, D. A, BILLMAN, G. E, STUMP, G. L, WALLACE, A. A, GILBERTO, D. B, JAHANSOUZ, H, SMITH, G. R, TEBBEN, A. J, LIVERTON, N. J, SELNICK, H. G
Published in Circulation (New York, N.Y.) (1999)
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Published in Circulation (New York, N.Y.) (1999)
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Orally Efficacious NR2B-Selective NMDA Receptor Antagonists
Claiborne, Christopher F, McCauley, John A, Libby, Brian E, Curtis, Neil R, Diggle, Helen J, Kulagowski, Janusz J, Michelson, Stuart R, Anderson, Kenneth D, Claremon, David A, Freidinger, Roger M, Bednar, Rodney A, Mosser, Scott D, Gaul, Stanley L, Connolly, Thomas M, Condra, Cindra L, Bednar, Bohumil, Stump, Gary L, Lynch, Joseph J, Macaulay, Alison, Wafford, Keith A, Koblan, Kenneth S, Liverton, Nigel J
Published in Bioorganic & medicinal chemistry letters (24.02.2003)
Published in Bioorganic & medicinal chemistry letters (24.02.2003)
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Journal Article
Class III Antiarrhythmic Activity in Vivo by Selective Blockade of the Slowly Activating Cardiac Delayed Rectifier Potassium Current I Ks by (R)-2-(2,4- Trifluoromethyl)-N-[2-oxo-5-phenyl- 1-(2,2,2-trifluoroethyl)-2,3-dihydro- 1H-benzo[e][1,4]diazepin-3-yl]acetamide
Selnick, Harold G, Liverton, Nigel J, Baldwin, John J, Butcher, John W, Claremon, David A, Elliott, Jason M, Freidinger, Roger M, King, Stella A, Libby, Brian E, McIntyre, Charles J, Pribush, David A, Remy, David C, Smith, Garry R, Tebben, Andrew J, Jurkiewicz, Nancy K, Lynch, Joseph J, Salata, Joseph J, Sanguinetti, Michael C, Siegl, Peter K. S, Slaughter, Donald E, Vyas, Kamlesh
Published in Journal of medicinal chemistry (21.11.1997)
Published in Journal of medicinal chemistry (21.11.1997)
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Kinetic characterization of novel NR2B antagonists using fluorescence detection of calcium flux
Bednar, Bohumil, Cunningham, Michael E, Kiss, Laszlo, Cheng, Gong, McCauley, John A, Liverton, Nigel J, Koblan, Kenneth S
Published in Journal of neuroscience methods (30.08.2004)
Published in Journal of neuroscience methods (30.08.2004)
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Journal Article
Pyridazine based inhibitors of p38 MAPK
McIntyre, Charles J, Ponticello, Gerald S, Liverton, Nigel J, O’Keefe, Stephen J, O’Neill, Edward A, Pang, Margaret, Schwartz, Cheryl D, Claremon, David A
Published in Bioorganic & medicinal chemistry letters (25.02.2002)
Published in Bioorganic & medicinal chemistry letters (25.02.2002)
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Journal Article
Antiarrhythmic Efficacy of Selective Blockade of the Cardiac Slowly Activating Delayed Rectifier Current, I Ks , in Canine Models of Malignant Ischemic Ventricular Arrhythmia
Lynch, Joseph J., Houle, Melanie S., Stump, Gary L., Wallace, Audrey A., Gilberto, David B., Jahansouz, Hossain, Smith, Garry R., Tebben, Andrew J., Liverton, Nigel J., Selnick, Harold G., Claremon, David A., Billman, George E.
Published in Circulation (New York, N.Y.) (02.11.1999)
Published in Circulation (New York, N.Y.) (02.11.1999)
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Total synthesis of the latrunulins
SMITH, A. B, LEAHY, J. W, NODA, I, REMISZEWSKI, S. W, LIVERTON, N. J, ZIBUCK, R
Published in Journal of the American Chemical Society (1992)
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Published in Journal of the American Chemical Society (1992)
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