Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer
Chiosis, Gabriela, Rodina, Anna, Vilenchik, Maria, Moulick, Kamalika, Aguirre, Julia, Kim, Joungnam, Chiang, Anne, Litz, Julie, Clement, Cristina C, Kang, Yanlong, She, Yuhong, Wu, Nian, Felts, Sara, Wipf, Peter, Massague, Joan, Jiang, Xuejun, Brodsky, Jeffrey L, Krystal, Geoffrey W
Published in Nature chemical biology (01.08.2007)
Published in Nature chemical biology (01.08.2007)
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The Insulin-Like Growth Factor-I Receptor Kinase Inhibitor, NVP-ADW742, Sensitizes Small Cell Lung Cancer Cell Lines to the Effects of Chemotherapy
WARSHAMANA-GREENE, G. Sakuntala, LITZ, Julie, BUCHDUNGER, Elisabeth, GARCIA-ECHEVERRIA, Carlos, HOFMANN, Francesco, KRYSTAL, Geoffrey W
Published in Clinical cancer research (15.02.2005)
Published in Clinical cancer research (15.02.2005)
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The Selective Tyrosine Kinase Inhibitor STI571 Inhibits Small Cell Lung Cancer Growth
KRYSTAL, G. W, HONSAWEK, S, LITZ, J, BUCHDUNGER, E
Published in Clinical cancer research (01.08.2000)
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Published in Clinical cancer research (01.08.2000)
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The insulin-like growth factor-I (IGF-I) receptor kinase inhibitor NVP-ADW742, in combination with STI571, delineates a spectrum of dependence of small cell lung cancer on IGF-I and stem cell factor signaling
Warshamana-Greene, G Sakuntala, Litz, Julie, Buchdunger, Elisabeth, Hofmann, Francesco, García-Echeverría, Carlos, Krystal, Geoffrey W
Published in Molecular cancer therapeutics (01.05.2004)
Published in Molecular cancer therapeutics (01.05.2004)
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Flavopiridol Potently Induces Small Cell Lung Cancer Apoptosis during S Phase in a Manner That Involves Early Mitochondrial Dysfunction
LITZ, Julie, CARLSON, Patricia, SAKUNTALA WARSHAMANA-GREENE, G, GRANT, Steven, KRYSTAL, Geoffrey W
Published in Clinical cancer research (01.10.2003)
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Published in Clinical cancer research (01.10.2003)
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Inhibition of phosphatidylinositol 3-kinase-Akt signaling blocks growth, promotes apoptosis, and enhances sensitivity of small cell lung cancer cells to chemotherapy
Krystal, Geoffrey W, Sulanke, Geoffrey, Litz, Julie
Published in Molecular cancer therapeutics (01.09.2002)
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Published in Molecular cancer therapeutics (01.09.2002)
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The multi-targeted kinase inhibitor SU5416 inhibits small cell lung cancer growth and angiogenesis, in part by blocking Kit-mediated VEGF expression
Litz, Julie, Sakuntala Warshamana-Greene, G., Sulanke, Geoffrey, Lipson, Kenneth E., Krystal, Geoffrey W.
Published in Lung cancer (Amsterdam, Netherlands) (01.12.2004)
Published in Lung cancer (Amsterdam, Netherlands) (01.12.2004)
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Inhibition of Phosphatidylinositol 3-Kinase-Akt Signaling Blocks Growth, Promotes Apoptosis, and Enhances Sensitivity of Small Cell Lung Cancer Cells to Chemotherapy 1 This work was supported in part by a Merit Review Award from the Department of Veterans Affairs and a grant from the Virginia Commonwealth Health Research Board. 1
Geoffrey W. Krystal, Geoffrey Sulanke, Julie Litz
Published in Molecular cancer therapeutics (01.09.2002)
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Published in Molecular cancer therapeutics (01.09.2002)
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Hormonal regulation of cholesterol 7 alpha-hydroxylase mRNA levels and transcriptional activity in primary rat hepatocyte cultures
HYLEMON, P. B, GURLEY, E. C, TODD STRAVITZ, R, LITZ, J. S, PANDAK, W. M, CHIANG, J. Y. L, RENO VLAHCEVIC, Z
Published in The Journal of biological chemistry (25.08.1992)
Published in The Journal of biological chemistry (25.08.1992)
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A 42-kD Tyrosine Kinase Substrate Linked to Chromaffin Cell Secretion Exhibits an Associated MAP Kinase Activity and Is Highly Related to a 42-kD Mitogen-Stimulated Protein in Fibroblasts
Ely, Constance M., Oddie, Karen M., Litz, Julie S., Rossomando, Anthony J., Kanner, Steven B., Sturgill, Thomas W., Parsons, Sarah J.
Published in The Journal of cell biology (01.03.1990)
Published in The Journal of cell biology (01.03.1990)
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