GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis
Kremer, Daniel M., Nelson, Barbara S., Lin, Lin, Yarosz, Emily L., Halbrook, Christopher J., Kerk, Samuel A., Sajjakulnukit, Peter, Myers, Amy, Thurston, Galloway, Hou, Sean W., Carpenter, Eileen S., Andren, Anthony C., Nwosu, Zeribe C., Cusmano, Nicholas, Wisner, Stephanie, Mbah, Nneka E., Shan, Mengrou, Das, Nupur K., Magnuson, Brian, Little, Andrew C., Savani, Milan R., Ramos, Johanna, Gao, Tina, Sastra, Stephen A., Palermo, Carmine F., Badgley, Michael A., Zhang, Li, Asara, John M., McBrayer, Samuel K., di Magliano, Marina Pasca, Crawford, Howard C., Shah, Yatrik M., Olive, Kenneth P., Lyssiotis, Costas A.
Published in Nature communications (11.08.2021)
Published in Nature communications (11.08.2021)
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Journal Article
Direct cysteine sulfenylation drives activation of the Src kinase
Heppner, David E., Dustin, Christopher M., Liao, Chenyi, Hristova, Milena, Veith, Carmen, Little, Andrew C., Ahlers, Bethany A., White, Sheryl L., Deng, Bin, Lam, Ying-Wai, Li, Jianing, van der Vliet, Albert
Published in Nature communications (30.10.2018)
Published in Nature communications (30.10.2018)
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Journal Article
IL-4/IL-13 Stimulated Macrophages Enhance Breast Cancer Invasion Via Rho-GTPase Regulation of Synergistic VEGF/CCL-18 Signaling
Little, Andrew C, Pathanjeli, Pragathi, Wu, Zhifen, Bao, Liwei, Goo, Laura E, Yates, Joel A, Oliver, C Ryan, Soellner, Matthew B, Merajver, Sofia D
Published in Frontiers in oncology (31.05.2019)
Published in Frontiers in oncology (31.05.2019)
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Journal Article
Breast cancers utilize hypoxic glycogen stores via PYGB, the brain isoform of glycogen phosphorylase, to promote metastatic phenotypes
Altemus, Megan A, Goo, Laura E, Little, Andrew C, Yates, Joel A, Cheriyan, Hannah G, Wu, Zhi Fen, Merajver, Sofia D
Published in PloS one (19.09.2019)
Published in PloS one (19.09.2019)
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Journal Article
Acrolein and thiol-reactive electrophiles suppress allergen-induced innate airway epithelial responses by inhibition of DUOX1 and EGFR
Danyal, Karamatullah, de Jong, Willem, O'Brien, Edmund, Bauer, Robert A, Heppner, David E, Little, Andrew C, Hristova, Milena, Habibovic, Aida, van der Vliet, Albert
Published in American journal of physiology. Lung cellular and molecular physiology (01.11.2016)
Published in American journal of physiology. Lung cellular and molecular physiology (01.11.2016)
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Journal Article
RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers
Abraham, Hannah G., Ulintz, Peter J., Goo, Laura, Yates, Joel A., Little, Andrew C., Bao, Liwei, Wu, Zhifen, Merajver, Sofia D.
Published in Frontiers in oncology (26.08.2021)
Published in Frontiers in oncology (26.08.2021)
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Journal Article
Internalized FGF-2-Loaded Nanoparticles Increase Nuclear ERK1/2 Content and Result in Lung Cancer Cell Death
Miao, Tianxin, Little, Andrew C, Aronshtam, Alexander, Marquis, Taylor, Fenn, Spencer L, Hristova, Milena, Krementsov, Dimitry N, Vliet, Albert van der, Spees, Jeffrey L, Oldinski, Rachael A
Published in Nanomaterials (Basel, Switzerland) (27.03.2020)
Published in Nanomaterials (Basel, Switzerland) (27.03.2020)
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Journal Article
Paradoxical roles of dual oxidases in cancer biology
Little, Andrew C., Sulovari, Arvis, Danyal, Karamatullah, Heppner, David E., Seward, David J., van der Vliet, Albert
Published in Free radical biology & medicine (01.09.2017)
Published in Free radical biology & medicine (01.09.2017)
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Journal Article
Dysregulated Redox Regulation Contributes to Nuclear EGFR Localization and Pathogenicity in Lung Cancer
Little, Andrew C., Hristova, Milena, van Lith, Loes, Schiffers, Caspar, Dustin, Christopher M., Habibovic, Aida, Danyal, Karamatullah, Heppner, David E., Lin, Miao-Chong J., van der Velden, Jos, Janssen-Heininger, Yvonne M., van der Vliet, Albert
Published in Scientific reports (19.03.2019)
Published in Scientific reports (19.03.2019)
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Journal Article
Abstract 1681: DUOX1 expression in lung cancer disrupts pro-oncogenic activation mechanisms and localization of Src and EGFR
Little, Andrew C., Danyal, Karamatullah, Bauer, Robert A., Heppner, David E., Hristova, Milena, Dustin, Christopher, Habibovic, Aida, van der Vliet, Albert
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Development of an Enhanced-Throughput Radial Cell Migration Device
Oliver, C. Ryan, Little, Andrew C., Westerhof, Trisha M., Pathanjeli, Pragathi, Yates, Joel A., Merajver, Sofia D.
Published in SLAS technology (01.04.2021)
Published in SLAS technology (01.04.2021)
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Journal Article
Abstract 2044: Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) modulates VEGF-C and VEGF-D secretion in the triple negative breast cancer cell line MDA-MB-231
Caceres, Sara, Little, Andrew C., Yates, Joel A., Gilani, Rabia A., Merajver, Sofia D.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 4518: IL-4/IL-13 stimulated tumor-associated macrophages enhance breast cancer cell invasion through Rho-GTPase signaling
Little, Andrew C., Pathanjeli, Pragathi, Wu, Zhifen, Bao, Liwei, Goo, Laura, Yates, Joel A., Merajver, Sofia D.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 4363: Effects of the small GTPase RhoC on inflammatory breast cancer metabolism
Goo, Laura E., Yates, Joel A., Little, Andrew C., Kremer, Daniel, Kovalenko, Ilya, Oliver, Christopher R., Westerhof, Trisha, Wu, Zhifen, Vandecan, Nathalie, Bao, Liwei, Ulintz, Peter J., Lyssiotis, Costas A., Merajver, Sofia D.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Development of a high-throughput radial migration device
C Ryan Oliver, Little, Andrew C, Westerhof, Trisha M, Pathanjeli, Pragathi, Yates, Joel A, Merajver, Sofia D
Published in bioRxiv (28.02.2020)
Published in bioRxiv (28.02.2020)
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Paper
Integration of high-content fluorescence imaging into the metabolic flux assay reveals insights into mitochondrial properties and functions
Little, Andrew C, Kovalenko, Ilya, Goo, Laura E, Hong, Hanna S, Kerk, Samuel A, Yates, Joel A, Purohit, Vinee, Lombard, David B, Merajver, Sofia D, Lyssiotis, Costas A
Published in bioRxiv (04.09.2019)
Published in bioRxiv (04.09.2019)
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Paper